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PMID: 6323164 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Structure and function of the intercistronic regulatory deoC-deoA element of Escherichia coli K-12.

The EMBO journal ·Vol. 3 ·No. 1 ·1984-01-00 ·Pages 179-83

Valentin-Hansen P, Hammer-Jespersen K, Boetius F, Svendsen I

Abstract

The deoC-deoA intercistronic region from Escherichia coli has been characterized by DNA and protein sequencing. This region consists of 129 bp and includes a regulatory element, which has also been found in other operons containing large intercistronic regions. Our results suggest that the regulatory element functions as a transcriptional attenuator, and therefore it seems likely that the primary role of this element is to effect differential expression of operon genes. Furthermore, we have unambiguously shown that the initiation codon for the deoA gene is UUG.

MeSH Terms

Amino Acid Sequence Bacterial Proteins/genetics Base Sequence Escherichia coli/genetics Genes Genes, Bacterial Genes, Regulator Operon Plasmids

Chemicals

Bacterial Proteins

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Valentin-Hansen P

Hammer-Jespersen K

Boetius F

Svendsen I

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29 references, click to expand

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Article Info

Journal

The EMBO journal

Abbr.

EMBO J

ISSN

0261-4189

Published

1984-01-00

Pages

179-83

Language

English

Region

England

NLM ID

8208664

PMCID

PMC557317

Subset

Databases

GENBANK

X00314

External Links

PubMed source PMC Full Text View journal details

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Structure and function of the intercistronic regulatory deoC-deoA element of Escherichia coli K-12.

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