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PMID: 6349822 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Immunocytochemical detection of calcium-binding protein in the cochlear and vestibular hair cells of the rat.

Cell and tissue research ·Vol. 232 ·No. 3 ·1983-00-00 ·Pages 691-6

Rabié A, Thomasset M, Legrand C

Abstract

Specific antibodies raised against human cerebellar calcium-binding protein (CaBP) intensely labelled the cochlear hair cells of the rat. The vestibular hair cells also stained weakly. In both inner and outer cochlear hair cells, the cuticular plate was the most stained area. These results suggest that CaBP may prevent excessive concentrations of intracellular calcium and thus modulate some Ca2+-mediated biochemical processes, especially at the level of the cuticular plate and stereocilia; CaBP could be involved in the mechanochemical coupling of hearing or vestibular function.

MeSH Terms
Animals Calcium-Binding Proteins/analysis Hair Cells, Auditory/analysis Hair Cells, Auditory, Inner/analysis Immunoenzyme Techniques Rats Rats, Inbred Strains S100 Calcium Binding Protein G/analysis Vestibule, Labyrinth/cytology
Chemicals
Calcium-Binding Proteins S100 Calcium Binding Protein G
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Rabié A
Thomasset M
Legrand C
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21 references, click to expand
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Article Info
Journal
Cell and tissue research
Abbr.
Cell Tissue Res
ISSN
0302-766X
DOI
10.1007/BF00216440
Published
1983-00-00
Pages
691-6
Language
English
Region
Germany
NLM ID
0417625
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00216440 View journal details
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