Home LiteratureArticle Details
PMID: 6254079 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Four heat shock proteins of Drosophila melanogaster coded within a 12-kilobase region in chromosome subdivision 67B.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 77 ·No. 9 ·1980-09-00 ·Pages 5390-3

Corces V, Holmgren R, Freund R, Morimoto R, Meselson M

Abstract

Unique coding sequences for four heat shock proteins of Drosophila melanogaster, hsp 28, hsp 26, hsp 23, and hsp 22, are clustered in a 12-kilobase interval at chromosome subdivision 67B. The four genes are not transcribed in the same direction and each gives rise to a separate messenger RNA, with no indication of intervening sequences. Including the present results, the genes for all seven major heat shock proteins of D. melanogaster are now cloned are found to exhibit a variety of patterns of organization at the five loci they occupy.

MeSH Terms
Animals Bacteriophage lambda/genetics Base Sequence Chromosome Mapping Cloning, Molecular DNA Restriction Enzymes Drosophila melanogaster/genetics Escherichia coli/genetics Genetic Vectors Hot Temperature Nucleic Acid Hybridization Plasmids Protein Biosynthesis Proteins/genetics RNA, Messenger/metabolism
Chemicals
Proteins RNA, Messenger DNA Restriction Enzymes
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Corces V
Holmgren R
Freund R
Morimoto R
Meselson M
References (19)
19 references, click to expand
  1. The ribonuclease activity of crystallized pancreatic deoxyribonuclease.
    Anal Biochem. 1966 Feb;14(2):269-77 PMID: 5939865
  2. Nucleotide sequence analysis of deoxyribonucleic acid. VII. Characterization of Escherichia coli exonuclease 3 activity for possible use in terminal nucleotide sequence analysis of duplex deoxyribonucleic acid.
    J Biol Chem. 1972 Jul 25;247(14):4661-8 PMID: 4557850
  3. High resolution two-dimensional electrophoresis of proteins.
    J Biol Chem. 1975 May 25;250(10):4007-21 PMID: 236308
  4. Enzymatic in vitro synthesis of globin genes.
    Cell. 1976 Feb;7(2):279-88 PMID: 60178
  5. Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation.
    Proc Natl Acad Sci U S A. 1977 Oct;74(10):4370-4 PMID: 270678
  6. Translation in vitro of Drosophila heat-shock messages.
    J Mol Biol. 1977 Nov 25;117(1):279-83 PMID: 413926
  7. Spliced early mRNAs of simian virus 40.
    Proc Natl Acad Sci U S A. 1978 Mar;75(3):1274-8 PMID: 206891
  8. The effect of heat shock on gene expression in Drosophila melanogaster.
    Cold Spring Harb Symp Quant Biol. 1978;42 Pt 2:819-27 PMID: 98271
  9. pBR322 restriction map derived from the DNA sequence: accurate DNA size markers up to 4361 nucleotide pairs long.
    Nucleic Acids Res. 1978 Aug;5(8):2721-8 PMID: 358147
  10. The isolation of structural genes from libraries of eucaryotic DNA.
    Cell. 1978 Oct;15(2):687-701 PMID: 719759
  11. Sequence organization and transcription at two heat shock loci in Drosophila.
    Proc Natl Acad Sci U S A. 1978 Nov;75(11):5613-7 PMID: 103099
  12. The induction of gene activity in drosophilia by heat shock.
    Cell. 1979 Jun;17(2):241-54 PMID: 110462
  13. Improved methods for the formation and stabilization of R-loops.
    Nucleic Acids Res. 1979 Jun 11;6(7):2499-317 PMID: 379821
  14. Purification and mapping of specific mRNAs by hybridization-selection and cell-free translation.
    Proc Natl Acad Sci U S A. 1979 Oct;76(10):4927-31 PMID: 291909
  15. Genetic and molecular analysis of the 87A7 and 87C1 heat-inducible loci of D. melanogaster.
    Cell. 1979 Dec;18(4):1351-8 PMID: 117906
  16. Studies of cloned sequences from four Drosophila heat shock loci.
    Cell. 1979 Dec;18(4):1359-70 PMID: 117907
  17. Genetic mapping of the coding regions for three heat-shock proteins in Drosophila melanogaster.
    Genetics. 1979 Jul;92(3):891-902 PMID: 119669
  18. Sequencing end-labeled DNA with base-specific chemical cleavages.
    Methods Enzymol. 1980;65(1):499-560 PMID: 6246368
  19. Genes for three Drosophila heat-shock-induced proteins at a single locus.
    Proc Natl Acad Sci U S A. 1980 Apr;77(4):2134-7 PMID: 6769119
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.77.9.5390
Published
1980-09-00
Pages
5390-3
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC350064
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.77.9.5390 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2