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PMID: 4069981 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Changes of energy metabolism, myosin light chain composition, lactate dehydrogenase isozyme pattern and fibre type distribution of denervated fast-twitch muscle from rabbit after low frequency stimulation.

Pflugers Archiv : European journal of physiology ·Vol. 405 ·No. 3 ·1985-10-00 ·Pages 244-9

Reichmann H, Nix WA

Abstract

The influence of low frequency (8-10 Hz) electrical stimulation on denervated fast-twitch muscle from rabbit was investigated. Prolonged direct stimulation of denervated muscle resulted in higher oxidative enzyme activities. Furthermore, single fibre analyses for succinate dehydrogenase showed a more uniform distribution of activity in stimulated-denervated muscle when compared to normal muscle. As was also the case following stimulation of innervated muscle, glycolytic enzymes were decreased in activity and the LDH-isozyme pattern was also shifted towards heart type. No change of the myosin light chain pattern could be observed after 56 days of stimulation.

MeSH Terms
Animals Chemical Phenomena Chemistry Electric Stimulation Energy Metabolism Histocytochemistry Isoenzymes L-Lactate Dehydrogenase/metabolism Muscle Denervation Muscles/enzymology,metabolism Myosins/metabolism Rabbits
Chemicals
Isoenzymes L-Lactate Dehydrogenase Myosins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Reichmann H
Nix W A
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33 references, click to expand
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Article Info
Journal
Pflugers Archiv : European journal of physiology
Abbr.
Pflugers Arch
ISSN
0031-6768
DOI
10.1007/BF00582568
Published
1985-10-00
Pages
244-9
Language
English
Region
Germany
NLM ID
0154720
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00582568 View journal details
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