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The reticulocyte plasma membrane pathway of iron uptake as determined by the mechanism of alpha, alpha'-dipyridyl inhibition.
J Biol Chem. 1983 Jan 25;258(2):1146-51
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Protection against free radical formation by protein bound iron.
Toxicol Lett. 1982 Nov;14(1-2):27-34
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Production of superoxide and activity of superoxide dismutase in rabbit epididymal spermatozoa.
Biol Reprod. 1982 Dec;27(5):1109-18
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The generation of hydroxyl radicals following superoxide production by neutrophil NADPH oxidase.
FEBS Lett. 1982 Dec 27;150(2):300-2
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The role of superoxide and hydroxyl radicals in phospholipid peroxidation catalysed by iron salts.
FEBS Lett. 1982 Dec 27;150(2):454-8
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Ascorbate uptake by isolated rat alveolar macrophages and type II cells.
J Appl Physiol Respir Environ Exerc Physiol. 1983 Jan;54(1):208-14
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Hepatic lipid peroxidation in vivo in rats with chronic iron overload.
J Clin Invest. 1983 Mar;71(3):429-39
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Effect of a specific iron chelating agent on animal models of inflammation.
Ann Rheum Dis. 1983 Feb;42(1):89-93
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The effect of iron deficiency on experimental oral carcinogenesis in the rat.
Br J Cancer. 1983 Mar;47(3):413-8
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Transferrin binding and iron uptake in mouse hepatocytes.
Biochim Biophys Acta. 1983 Feb 16;762(1):102-10
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Spontaneous chemiluminescence of human breath. Spectrum, lifetime, temporal distribution, and correlation with peroxide.
J Biol Chem. 1983 Mar 25;258(6):3628-31
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A study of the reactivity of HO2/O2- with unsaturated fatty acids.
J Biol Chem. 1983 Apr 25;258(8):4759-61
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Protection against superoxide and hydrogen peroxide in synovial fluid from rheumatoid patients.
Clin Sci (Lond). 1981 Oct;61(4):483-6
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Production of formaldehyde during metabolism of dimethyl sulfoxide by hydroxyl radical generating systems.
Biochemistry. 1981 Oct 13;20(21):6006-12
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Unusual copper-induced sensitization of the biological damage due to superoxide radicals.
J Biol Chem. 1981 Dec 25;256(24):12632-5
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Oxygen, oxidases, and the essential trace metals.
Philos Trans R Soc Lond B Biol Sci. 1981 Aug 14;294(1071):119-28
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Hydroxyl radical production in body fluids. Roles of metal ions, ascorbate and superoxide.
Biochem J. 1981 Jul 15;198(1):125-31
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Iron and rheumatoid disease.
Lancet. 1982 Mar 13;1(8272):623
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Superoxide-dependent formation of hydroxyl radicals: detection of hydroxyl radicals by the hydroxylation of aromatic compounds.
Anal Biochem. 1981 Dec;118(2):328-35
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Inhibition of lipid peroxidation by the iron-binding protein lactoferrin.
Biochem J. 1981 Oct 1;199(1):259-61
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Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts. Detection of 'free' iron in biological systems by using bleomycin-dependent degradation of DNA.
Biochem J. 1981 Oct 1;199(1):263-5
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Survival and desferrioxamine in thalassaemia major.
Br Med J (Clin Res Ed). 1982 Apr 10;284(6322):1081-4
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Copper- and zinc-containing superoxide dismutase, manganese-containing superoxide dismutase, catalase, and glutathione peroxidase in normal and neoplastic human cell lines and normal human tissues.
Cancer Res. 1982 May;42(5):1955-61
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Effects of antioxidant nutrient deficiency on the retina and retinal pigment epithelium of albino rats: a light and electron microscopic study.
Exp Eye Res. 1982 Mar;34(3):339-69
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Stimulation of microsomal lipid peroxidation by iron and cysteine. Characterization and the role of free radicals.
Biochem J. 1983 Jun 15;212(3):549-54
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Copper salt-dependent hydroxyl radical formation. Damage to proteins acting as antioxidants.
Biochim Biophys Acta. 1983 Aug 23;759(1-2):38-41
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Evidence for role of hydroxyl radical in complement and neutrophil-dependent tissue injury.
J Clin Invest. 1983 Sep;72(3):789-801
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Direct demonstration that ferrous ion complexes of di- and triphosphate nucleotides catalyze hydroxyl free radical formation from hydrogen peroxide.
