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PMID: 853566 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Multiple copies of human adenovirus 12 genomes are integrated in virus-induced hamster tumors.

Journal of virology ·Vol. 22 ·No. 1 ·1977-04-00 ·Pages 238-42

Green MR, Mackey JK, Green M

Abstract

Tumors induced in hamsters by highly oncogenic human adenovirus 12 contain multiple copies of 90 to 100% of the viral genome in an integrated form.

MeSH Terms

Adenoviruses, Human/metabolism Animals Cell Transformation, Neoplastic Cricetinae DNA, Neoplasm/metabolism DNA, Viral/metabolism Neoplasm Transplantation Neoplasms, Experimental/metabolism Nucleic Acid Hybridization

Chemicals

DNA, Neoplasm DNA, Viral

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Green M R

Mackey J K

Green M

References (16)

16 references, click to expand

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Oncogenic viruses.
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A unique pattern of integrated viral genes in hamster cells transformed by highly oncogenic human adenovirus 12.
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Analysis of multiple viral genome fragments in adenovirus 7-transformed hamster cells.
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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.22.1.238-242.1977

Published

1977-04-00

Pages

238-42

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC515707

Subset

External Links

PubMed source DOI: 10.1128/JVI.22.1.238-242.1977 PMC Full Text View journal details

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Multiple copies of human adenovirus 12 genomes are integrated in virus-induced hamster tumors.

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