Home LiteratureArticle Details
PMID: 9746315 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Cytoskeleton and mitochondrial morphology and function.

Molecular and cellular biochemistry ·Vol. 184 ·No. 1-2 ·1998-07-00 ·Pages 101-5

Rappaport L, Oliviero P, Samuel JL

Abstract

It has been well established that the cytoskeleton is an essential modulator of cell morphology and motility, intracytoplasmic transport and mitosis, however cytoskeletal linkage to the organelles has not been unequivocally demonstrated. Indeed, cytoskeleton appears to be essential in determining and modulating gene phenotype as a function of cellular environment. According to recent studies, the organization of the cytoskeleton network together with associated protein(s) could be essential in regulating mitochondrial function and particularly the permeability of the mitochondrial outer membrane to ADP. The aim of this chapter is to summarize the main properties of the cytoskeletal environment of mitochondria and the possible role(s) of this network in mitochondrial function in myocytes.

MeSH Terms
Adenosine Diphosphate/metabolism Animals Cell Membrane Permeability/physiology Cytoskeleton/physiology Membrane Proteins/physiology Microscopy, Electron Microtubule-Associated Proteins/physiology Mitochondria/physiology Muscles/ultrastructure Rats
Chemicals
Membrane Proteins Microtubule-Associated Proteins Adenosine Diphosphate
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Rappaport L
Unité 127 INSERM, IFR Circulation, University D Diderot, Hôpital Lariboisière, Paris, France.
Oliviero P
Samuel J L
References (43)
43 references, click to expand
  1. On the regulation of cellular energetics in health and disease.
    Mol Cell Biochem. 1996 Jul-Aug;160-161:195-208 PMID: 8901474
  2. Metabolic compartmentation and substrate channelling in muscle cells. Role of coupled creatine kinases in in vivo regulation of cellular respiration--a synthesis.
    Mol Cell Biochem. 1994 Apr-May;133-134:155-92 PMID: 7808453
  3. Behavior of mitochondria in the living cell.
    Int Rev Cytol. 1990;122:1-63 PMID: 2246114
  4. Morphological evidence for the participation of microtubules in axonal transport.
    Ann N Y Acad Sci. 1975 Jun 30;253:472-506 PMID: 50033
  5. Fodrin: axonally transported polypeptides associated with the internal periphery of many cells.
    J Cell Biol. 1981 Sep;90(3):631-42 PMID: 6169732
  6. MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria.
    J Cell Biol. 1994 Sep;126(6):1375-91 PMID: 8089172
  7. Binding of lipid droplets and mitochondria to intermediate filaments in rat Leydig cells.
    J Reprod Fertil. 1993 May;98(1):209-17 PMID: 8345465
  8. Actin structure and function: roles in mitochondrial organization and morphogenesis in budding yeast and identification of the phalloidin-binding site.
    Mol Biol Cell. 1993 Dec;4(12):1277-94 PMID: 8167410
  9. Disruption of muscle architecture and myocardial degeneration in mice lacking desmin.
    J Cell Biol. 1996 Sep;134(5):1255-70 PMID: 8794866
  10. Imaging cytoskeleton--mitochondrial membrane attachments by embedment-free electron microscopy of saponin-extracted cells.
    Proc Natl Acad Sci U S A. 1990 Nov;87(21):8565-9 PMID: 2236067
  11. Rethinking cell structure.
    Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5251-7 PMID: 7777493
  12. Immunological quantitation and localization of tubulin in adult rat heart isolated myocytes.
    Eur J Cell Biol. 1983 Jul;31(1):99-106 PMID: 6137364
  13. Mitochondrial motility in axons: membranous organelles may interact with the force generating system through multiple surface binding sites.
    Cell Motil. 1984;4(2):89-101 PMID: 6733777
  14. Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton.
    J Cell Sci. 1993 Mar;104 ( Pt 3):613-27 PMID: 8314865
  15. Purification of a protein having pore forming activity from the rat liver mitochondrial outer membrane.
    Biochem J. 1982 Oct 15;208(1):77-82 PMID: 6297464
  16. Putative association of mitochondria with a subpopulation of intermediate-sized filaments in cultured human skin fibroblasts.
    Cell. 1982 Dec;31(3 Pt 2):681-92 PMID: 6186387
  17. Study of regulation of mitochondrial respiration in vivo. An analysis of influence of ADP diffusion and possible role of cytoskeleton.
    Biochim Biophys Acta. 1997 Nov 10;1322(1):41-59 PMID: 9398078
  18. Studies on the interaction between mitochondria and the cytoskeleton.
    J Bioenerg Biomembr. 1989 Aug;21(4):507-18 PMID: 2478536
