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PMID: 4043963 Published · ppublish English Case Reports Journal Article Research Support, Non-U.S. Gov't

A 45,X male with evidence of a translocation of Y euchromatin onto chromosome 15.

Human genetics ·Vol. 71 ·No. 2 ·1985-00-00 ·Pages 150-4

Schempp W, Weber B, Serra A, Neri G, Gal A, Wolf U

Abstract

A 19-year-old male with azoospermia was found to have a 45,X karyotype with additional euchromatic material on 15p. The parents' karyotypes are normal. The cytogenetic data, the positive H-Y-typing, and the presence of Yp-specific restriction fragments detected in the proband's genome by molecular DNA probes suggest that the short arm of the Y chromosome, including part of the centromere, is translocated onto the nucleolus organizer region (NOR) of chromosome 15.

MeSH Terms
Adult Chromatin/genetics Chromosome Banding Chromosomes, Human, 13-15 Euchromatin Humans Karyotyping Male Noonan Syndrome/genetics Nucleolus Organizer Region/ultrastructure Translocation, Genetic Y Chromosome
Chemicals
Chromatin Euchromatin
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Schempp W
Weber B
Serra A
Neri G
Gal A
Wolf U
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25 references, click to expand
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Article Info
Journal
Human genetics
Abbr.
Hum Genet
ISSN
0340-6717
DOI
10.1007/BF00283372
Published
1985-00-00
Pages
150-4
Language
English
Region
Germany
NLM ID
7613873
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00283372 View journal details
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