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PMID: 6306578 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Sequence of the C. elegans transposable element Tc1.

Nucleic acids research ·Vol. 11 ·No. 12 ·1983-06-25 ·Pages 4201-9

Rosenzweig B, Liao LW, Hirsh D

Abstract

The complete nucleotide sequence was determined for Tc1, a transposable element in the nematode Caenorhabditis elegans. The 1610-base-pair element terminates in 54-base-pair perfect inverted repeats and is flanked by a 2-base-pair duplication of the target sequence. The Tc1 sequence contains two long open reading frames on the same DNA strand but in different translational reading frames. The positions of transcriptional control sequences suggest that a single transcript is made, which could produce two polypeptides, 273 and 112 amino acids in length. These features, i.e. terminal repeats, target site duplication and open reading frames, make Tc1 similar to transposable elements from other species.

MeSH Terms
Animals Base Sequence Caenorhabditis/genetics DNA Restriction Enzymes/metabolism DNA Transposable Elements
Chemicals
DNA Transposable Elements DNA Restriction Enzymes
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Rosenzweig B
Liao L W
Hirsh D
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31 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/11.12.4201
Published
1983-06-25
Pages
4201-9
Language
English
Region
England
NLM ID
0411011
PMCID
PMC326035
Subset
IM
Grants
NIGMS NIH HHS · GM26515 · United States
Databases
GENBANK
K01135, K01136
External Links
PubMed source DOI: 10.1093/nar/11.12.4201 PMC Full Text View journal details
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