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PMID: 1057486 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Analysis of multiple viral genome fragments in adenovirus 7-transformed hamster cells.

Cold Spring Harbor symposia on quantitative biology ·Vol. 39 Pt 1 ·1975-00-00 ·Pages 633-6

Fujinaga K, Sekikawa K, Yamazaki H, Green M

Abstract

The presence of multiple copies of a portion of the viral genome was demonstrated in Ad7-transformed cells by a new method based on the kinetic analysis of labeled viral DNA reassociation in the presence of unlabeled transformed cell DNA. DNA-DNA homology measurement utilizing defined DNA fragments (restriction endonuclease digests) as labeled probes supported the above conclusion.

MeSH Terms

Adenoviridae/analysis Cell Line Cell Transformation, Neoplastic Chromosomes/analysis DNA Restriction Enzymes DNA, Viral/analysis Kinetics Models, Biological Molecular Weight Nucleic Acid Hybridization

Chemicals

DNA, Viral DNA Restriction Enzymes

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Fujinaga K

Sekikawa K

Yamazaki H

Green M

Article Info

Journal

Cold Spring Harbor symposia on quantitative biology

Abbr.

Cold Spring Harb Symp Quant Biol

ISSN

0091-7451

DOI

10.1101/sqb.1974.039.01.076

Published

1975-00-00

Pages

633-6

Language

English

Region

United States

NLM ID

1256107

Subset

External Links

PubMed source DOI: 10.1101/sqb.1974.039.01.076

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Analysis of multiple viral genome fragments in adenovirus 7-transformed hamster cells.

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