Diminished effect of sympathetic nerve stimulation in cats pretreated with 5-hydroxydopa; formation and liberation of false adrenergic transmitters.

Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie ·Vol. 259 ·No. 1 ·1967-00-00 ·Pages 17-33

Thoenen H, Haefely W, Gey KF, Hürlimann A

Abstract

暂无摘要

MeSH Terms

Animals Blood Pressure/drug effects Catecholamines/pharmacology Cats Chromatography, Ion Exchange Chromatography, Paper Dihydroxyphenylalanine Female Heart/drug effects Iris/drug effects,innervation,metabolism Male Myocardium/analysis,metabolism Nictitating Membrane/drug effects,innervation,metabolism Norepinephrine/metabolism,pharmacology Perfusion Spleen/analysis,drug effects,innervation,metabolism Sympathetic Nervous System/physiology Synaptic Transmission Tritium

Chemicals

Catecholamines Tritium Dihydroxyphenylalanine Norepinephrine

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Thoenen H

Haefely W

Gey K F

Hürlimann A

References (14)

14 references, click to expand

A hypothesis for the mode of action of alpha-methyldopa in relieving hypertension.
J Pharm Pharmacol. 1963 Apr;15:221-4 PMID: 14025624
Biochemical aspects of release of norepinephrine and other amines from sympathetic nerve endings.
Pharmacol Rev. 1966 Mar;18(1):513-23 PMID: 5904165
The effect of stimulation of sympathetic nerves in the cat treated with reserpine, alpha-methyldopa and alpha-methylmetatyrosine.
Br J Pharmacol Chemother. 1966 Jan;26(1):172-85 PMID: 5920649
Liberation of alpha-methyldopamine as a "false" sympathetic transmitter after pretreatment of cats with alpha-methyldopa and disulfiram.
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1967;258(2):181-96 PMID: 4385111
Adrenergic transmitter changes and response to sympathetic nerve stimulation after differing pretreatment with alpha-methyldopa.
Br J Pharmacol Chemother. 1967 Sep;31(1):105-19 PMID: 6055245
In-vivo decarboxylation of alpha-methyl DOPA and alpha-methyl metatyrosine.
Acta Physiol Scand. 1962 Jan;54:87-94 PMID: 13876658
PROPERTIES OF NOREPINEPHRINE STORAGE PARTICLES OF THE RAT HEART.
J Pharmacol Exp Ther. 1963 Dec;142:299-305 PMID: 14098325
The release of protein from the stimulated adrenal medulla.
Biochem J. 1965 Dec;97(3):40C-41C PMID: 5881651
RELEASE BY SYMPATHETIC STIMULATION OF ALPHA-METHYLNORADRENALINE STORED IN THE HEART AFTER ADMINISTRATION OF ALPHA-METHYLDOPA.
Experientia. 1963 Dec 15;19:658-9 PMID: 14099879
Storage particles in noradrenergic tissues.
Pharmacol Rev. 1966 Mar;18(1):425-32 PMID: 5904157
A method for the fluorimetric determination of adrenaline and noradrenaline in tissues.
Acta Physiol Scand. 1958 Dec 15;44(3-4):273-92 PMID: 13617023
THE ESTIMATION OF SMALL QUANTITIES OF 3,4-DIHYDROXYPHENYLETHYLAMINE IN TISSUES.
Br J Pharmacol Chemother. 1965 Apr;24:538-48 PMID: 14320868
[EFFECTS OF PHENOXYBENZAMINE, PHENTOLAMINE AND AZAPETINE ON ADRENERGIC SYNAPSES OF THE CAT SPLEEN. BLOCKADE OF ALPHA-ADRENERGIC RECEPTORS AND INHIBITION OF RE-UPTAKE OF NEURALLY RELEASED NORADRENALINE].
Helv Physiol Pharmacol Acta. 1964;22:148-61 PMID: 14246442
The chemorelease of norepinephrine from mouse hearts. Structure-activity relationships. I. Sympathomimetic and related amines.
J Med Chem. 1966 May;9(3):273-80 PMID: 5960887

Article Info

Journal

Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie

Abbr.

Naunyn Schmiedebergs Arch Exp Pathol Pharmakol

DOI

10.1007/BF00538137

Published

1967-00-00

Pages

17-33

Language

English

Region

Germany

NLM ID

0054224

Subset

External Links

PubMed source DOI: 10.1007/BF00538137

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Diminished effect of sympathetic nerve stimulation in cats pretreated with 5-hydroxydopa; formation and liberation of false adrenergic transmitters.

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