Home LiteratureArticle Details
PMID: 7099972 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

A design for computer nucleic-acid-sequence storage, retrieval, and manipulation.

Nucleic acids research ·Vol. 10 ·No. 9 ·1982-05-11 ·Pages 3013-24

Schneider TD, Stormo GD, Haemer JS, Gold L

Abstract

We have designed and built a data-base system for the storage of nucleic-acid sequences. The system consists of a data base ("the library") and software that manages and provides access to that data base ("the Librarian").

MeSH Terms
Base Sequence Computers Data Collection/methods Information Systems
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Schneider T D
Stormo G D
Haemer J S
Gold L
References (40)
40 references, click to expand
  1. Cytoplasmic site synthesis of chloroplast aminoacyl-tRNA synthetases in Euglena gracilis.
    FEBS Lett. 1973 Dec 15;38(1):70-4 PMID: 4204052
  2. Sequencing of 16S--23S spacer in a ribosomal RNA operon of Euglena gracilis chloroplast DNA reveals two tRNA genes.
    Nature. 1980 Aug 28;286(5776):908-10 PMID: 6774264
  3. Maize chloroplast DNA fragment encoding the large subunit of ribulosebisphosphate carboxylase.
    Proc Natl Acad Sci U S A. 1977 Dec;74(12):5487-91 PMID: 16592473
  4. Endonuclease recognition sites mapped on Zea mays chloroplast DNA.
    Proc Natl Acad Sci U S A. 1976 Dec;73(12):4309-13 PMID: 16592373
  5. The Zea mays mitochondrial gene coding cytochrome oxidase subunit II has an intervening sequence and does not contain TGA codons.
    Cell. 1981 Nov;26(3 Pt 1):315-23 PMID: 6276012
  6. Nucleotide sequence of genes coding for tRNAPhe and tRNATyr from a repeating unit of X. laevis DNA.
    Cell. 1980 Feb;19(2):345-53 PMID: 7357612
  7. Hybridization of maize chloroplast DNA with transfer ribonucleic acids.
    Biochemistry. 1976 Sep 7;15(18):4105-9 PMID: 963025
  8. rII cistrons of bacteriophage T4. DNA sequence around the intercistronic divide and positions of genetic landmarks.
    J Mol Biol. 1981 Jul 5;149(3):337-76 PMID: 6273585
  9. Primary structure of three leucine transfer RNAs from bean chloroplast.
    Biochem Biophys Res Commun. 1980 Jan 15;92(1):102-8 PMID: 7356445
  10. Computer analysis of nucleic acids and proteins.
    Methods Enzymol. 1980;65(1):595-609 PMID: 6154871
  11. Nucleic acid sequence bank.
    Science. 1980 Sep 12;209(4462):1182 PMID: 7403878
  12. The nucleotide sequence of the maize and spinach chloroplast isoleucine transfer RNA encoded in the 16S to 23S rDNA spacer.
    Nucleic Acids Res. 1982 Mar 11;10(5):1653-9 PMID: 6917975
  13. Compilation of tRNA sequences.
    Nucleic Acids Res. 1981 Jan 10;9(1):r1-23 PMID: 7208351
  14. Analysis of a drosophila tRNA gene cluster: two tRNALeu genes contain intervening sequences.
    Cell. 1981 Jan;23(1):251-9 PMID: 6783316
  15. Structure and processing of yeast precursor tRNAs containing intervening sequences.
    Nature. 1978 Aug 3;274(5670):438-45 PMID: 353564
  16. Nucleic acid sequences: data bank.
    Science. 1980 Dec 5;210(4474):1074 PMID: 6893759
  17. Nucleotide sequence of a mutant eukaryotic gene: the yeast tyrosine-inserting ochre suppressor SUP4-o.
    Proc Natl Acad Sci U S A. 1977 Dec;74(12):5453-7 PMID: 341157
  18. The sites of transcription and translation for Euglena chloroplastic aminoacyl-tRNA synthetases.
    Proc Natl Acad Sci U S A. 1974 May;71(5):1910-4 PMID: 4525469
  19. Transfer ribonucleic acid genes in the chloroplast deoxyribonucleic acid of pea leaves.
    Biochemistry. 1980 Dec 23;19(26):5973-81 PMID: 6907019
  20. Restriction endonuclease map of the chloroplast DNA of Chlamydomonas reinhardii.