  19. Are cytoskeletal components involved in the control of hepatic carnitine palmitoyltransferase I activity?
    Biochem Biophys Res Commun. 1996 Jul 25;224(3):754-9 PMID: 8713118
  20. Organelle-cytoskeletal interactions: actin mutations inhibit meiosis-dependent mitochondrial rearrangement in the budding yeast Saccharomyces cerevisiae.
    Mol Biol Cell. 1995 Oct;6(10):1381-96 PMID: 8573793
  21. Association of annexin V with mitochondria.
    FEBS Lett. 1993 Aug 23;329(1-2):79-83 PMID: 8354413
  22. Contact sites between mitochondrial envelope membranes. Structure and function in energy- and protein-transfer.
    Biochim Biophys Acta. 1991 Nov 13;1071(3):291-312 PMID: 1958691
  23. Mitochondria are associated with microtubules and not with intermediate filaments in cultured fibroblasts.
    Proc Natl Acad Sci U S A. 1982 Jan;79(1):123-6 PMID: 6275382
  24. Subcellular localization of the F5 protein to the neuronal membrane-associated cytoskeleton.
    J Neurosci Res. 1994 Jun 15;38(3):348-57 PMID: 7932868
  25. Association of mitochondria with microtubules in cultured cells.
    Proc Natl Acad Sci U S A. 1978 Aug;75(8):3863-6 PMID: 80800
  26. Cross-linker system between neurofilaments, microtubules, and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method.
    J Cell Biol. 1982 Jul;94(1):129-42 PMID: 6181077
  27. Statistical analysis of the surface distribution of microtubule-associated proteins (MAPs) bound in vitro to rat brain mitochondria and labelled by 10 nm gold-coupled antibodies.
    Bull Assoc Anat (Nancy). 1994 Mar;78(240):47-51 PMID: 8054696
  28. Regulation of mitochondrial morphology and inheritance by Mdm10p, a protein of the mitochondrial outer membrane.
    J Cell Biol. 1994 Sep;126(6):1361-73 PMID: 8089171
  29. Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons.
    J Cell Biol. 1995 Dec;131(5):1315-26 PMID: 8522592
  30. Identification of a novel mammalian annexin. cDNA cloning, sequence analysis, and ubiquitous expression of the annexin XI gene.
    J Biol Chem. 1992 Mar 15;267(8):5416-23 PMID: 1372001
  31. Nuclear and mitochondrial inheritance in yeast depends on novel cytoplasmic structures defined by the MDM1 protein.
    J Cell Biol. 1992 Jul;118(2):385-95 PMID: 1378448
  32. From laminin to lamin: regulation of tissue-specific gene expression by the ECM.
    Trends Cell Biol. 1995 Jan;5(1):1-4 PMID: 14731421
  33. Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension.
    Biophys J. 1994 Jun;66(6):2181-9 PMID: 8075352
  34. Microtubules in cardiac myocytes.
    Int Rev Cytol. 1988;113:101-43 PMID: 2976409
  35. Control of cellular respiration in vivo by mitochondrial outer membrane and by creatine kinase. A new speculative hypothesis: possible involvement of mitochondrial-cytoskeleton interactions.
    J Mol Cell Cardiol. 1995 Jan;27(1):625-45 PMID: 7760382
  36. Interactions between brain mitochondria and cytoskeleton: evidence for specialized outer membrane domains involved in the association of cytoskeleton-associated proteins to mitochondria in situ and in vitro.
    Microsc Res Tech. 1994 Feb 15;27(3):233-61 PMID: 8204913
  37. The Ninth Sir Hans Krebs Lecture. Compartmentation and communication in living systems. Ligand conduction: a general catalytic principle in chemical, osmotic and chemiosmotic reaction systems.
    Eur J Biochem. 1979 Mar 15;95(1):1-20 PMID: 378655
  38. Microtubules mediate mitochondrial distribution in fission yeast.
    Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11664-8 PMID: 8876193
  39. KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria.
    Cell. 1994 Dec 30;79(7):1209-20 PMID: 7528108
  40. Microtubules and desmin filaments during onset of heart hypertrophy in rat: a double immunoelectron microscope study.
    Circ Res. 1987 Mar;60(3):327-36 PMID: 2953507
  41. Cardiovascular lesions and skeletal myopathy in mice lacking desmin.
    Dev Biol. 1996 May 1;175(2):362-6 PMID: 8626040
  42. Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria.
    Microsc Res Tech. 1994 Feb 15;27(3):198-219 PMID: 8204911
  43. A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression.
    Curr Opin Cell Biol. 1995 Oct;7(5):736-47 PMID: 8573350
Article Info
Journal
Molecular and cellular biochemistry
Abbr.
Mol Cell Biochem
ISSN
0300-8177
Published
1998-07-00
Pages
101-5
Language
English
Region
Netherlands
NLM ID
0364456
Subset
IM
External Links
PubMed source View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2