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PMID: 9025229 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Murine coronavirus infection: a paradigm for virus-induced demyelinating disease.

Trends in microbiology ·Vol. 5 ·No. 1 ·1997-01-00 ·Pages 9-14

Lane TE, Buchmeier MJ

Abstract

A variety of neurological diseases in humans, including multiple sclerosis (MS), have been postulated to have a viral etiology. The use of animal models provides insights into potential mechanism(s) involved in the disease process. The murine coronavirus-induced demyelinating disease in rodents is one such model for demyelinating disease in humans.

MeSH Terms
Animals Chronic Disease Coronavirus Infections/etiology,immunology Demyelinating Diseases/epidemiology,etiology,immunology Disease Models, Animal Humans Mice Molecular Biology/methods Multiple Sclerosis/epidemiology,virology Murine hepatitis virus/immunology,pathogenicity,physiology Rats Virus Diseases/diagnosis,genetics Virus Latency
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Lane T E
Dept of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA.
Buchmeier M J
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Article Info
Journal
Trends in microbiology
Abbr.
Trends Microbiol
ISSN
0966-842X
DOI
10.1016/S0966-842X(97)81768-4
Published
1997-01-00
Pages
9-14
Language
English
Region
England
NLM ID
9310916
PMCID
PMC7133370
Subset
IM
Grants
NIAID NIH HHS · AI25913 · United States
Corrections
CommentIn
PMID: 9141187
External Links
PubMed source DOI: 10.1016/S0966-842X(97)81768-4 PMC Full Text View journal details
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