Adrenergic transmitter changes and response to sympathetic nerve stimulation after differing pretreatment with alpha-methyldopa.

British journal of pharmacology and chemotherapy ·Vol. 31 ·No. 1 ·1967-09-00 ·Pages 105-19

Haefely W, Hürlimann A, Thoenen H

Abstract

暂无摘要

MeSH Terms

Animals Blood Pressure/drug effects Cats Electric Stimulation Female Heart/drug effects In Vitro Techniques Injections, Intraperitoneal Iris/drug effects Male Methyldopa/administration & dosage,pharmacology Nictitating Membrane/drug effects Norepinephrine/analysis Normetanephrine/analysis Phenoxybenzamine/pharmacology Spleen/drug effects Sympathetic Nervous System/physiology

Chemicals

Normetanephrine Phenoxybenzamine Methyldopa Norepinephrine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Haefely W

Hürlimann A

Thoenen H

References (16)

16 references, click to expand

Hypotensive actions of drugs on unanesthetized normotensive and "metacorticoid" hypertensive rats determined by a direct recording technique.
Arch Int Pharmacodyn Ther. 1965 Apr;154(2):351-63 PMID: 5838340
[Comparative studies on the hypotensive action of alpha-methyldopa and alpha-methyl-m-tyrosine].
Dtsch Med Wochenschr. 1966 Feb 4;91(5):198-205 PMID: 5900997
Autonomic nervous system: newer mechanisms of adrenergic blockade.
Annu Rev Pharmacol. 1966;6:107-28 PMID: 5324847
Diminished effects of sympathetic nerve stimulation in cats pretreated with disulfiram; liberation of dopamine as sympathetic transmitter.
Life Sci. 1965 Nov;4(21):2033-8 PMID: 5866619
Impairment of sympathetic nerve responses by dopa, dopamine and their alpha-methyl analogues.
J Pharm Pharmacol. 1965 Oct;17(10):640-6 PMID: 4379687
Effects of methyldopa (aldomet) on cardiovascular responses to adrenaline, noradrenaline and tyramine in rabbits.
Arch Int Pharmacodyn Ther. 1966 Jan;159(1):219-33 PMID: 5920395
The effect of stimulation of sympathetic nerves in the cat treated with reserpine, alpha-methyldopa and alpha-methylmetatyrosine.
Br J Pharmacol Chemother. 1966 Jan;26(1):172-85 PMID: 5920649
Antihypertensive effect of methyldopa in metacorticoid immunosympathectomized rats.
J Pharm Pharmacol. 1967 Jan;19(1):61-2 PMID: 4382180
[A simple method of bloodless measurement of blood pressure and heart rate in rats in acute and chronic experiments].
Helv Physiol Pharmacol Acta. 1966;24(1):58-69 PMID: 5973603
[Demonstration of alpha-methylnoradrenaline in the urine of hypertensive patients treated with alpha-methyldopa].
Klin Wochenschr. 1966 Dec 15;44(24):1412-3 PMID: 5994691
[Qualitatively and quantitatively different effects of alpha-methyldopa treatment on cats according to a dosage scheme].
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A method for the fluorimetric determination of adrenaline and noradrenaline in tissues.
Acta Physiol Scand. 1958 Dec 15;44(3-4):273-92 PMID: 13617023
Actions of the decarboxylase inhibitor, alpha-methyl-3,4-dihydroxyphenylalanine, in the dog.
Nature. 1960 Nov 5;188:502-4 PMID: 13706461
RELEASE BY SYMPATHETIC STIMULATION OF ALPHA-METHYLNORADRENALINE STORED IN THE HEART AFTER ADMINISTRATION OF ALPHA-METHYLDOPA.
Experientia. 1963 Dec 15;19:658-9 PMID: 14099879
EFFECT OF ALPHA-METHYL-DOPA ON MYOCARDIAL CATECHOLAMINES.
Experientia. 1963 Nov 15;19:573-5 PMID: 14101511
SOME OBSERVATIONS ON THE PHARMACOLOGY OF ALPHA-METHYLDOPA.
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Article Info

Journal

British journal of pharmacology and chemotherapy

Abbr.

Br J Pharmacol Chemother

ISSN

0366-0826

DOI

10.1111/j.1476-5381.1967.tb01981.x

Published

1967-09-00

Pages

105-19

Language

English

Region

England

NLM ID

0154627

PMCID

PMC1557288

Subset

External Links

PubMed source DOI: 10.1111/j.1476-5381.1967.tb01981.x PMC Full Text

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Adrenergic transmitter changes and response to sympathetic nerve stimulation after differing pretreatment with alpha-methyldopa.

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