...CRISPR loci confer adaptive, sequence-based immunity against viruses and plasmids. CRISPR interference is specified by C...
We used ChIP-seq to map binding of the CRISPR surveillance complex, Cascade, in a Salmonella enterica serovar Typhimuriu...
The aim of the experiment is to assess the robustness of CRISPR-Cas9 based genetic engineering. Using RNA sequencing, we...
...CRISPR arrays or cells with the CRISPR-I array deleted to determine if off-target events driven by endogenous spacers af...
...CRISPR arrays or cells with the CRISPR-I array deleted to determine if off-target events driven by endogenous spacers af...
...CRISPR-Cas effector complexes are comprised of CRISPR RNAs (crRNAs) that contain sequences homologous to the invading nu...
...CRISPR editing genomic locus containing SNORD50A/B We have used CRISPR genome editing tool to KD snoRNAs SNORD50A/B from...
Identifying putative transcription factor target genes by combining CRISPR/Cas9-based transcriptional activation with RN...
...CRISPR protospacer targeted by spacer 8 of the E. coli CRISPR-I array. We transformed the plasmids as a pool into delta ...
By a robust unbiased ChIP-seq approach, we demonstrated that CRISPR/Cas9 had crRNA-specific off-target binding activitie...
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