    J Mol Biol. 1978 Dec 25;126(4):597-617 PMID: 745241
  21. Sequencing of the 16S-23S spacer in a ribosomal RNA operon of Zea mays chloroplast DNA reveals two split tRNA genes.
    Cell. 1981 Jul;25(1):203-13 PMID: 7023695
  22. The nucleotide sequences of two tRNAAsn genes from tobacco chloroplasts.
    Nucleic Acids Res. 1981 Nov 11;9(21):5601-7 PMID: 6273800
  23. The revolution in computers and electronics.
    Science. 1982 Feb 12;215(4534):751-3 PMID: 17747835
  24. Post-translational transport into intact chloroplasts of a precursor to the small subunit of ribulose-1,5-bisphosphate carboxylase.
    Proc Natl Acad Sci U S A. 1978 Dec;75(12):6110-4 PMID: 16592597
  25. Detection of specific sequences among DNA fragments separated by gel electrophoresis.
    J Mol Biol. 1975 Nov 5;98(3):503-17 PMID: 1195397
  26. Isolation of yeast tRNALeu genes. DNA sequence of a cloned tRNALeu3 gene.
    J Biol Chem. 1979 Dec 25;254(24):12306-9 PMID: 387786
  27. In vitro transcription and processing of a yeast tRNA gene containing an intervening sequence.
    Cell. 1979 Jun;17(2):399-406 PMID: 378410
  28. Fractionation and identification of spinach chloroplast transfer RNAs and mapping of their genes on the restriction map of chloroplast DNA.
    Gene. 1979 Aug;6(4):285-306 PMID: 499808
  29. Information content in the chloroplast DNA.
    Symp Soc Exp Biol. 1970;24:147-79 PMID: 4930349
  30. Steps toward computer analysis of nucleotide sequences.
    Science. 1980 Sep 19;209(4463):1322-8 PMID: 6251542
  31. The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites.
    Proc Natl Acad Sci U S A. 1974 Apr;71(4):1342-6 PMID: 4598299
  32. A precursor to a minor species of yeast tRNASer contains an intervening sequence.
    Cell. 1979 Sep;18(1):11-26 PMID: 389430
  33. Sequence of the intron and flanking exons of the mitochondrial 21S rRNA gene of yeast strains having different alleles at the omega and rib-1 loci.
    Cell. 1980 May;20(1):185-97 PMID: 6156002
  34. Structure of yeast phenylalanine-tRNA genes: an intervening DNA segment within the region coding for the tRNA.
    Proc Natl Acad Sci U S A. 1978 Jan;75(1):190-4 PMID: 343104
  35. An altered chloroplast ribosomal protein in ery-M1 mutants of Chlamydomonas reinhardi.
    Mol Gen Genet. 1974;132(2):119-29 PMID: 4421915
  36. Sequencing end-labeled DNA with base-specific chemical cleavages.
    Methods Enzymol. 1980;65(1):499-560 PMID: 6246368
  37. Mendelian and uniparental alterations in erythromycin binding by plastid ribosomes.
    Science. 1971 Nov 12;174(4010):707-9 PMID: 5123420
  38. Euglena gracilis chloroplast ribosomal RNA transcription units. II. Nucleotide sequence homology between the 16 S--23 S ribosomal RNA spacer and the 16 S ribosomal RNA leader regions.
    J Biol Chem. 1980 Nov 25;255(22):10997-1003 PMID: 6253497
  39. Transcription and processing of intervening sequences in yeast tRNA genes.
    Cell. 1978 Jun;14(2):221-36 PMID: 352537
  40. A gene coding for tRNA is located near 5' terminus of 16S rRNA gene in Zea mays chloroplast genome.
    Proc Natl Acad Sci U S A. 1981 Aug;78(8):4748-52 PMID: 16593071
Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/10.9.3013
Published
1982-05-11
Pages
3013-24
Language
English
Region
England
NLM ID
0411011
PMCID
PMC320671
Subset
IM
Grants
NIGMS NIH HHS · 1 R01 GM28755 · United States
NIGMS NIH HHS · 5 R01 GM19963 · United States
NIGMS NIH HHS · 5 T32 GM07385 · United States
External Links
PubMed source DOI: 10.1093/nar/10.9.3013 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2