Graphic methods to determine the function of nucleic acid sequences.

Nucleic acids research ·Vol. 12 ·No. 1 Pt 2 ·1984-01-11 ·Pages 521-38

Staden R

Abstract

We describe an interactive computer program (ANALYSEQ) that is used from a simple graphics terminal. The main purpose of the program is to determine the function of nucleic acid sequences but it also offers the simpler listing, searching and counting options. It contains methods to locate genes by looking for the effects that coding for a protein has on the coding sequence, to locate tRNA genes by looking for secondary structure and conserved bases, and methods to locate signals such as promoters. Techniques to identify unusual regions of sequence and to search for potential Z DNA-forming regions are also included. Most of the routines produce graphical output which gives ease of interpretation and allows superposition of several independent forms of analysis.

MeSH Terms

Animals Base Sequence Cloning, Molecular Codon Computers DNA/genetics Escherichia coli/genetics Genes Mice Minicomputers Operon RNA, Transfer/genetics Repetitive Sequences, Nucleic Acid Ribosomes/metabolism Software

Chemicals

Codon DNA RNA, Transfer

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Staden R

References (16)

16 references, click to expand

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Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/12.1part2.521

Published

1984-01-11

Pages

521-38

Language

English

Region

England

NLM ID

0411011

PMCID

PMC321068

Subset

External Links

PubMed source DOI: 10.1093/nar/12.1part2.521 PMC Full Text View journal details

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Graphic methods to determine the function of nucleic acid sequences.

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