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PMID: 6355116 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Nuclear RNA-protein interactions and messenger RNA processing.

The Journal of cell biology ·Vol. 97 ·No. 5 Pt 1 ·1983-11-00 ·Pages 1321-6

Pederson T

Abstract

Eucaryotic messenger RNA precursors are processed in nuclear ribonucleoprotein particles (hnRNP). Here recent work on the structure of hnRNP is reviewed, with emphasis on function. Detailed analysis of a specific case, the altered assembly of hnRNP in heat-shocked Drosophila and mammalian cells, leads to a general hypothesis linking hnRNP structure and messenger RNA processing.

MeSH Terms
Animals Base Sequence Heterogeneous-Nuclear Ribonucleoproteins Hot Temperature Models, Genetic Molecular Weight Nucleic Acid Conformation RNA, Messenger/metabolism Ribonucleoproteins/metabolism Transcription, Genetic
Chemicals
Heterogeneous-Nuclear Ribonucleoproteins RNA, Messenger Ribonucleoproteins
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Pederson T
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Article Info
Journal
The Journal of cell biology
Abbr.
J Cell Biol
ISSN
0021-9525
DOI
10.1083/jcb.97.5.1321
Published
1983-11-00
Pages
1321-6
Language
English
Region
United States
NLM ID
0375356
PMCID
PMC2112690
Subset
IM
Grants
NCI NIH HHS · CA-13400 · United States
NIGMS NIH HHS · GM-21595 · United States
NIGMS NIH HHS · GM-28274 · United States
External Links
PubMed source DOI: 10.1083/jcb.97.5.1321 PMC Full Text View journal details
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