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PMID: 6721845 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Is N-acetylglutamate a short-term regulator of urea synthesis?

The Biochemical journal ·Vol. 218 ·No. 3 ·1984-03-15 ·Pages 991-4

Lund P, Wiggins D

Abstract

A method is described for determining N-acetylglutamate as glutamate. N-Acetylglutamate content of hepatocytes from 48 h-starved rats is high. It shows no parallelism with rates of urea synthesis from glutamine. We question its accepted function as a short-term regulator of urea synthesis.

MeSH Terms
Animals Female Glutamates/analysis,metabolism Glutamine/metabolism In Vitro Techniques Liver/analysis,cytology,metabolism Methods Rats Rats, Inbred Strains Urea/biosynthesis
Chemicals
Glutamates Glutamine Urea N-acetylglutamic acid
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Lund P
Wiggins D
References (20)
20 references, click to expand
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Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj2180991
Published
1984-03-15
Pages
991-4
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1153434
Subset
IM
External Links
PubMed source DOI: 10.1042/bj2180991 PMC Full Text View journal details
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