A human T-cell antigen receptor beta chain gene maps to chromosome 7.

The EMBO journal ·Vol. 3 ·No. 10 ·1984-10-00 ·Pages 2347-9

Collins MK, Goodfellow PN, Dunne MJ, Spurr NK, Solomon E, Owen MJ

Abstract

cDNA clones which encode the human and mouse T cell antigen receptor beta chain gene have previously been isolated. We have used a mouse cDNA clone to map the chromosomal position of a human beta chain gene. Southern blot analysis of DNA prepared from somatic cell hybrids has assigned this gene to chromosome 7. The use of a hybrid containing a chromosome 7 translocation has further localised this gene to the region 7q22-qter.

MeSH Terms

Animals Chromosomes, Human, 6-12 and X DNA/analysis Humans Hybrid Cells/analysis Mice Nucleic Acid Hybridization Receptors, Antigen, T-Cell/genetics Translocation, Genetic

Chemicals

Receptors, Antigen, T-Cell DNA

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Collins M K

Goodfellow P N

Dunne M J

Spurr N K

Solomon E

Owen M J

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Article Info

Journal

The EMBO journal

Abbr.

EMBO J

ISSN

0261-4189

Published

1984-10-00

Pages

2347-9

Language

English

Region

England

NLM ID

8208664

PMCID

PMC557691

Subset

External Links

PubMed source PMC Full Text View journal details

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A human T-cell antigen receptor beta chain gene maps to chromosome 7.

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