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PMID: 6306579 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Nucleotide sequence of a segment of Drosophila mitochondrial DNA that contains the genes for cytochrome c oxidase subunits II and III and ATPase subunit 6.

Nucleic acids research ·Vol. 11 ·No. 12 ·1983-06-25 ·Pages 4211-27

Clary DO, Wolstenholme DR

Abstract

The nucleotide sequence of a segment of the mtDNA molecule of Drosophila yakuba has been determined, within which have been identified the genes for tRNAleuUUR, cytochrome c oxidase subunit II (COII), tRNAlys, tRNAasp, URFA6L, ATPase subunit 6 (ATPase6), cytochrome c oxidase subunit III (COIII) and tRNAgly. The genes are arranged in the order given and all are transcribed from the same strand of the molecule in a direction opposite to that in which replication proceeds around the molecule. The tRNAlys gene is unusual among mitochondrial tRNAlys genes in that it contains a CTT anticodon. The triplet AGA is used to specify an amino acid in all of the COII, COIII, ATPase6, and URFA6L genes. However, the AGA codons found in these four polypeptide genes correspond in position to codons which specify nine different amino acids, but never arginine, in the equivalent polypeptide gene which have been sequenced from mtDNAs of mouse, yeast and Zea mays.

MeSH Terms
Adenosine Triphosphatases/genetics Animals Base Sequence Codon DNA, Mitochondrial/analysis Drosophila Electron Transport Complex IV/genetics Macromolecular Substances Nucleic Acid Conformation RNA, Transfer/genetics
Chemicals
Codon DNA, Mitochondrial Macromolecular Substances RNA, Transfer Electron Transport Complex IV Adenosine Triphosphatases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Clary D O
Wolstenholme D R
References (35)
35 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/11.12.4211
Published
1983-06-25
Pages
4211-27
Language
English
Region
England
NLM ID
0411011
PMCID
PMC326036
Subset
IM
Grants
NIGMS NIH HHS · GM 18375 · United States
NCRR NIH HHS · RR 07092 · United States
Databases
GENBANK
J01400, J01401, J01402, J01403, J01406, J01408, V01521, X00563, X03240
External Links
PubMed source DOI: 10.1093/nar/11.12.4211 PMC Full Text View journal details
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