Arch Biochem Biophys. 1983 Aug;225(1):263-70
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Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals in the presence of copper salts: a physiologically significant reaction?
Arch Biochem Biophys. 1983 Aug;225(1):279-84
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Carotenoid pigments: their possible role in protecting against photooxidation in eyes and photoreceptor cells.
Proc R Soc Lond B Biol Sci. 1982 Aug 23;216(1202):71-85
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The incorporation of iron into apoferritin as mediated by ceruloplasmin.
Biochem Biophys Res Commun. 1983 Oct 14;116(1):244-50
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Non-protein-bound iron within bacterial cells and the action of bleomycin.
Biochem Int. 1984 Jan;8(1):89-94
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The anaemia of rheumatoid arthritis: the significance of iron deposits in the synovial membrane.
Australas Ann Med. 1970 May;19(2):97-104
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A mechanism for the production of ethylene from methional. The generation of the hydroxyl radical by xanthine oxidase.
J Biol Chem. 1970 Sep 25;245(18):4641-6
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Reactions of the oxyform of horseradish peroxidase.
J Biochem. 1972 Feb;71(2):311-9
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Evidence that peroxidation of lysosomal membranes is initiated by hydroxyl free radicals produced during flavin enzyme activity.
J Biol Chem. 1973 Nov 25;248(22):7792-7
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Free radicals and inflammation: protection of synovial fluid by superoxide dismutase.
Science. 1974 Aug 9;185(4150):529-31
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Superoxide dismutase activity of low molecular weight Cu2 plus-chelates studied by pulse radiolysis.
FEBS Lett. 1974 Oct 1;47(1):72-5
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Oxidation of ascorbic acid with superoxide anion generated by the xanthine-xanthine oxidase system.
Biochem Biophys Res Commun. 1975 Mar 17;63(2):463-8
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Superoxide dismutases.
Annu Rev Biochem. 1975;44:147-59
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Lipid oxidation in biological membranes. Electron transfer proteins as initiators of lipid autoxidation.
Arch Biochem Biophys. 1975 Nov;171(1):292-304
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Fifth Stenhous-Williams memorial lecture. Oxygen and the obligate anaerobe.
J Appl Bacteriol. 1976 Jun;40(3):229-44
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Iron overload--clinical and pathologic aspects.
Semin Hematol. 1977 Jan;14(1):89-113
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Modification of superoxide dismutase in rat mammary carcinoma.
Res Commun Chem Pathol Pharmacol. 1977 May;17(1):125-32
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The protective action of superoxide dismutase on metal-ion catalysed peroxidation of phospholipids.
Biochem Biophys Res Commun. 1977 Jul 11;77(1):379-86
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Regulation of hydrogen peroxide in eye humors. Effect of 3-amino-1H-1,2,4-triazole on catalase and glutathione peroxidase of rabbit eye.
Biochim Biophys Acta. 1977 May 26;497(3):641-51
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Liposome oxidation and erythrocyte lysis by enzymically generated superoxide and hydrogen peroxide.
J Biol Chem. 1977 Oct 10;252(19):6721-8
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Superoxide-dependent production of hydroxyl radical catalyzed by iron-EDTA complex.
FEBS Lett. 1978 Feb 1;86(1):139-42
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Oxygen-dependent microbial killing by phagocytes (first of two parts).
N Engl J Med. 1978 Mar 23;298(12):659-68
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Oxygen-dependent microbial killing by phagocytes (second of two parts).
N Engl J Med. 1978 Mar 30;298(13):721-5
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Iron and infection.
Microbiol Rev. 1978 Mar;42(1):45-66
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Hydroperoxide metabolism in mammalian organs.
Physiol Rev. 1979 Jul;59(3):527-605
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Hydroxyl radical production in a purified NADPH--cytochrome c (P-450) reductase system.
Arch Biochem Biophys. 1979 Apr 1;193(2):373-8
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Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals.
Biochem J. 1979 Aug 15;182(2):625-8
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Formation of hydroxyl radicals from hydrogen peroxide and iron salts by superoxide- and ascorbate-dependent mechanisms: relevance to the pathology of rheumatoid disease.
Clin Sci (Lond). 1983 Jun;64(6):649-53
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Effect of ferritin-containing fractions with different iron loading on lipid peroxidation.
Biochem J. 1983 Feb 1;209(2):557-60
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Inhibition of microsomal oxidation of alcohols and of hydroxyl-radical-scavenging agents by the iron-chelating agent desferrioxamine.
