A size analysis of the adenovirus replicon.
The linear double-stranded genome of adenovirus DNA replicates semiconservatively from two origins of replication at either of the two molecular ends. Using an in vitro replication system which is able to initiate de novo DNA synthesis we have mapped the origin of DNA replication within the terminal 19 bp of the viral genome. Our conclusions are based on the use of different natural DNA templates, i.e., adenovirus type 2 and mouse adenovirus Fl DNA. In addition, we have employed linearized plasmid DNA templates which contain cloned terminal restriction enzyme fragments as well as chemically synthesized adenovirus termini of different length.
21 references, click to expand
-
Calcium-dependent bacteriophage DNA infection.J Mol Biol. 1970 Oct 14;53(1):159-62 PMID: 4922220
-
The infectivity of adenovirus 5 DNA-protein complex.Virology. 1976 Dec;75(2):442-56 PMID: 1032904
-
Adenovirus DNA: structure and function of a novel replicon.Cell. 1978 Aug;14(4):761-73 PMID: 357012
-
Adenovirus DNA replication in vitro.Proc Natl Acad Sci U S A. 1979 Feb;76(2):655-9 PMID: 284391
-
Sequencing end-labeled DNA with base-specific chemical cleavages.Methods Enzymol. 1980;65(1):499-560 PMID: 6246368
-
Construction and characterization of new cloning vehicles. IV. Deletion derivatives of pBR322 and pBR325.Gene. 1980 May;9(3-4):287-305 PMID: 6248430
-
Initiation of adenovirus DNA replication.J Virol. 1980 Sep;35(3):662-71 PMID: 7420538
-
Replication of mouse adenovirus strain FL DNA.Virology. 1981 Feb;109(1):1-12 PMID: 6927844
-
Adenovirus DNA replication in vitro: a protein linked to the 5' end of nascent DNA strands.J Virol. 1981 Jan;37(1):139-47 PMID: 7218423
-
Nucleotide sequences at the termini of phi 29 DNA.Proc Natl Acad Sci U S A. 1981 Mar;78(3):1336-40 PMID: 6262789
-
Adenovirus DNA replication in vitro: purification of the terminal protein in a functional form.Proc Natl Acad Sci U S A. 1981 Nov;78(11):6779-83 PMID: 6947251
-
Function of adenovirus terminal protein in the initiation of DNA replication.Proc Natl Acad Sci U S A. 1982 Apr;79(7):2221-5 PMID: 6954537
-
A common sequence in the inverted terminal repetitions of human and avian adenoviruses.Gene. 1982 May;18(2):193-7 PMID: 6290323
-
Adenovirus terminal protein precursor. Partial amino acid sequence and the site of covalent linkage to virus DNA.J Biol Chem. 1982 Nov 25;257(22):13499-506 PMID: 7142163
-
Conserved sequences at the origin of adenovirus DNA replication.J Virol. 1982 Nov;44(2):530-7 PMID: 7143575
-
The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers.Gene. 1982 Oct;19(3):259-68 PMID: 6295879
-
Replication of origin containing adenovirus DNA fragments that do not carry the terminal protein.Nucleic Acids Res. 1983 Apr 11;11(7):1975-89 PMID: 6300787
-
Improvements in the phosphoramidite procedure for the synthesis of oligodeoxyribonucleotides.Nucleic Acids Res. 1983 May 11;11(9):2575-84 PMID: 6856470
-
In vitro replication directed by a cloned adenovirus origin.Gene. 1983 Sep;23(3):293-305 PMID: 6628993
-
Mutational mapping of a cloned adenovirus origin.Gene. 1983 Sep;23(3):307-13 PMID: 6628994
-
Defective expression of mouse adenovirus Fl in human cells.EMBO J. 1982;1(4):453-9 PMID: 6329682
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: product@genelibs.com
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
