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PMID: 6290870 Published · ppublish English Journal Article

Human gene (c-fes) related to the onc sequences of Snyder-Theilen feline sarcoma virus.

Molecular and cellular biology ·Vol. 2 ·No. 8 ·1982-08-00 ·Pages 1014-9

Franchini G, Gelmann EP, Dalla-Favera R, Gallo RC, Wong-Staal F

Abstract

The onc gene (v-fes) of the acutely transforming feline sarcoma virus (Snyder-Theilen strain) has homologous cellular sequences (c-fes) in all vertebrate species, including humans. We isolated from a human DNA library recombinant phages containing overlapping c-fes sequences. The human c-fes locus spans a region of 3.4 kilobases and contains 1.4 kilobases of DNA homologous to the viral onc sequence interspersed with three intervening sequences.

MeSH Terms
Bacteriophage lambda/genetics Base Sequence DNA/genetics DNA Restriction Enzymes DNA, Recombinant DNA, Viral/genetics Defective Viruses/genetics Genes Genes, Viral Humans Nucleic Acid Hybridization Retroviridae/genetics Sarcoma Viruses, Feline/genetics
Chemicals
DNA, Recombinant DNA, Viral DNA DNA Restriction Enzymes
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Franchini G
Gelmann E P
Dalla-Favera R
Gallo R C
Wong-Staal F
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31 references, click to expand
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Article Info
Journal
Molecular and cellular biology
Abbr.
Mol Cell Biol
ISSN
0270-7306
DOI
10.1128/mcb.2.8.1014-1019.1982
Published
1982-08-00
Pages
1014-9
Language
English
Region
United States
NLM ID
8109087
PMCID
PMC369889
Subset
IM
External Links
PubMed source DOI: 10.1128/mcb.2.8.1014-1019.1982 PMC Full Text View journal details
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