Biochem J. 1983 Jan 15;210(1):107-13
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Lactoferrin-catalysed hydroxyl radical production. Additional requirement for a chelating agent.
Biochem J. 1983 Jan 15;210(1):15-9
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Oxygen metabolism of Streptococcus mutans: uptake of oxygen and release of superoxide and hydrogen peroxide.
J Bacteriol. 1983 Jun;154(3):1236-44
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Superoxide-dependent formation of hydroxyl radical catalyzed by transferrin.
FEBS Lett. 1983 Jun 27;157(1):197-9
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Ocular toxicity of high-dose intravenous desferrioxamine.
Lancet. 1983 Jul 23;2(8343):181-4
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Superoxide radical: an endogenous toxicant.
Annu Rev Pharmacol Toxicol. 1983;23:239-57
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Mechanisms of lipid peroxide formation in animal tissues.
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Lipid peroxidation: its measurement, occurrence, and significance in animal tissues.
Adv Gerontol Res. 1967;2:355-403
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Intracellular mechanisms for the decomposition of a lipid peroxide. I. Decomposition of a lipid peroxide by metal ions, heme compounds, and nucleophiles.
Can J Biochem. 1969 May;47(5):485-92
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Lipid peroxide formation in microsomes. The role of non-haem iron.
Biochem J. 1969 Jun;113(2):325-32
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Vitamin C and iron.
N Engl J Med. 1981 Jan 15;304(3):170-1
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Clinical consequences of acquired transfusional iron overload in adults.
N Engl J Med. 1981 Feb 5;304(6):319-24
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Oxidation of arachidonic acid in micelles by superoxide and hydrogen peroxide.
J Biol Chem. 1981 Jan 10;256(1):260-5
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Lactoferrin enhances hydroxyl radical production by human neutrophils, neutrophil particulate fractions, and an enzymatic generating system.
J Clin Invest. 1981 Feb;67(2):352-60
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Chromosome-damaging activity of ferritin and its relation to chelation and reduction of iron.
Cancer Res. 1981 May;41(5):1628-36
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Free radicals and singlet oxygen scavengers: reaction of a peroxy-radical with beta-carotene, diphenyl furan and 1,4-diazobicyclo (2,2,2)-octane.
Biochem Biophys Res Commun. 1981 Feb 27;98(4):901-6
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Manganese, superoxide dismutase, and oxygen tolerance in some lactic acid bacteria.
J Bacteriol. 1981 Jun;146(3):928-36
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Antitumor effect of a copper coordination compound with superoxide dismutase-like activity.
J Natl Cancer Inst. 1981 Jun;66(6):1077-81
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Involvement of singlet oxygen in biochemical systems.
Bull Eur Physiopathol Respir. 1981;17 Suppl:31-41
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Role of iron and ethylenediaminetetraacetic acid in the bactericidal activity of a superoxide anion-generating system.
Arch Biochem Biophys. 1981 May;208(2):512-9
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Thiobarbituric acid-reactivity following iron-dependent free-radical damage to amino acids and carbohydrates.
FEBS Lett. 1981 Jun 15;128(2):343-6
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Formation of thiobarbituric-acid-reactive substance from deoxyribose in the presence of iron salts: the role of superoxide and hydroxyl radicals.
FEBS Lett. 1981 Jun 15;128(2):347-52
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Caeruloplasmin: physiological and pathological perspectives.
Crit Rev Clin Lab Sci. 1981;14(4):257-329
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Photosensitized oxidation in the ocular lens: evidence for photosensitizers endogenous to the human lens.
Photochem Photobiol. 1981 Jun;33(6):869-74
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Studies on the properties of the singlet oxygen-like factor produced during lipid peroxidation.
Biochim Biophys Acta. 1978 Mar 30;528(3):497-506
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The biology of oxygen radicals.
Science. 1978 Sep 8;201(4359):875-80
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Copper-induced generation of superoxide in human red cell membrane.
Biochem Biophys Res Commun. 1978 Jul 28;83(2):587-92
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Superoxide-dependent formation of hydroxyl radicals in the presence of iron chelates: is it a mechanism for hydroxyl radical production in biochemical systems?
FEBS Lett. 1978 Aug 15;92(2):321-6
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Non-specific serum iron in thalassaemia: an abnormal serum iron fraction of potential toxicity.
Br J Haematol. 1978 Oct;40(2):255-63
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Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts. Its role in degradation of hyaluronic acid by a superoxide-generating system.
