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PMID: 3550695 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

The complete nucleotide sequence of the ilvGMEDA operon of Escherichia coli K-12.

Nucleic acids research ·Vol. 15 ·No. 5 ·1987-03-11 ·Pages 2137-55

Lawther RP, Wek RC, Lopes JM, Pereira R, Taillon BE, Hatfield GW

Abstract

In this report we present the complete nucleotide sequence of the ilvGMEDA operon of Escherichia coli. This operon contains five genes encoding four of the five enzymes required for the biosynthesis of isoleucine and valine. We identify and describe the coding regions for these five structural genes and the structural and functional features of the flanking and internal regulatory regions of this operon. This new information contributes to a more complete understanding of the overall control of the biosynthesis of isoleucine and valine.

MeSH Terms
Amino Acid Sequence Base Sequence Escherichia coli/genetics Genes Genes, Bacterial Isoleucine/biosynthesis Nucleic Acid Conformation Operon Transcription, Genetic Valine/biosynthesis
Chemicals
Isoleucine Valine
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Lawther R P
Wek R C
Lopes J M
Pereira R
Taillon B E
Hatfield G W
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/15.5.2137
Published
1987-03-11
Pages
2137-55
Language
English
Region
England
NLM ID
0411011
PMCID
PMC340622
Subset
IM
Grants
NIGMS NIH HHS · GM24330 · United States
NIGMS NIH HHS · GM28021 · United States
Corrections
ErratumIn
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External Links
PubMed source DOI: 10.1093/nar/15.5.2137 PMC Full Text View journal details
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