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PMID: 4059036 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Influence of direct low frequency stimulation on contractile properties of denervated fast-twitch rabbit muscle.

Pflugers Archiv : European journal of physiology ·Vol. 405 ·No. 2 ·1985-09-00 ·Pages 141-7

Nix WA, Reichmann H, Schröder MJ

Abstract

A continuous electrical 8 Hz impulse pattern imposed directly via implanted electrodes on denervated fast twitch muscle induced changes in its contractile characteristics. Compared with non-stimulated denervated muscle, stimulated muscle showed slowing of contraction time and improved fatigue resistance. The reaction for succinic dehydrogenase was more intense in the denervated stimulated muscle, indicating an increased capacity of oxidative enzymes. The rate of atrophy was not influenced by stimulation. The 8 Hz frequency pattern is the mediator for these changes in the characteristics of denervated muscles. It demonstrates a comparable effect on innervated muscle. The contralateral normal innervated muscle was also influenced by the electrical stimulation. Contraction time as well as twitch tension were increased. This finding is important when using the normal muscle as intraindividual control.

MeSH Terms
Animals Electric Stimulation Electrodes, Implanted Muscle Contraction Muscle Denervation Muscles/innervation,pathology,physiology Muscular Atrophy/pathology Rabbits
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Nix W A
Reichmann H
Schröder M J
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29 references, click to expand
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Article Info
Journal
Pflugers Archiv : European journal of physiology
Abbr.
Pflugers Arch
ISSN
0031-6768
DOI
10.1007/BF00584535
Published
1985-09-00
Pages
141-7
Language
English
Region
Germany
NLM ID
0154720
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00584535 View journal details
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