FEBS Lett. 1978 Dec 15;96(2):238-42
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The effect of iron on the distribution of superoxide and hydroxyl radicals as seen by spin trapping and on the superoxide dismutase assay.
Photochem Photobiol. 1978 Oct-Nov;28(4-5):693-5
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Role of superoxide dismutase in cancer: a review.
Cancer Res. 1979 Apr;39(4):1141-9
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Spin trapping of superoxide.
Mol Pharmacol. 1979 Sep;16(2):676-85
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Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine.
Biochem J. 1979 Nov 15;184(2):469-72
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Mitochondrial iron not bound in heme and iron-sulfur centers. Estimation, compartmentation and redox state.
Biochim Biophys Acta. 1980 Feb 8;589(2):162-75
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A new method for the detection of hydroxyl radical production by phagocytic cells.
Biochim Biophys Acta. 1980 Feb 21;628(1):90-7
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Effect of oxygen-derived free radicals on hyaluronic acid.
Arthritis Rheum. 1980 Apr;23(4):455-63
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Growth-modulating tripeptide (glycylhistidyllysine): association with copper and iron in plasma, and stimulation of adhesiveness and growth of hepatoma cells in culture by tripeptide-metal ion complexes.
J Cell Physiol. 1980 Feb;102(2):129-39
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Iron transport and storage proteins.
Annu Rev Biochem. 1980;49:357-93
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Differential sensitivity of tumor cells to externally generated hydrogen peroxide. Role of glutathione and related enzymes.
Cancer Biochem Biophys. 1979;3(3):135-41
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Superoxide-dependent formation of hydroxyl radicals in the presence of thiol compounds.
FEBS Lett. 1982 Feb 8;138(1):33-6
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Oxygen toxicity in Streptococcus sanguis. The relative importance of superoxide and hydroxyl radicals.
J Biol Chem. 1982 Apr 25;257(8):4046-51
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Enhanced production of hydroxyl radicals by the xanthine-xanthine oxidase reaction in the presence of lactoferrin.
Biochim Biophys Acta. 1982 Mar 15;715(1):116-20
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The significance of iron in infection.
Rev Infect Dis. 1981 Nov-Dec;3(6):1127-38
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Collagen degradation in an experimental inflammatory lesion: studies on the role of the macrophage.
Acta Biol Med Ger. 1981;40(10-11):1625-36
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The role of superoxide in xanthine oxidase-induced autooxidation of linoleic acid.
J Biol Chem. 1982 Jul 25;257(14):8343-7
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Reactions of ferrioxamine and desferrioxamine with the hydroxyl radical.
Chem Biol Interact. 1982 Jul 15;41(1):75-81
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Interaction of oxygen and oxy-radicals with carotenoids.
J Natl Cancer Inst. 1982 Jul;69(1):205-10
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Treatment of dialysis osteomalacia with desferrioxamine.
Lancet. 1982 Aug 14;2(8294):343-5
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Production of superoxide, hydrogen peroxide and hydroxyl radicals by phagocytic cells: a cause of chronic inflammatory disease?
Cell Biol Int Rep. 1982 Jun;6(6):529-42
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Superoxide-dependent formation of hydroxyl radicals from NADH and NADPH in the presence of iron salts.
FEBS Lett. 1982 Jun 1;142(1):39-41
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Thiol-dependent lipid peroxidation.
Biochem Biophys Res Commun. 1982 Jul 16;107(1):279-85
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Iron-induced DNA damage and synthesis in isolated rat liver nuclei.
Biochem J. 1982 Aug 1;205(2):321-9
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Stimulated human phagocytes produce cytogenetic changes in cultured mammalian cells.
N Engl J Med. 1983 Jan 6;308(1):26-30
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Reaction of iron-EDTA chelates with the superoxide radical.
Arch Biochem Biophys. 1982 Oct 1;218(1):174-8
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Superoxide-dependent formation of hydroxyl radicals and lipid peroxidation in the presence of iron salts. Detection of 'catalytic' iron and anti-oxidant activity in extracellular fluids.
Biochem J. 1982 Sep 15;206(3):605-9
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Spontaneous oxygen radical generation by sickle erythrocytes.
J Clin Invest. 1982 Dec;70(6):1253-9
PMID: 6294138
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Factors which affect DNA strand breakage in human leukocytes exposed to a tumor promoter, phorbol myristate acetate.
Can J Physiol Pharmacol. 1982 Nov;60(11):1359-66
PMID: 6295575