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PMID: 3299029 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Shiga and Shiga-like toxins.

Microbiological reviews ·Vol. 51 ·No. 2 ·1987-06-00 ·Pages 206-20

O'Brien AD, Holmes RK

Abstract

暂无摘要

MeSH Terms
Animals Bacterial Toxins/genetics,isolation & purification,pharmacology Escherichia coli Humans Shiga Toxins Shigella
Chemicals
Bacterial Toxins Shiga Toxins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
O'Brien A D
Holmes R K
References (101)
101 references, click to expand
  1. Pathogenesis of Shigella diarrhea. VII. Evidence for a cell membrane toxin receptor involving beta1 leads to 4-linked N-acetyl-D-glucosamine oligomers.
    J Exp Med. 1977 Aug 1;146(2):535-46 PMID: 327017
  2. Immunization with Shigella dysenteriae type 1: evaluation of antitoxic immunity in prevention of experimental disease in rhesus monkeys (Macaca mulatta).
    J Infect Dis. 1977 Sep;136(3):416-21 PMID: 409782
  3. Vero response to a cytotoxin of Escherichia coli.
    Infect Immun. 1977 Dec;18(3):775-9 PMID: 338490
  4. Hemolytic-uremic syndrome after shigellosis. Relation to endotoxemia and circulating immune complexes.
    N Engl J Med. 1978 Apr 27;298(17):927-33 PMID: 642973
  5. Haemolytic-uraemic syndrome complicating shigella dystentery in south Indian children.
    Br Med J. 1978 Jun 10;1(6126):1518-21 PMID: 350345
  6. Comparative studies of five heat-labile toxic products of Escherichia coli.
    Infect Immun. 1978 Dec;22(3):644-8 PMID: 215549
  7. Isolation and characterization of Shigella shigae cytotoxin.
    J Biol Chem. 1980 Jan 10;255(1):284-9 PMID: 7350160
  8. Inhibition of protein synthesis in intact HeLa cells by Shigella dysenteriae 1 toxin.
    Infect Immun. 1980 Jul;29(1):98-107 PMID: 6156915
  9. Inhibition of protein synthesis by Shiga toxin: activation of the toxin and inhibition of peptide elongation.
    FEBS Lett. 1980 Aug 11;117(1):84-8 PMID: 6893307
  10. Characterization of Shigella dysenteriae 1 (Shiga) toxin purified by anti-Shiga toxin affinity chromatography.
    Infect Immun. 1980 Oct;30(1):170-9 PMID: 7002787
  11. Quantitative microtiter cytotoxicity assay for Shigella toxin.
    J Clin Microbiol. 1980 Sep;12(3):361-6 PMID: 7012172
  12. Detection of Vero cytotoxic strains of Escherichia coli isolated from diseased animals.
    Natl Inst Anim Health Q (Tokyo). 1980 Fall;20(3):116-7 PMID: 7019731
  13. Subunit structure of Shigella cytotoxin.
    J Biol Chem. 1981 Aug 25;256(16):8732-8 PMID: 7021550
  14. The cytotoxic activity of Shigella toxin. Evidence for catalytic inactivation of the 60 S ribosomal subunit.
    J Biol Chem. 1981 Aug 25;256(16):8739-44 PMID: 6894922
  15. Shigella sonnei plasmids: evidence that a large plasmid is necessary for virulence.
    Infect Immun. 1981 Oct;34(1):75-83 PMID: 6271687
  16. Interaction of Shigella shigae cytotoxin with receptors on sensitive and insensitive cells.
    J Recept Res. 1980;1(2):199-213 PMID: 6895387
  17. Chronic diarrhea in infants caused by adherent enteropathogenic Escherichia coli.
    J Pediatr. 1982 Mar;100(3):358-61 PMID: 7038073
  18. Immunochemical and cytotoxic activities of Shigella dysenteriae 1 (shiga) and shiga-like toxins.
    Infect Immun. 1982 Mar;35(3):1151-4 PMID: 7040247
  19. Involvement of a plasmid in the invasive ability of Shigella flexneri.
    Infect Immun. 1982 Mar;35(3):852-60 PMID: 6279518
  20. Vero cytotoxin produced by Escherichia coli strains of animal origin.
    Natl Inst Anim Health Q (Tokyo). 1981 Summer;21(2):68-72 PMID: 7043284
  21. A clinicopathologic study of enterocyte-adherent Escherichia coli: a cause of protracted diarrhea in infants.
    Gastroenterology. 1982 Aug;83(2):441-54 PMID: 7044882
  22. Purification and biological characterization of shiga toxin from Shigella dysenteriae 1.
    Infect Immun. 1982 Jun;36(3):996-1005 PMID: 7047403
  23. Shigella toxin(s): description and role in diarrhea and dysentery.
    Pharmacol Ther. 1981;15(3):403-38 PMID: 7048347
  24. Animal toxicity of Shigella dysenteriae cytotoxin: evidence that the neurotoxic, enterotoxic, and cytotoxic activities are due to one toxin.
    J Immunol. 1983 Jan;130(1):380-4 PMID: 6336624
  25. Production of Shigella dysenteriae type 1-like cytotoxin by Escherichia coli.
    J Infect Dis. 1982 Dec;146(6):763-9 PMID: 6754826
  26. Shigella dysenteriae 1 cytotoxin: periplasmic protein releasable by polymyxin B and osmotic shock.
    Infect Immun. 1983 Jan;39(1):270-4 PMID: 6295958
  27. Hemorrhagic colitis associated with a rare Escherichia coli serotype.
    N Engl J Med. 1983 Mar 24;308(12):681-5 PMID: 6338386
  28. Release of Shiga toxin from Shigella dysenteriae 1 by polymyxin B.
    Infect Immun. 1983 Apr;40(1):425-8 PMID: 6299964
  29. Alterations in the pathogenicity of Escherichia coli K-12 after transfer of plasmid and chromosomal genes from Shigella flexneri.
    Infect Immun. 1983 Mar;39(3):1392-402 PMID: 6341237
  30. Purification and characterization of a Shigella dysenteriae 1-like toxin produced by Escherichia coli.
    Infect Immun. 1983 May;40(2):675-83 PMID: 6341244
  31. Isolation and characterization of monoclonal antibodies to Shiga toxin.
    Infect Immun. 1983 Jul;41(1):430-3 PMID: 6345399
  32. Plasmid-mediated adhesion in enteropathogenic Escherichia coli.
    J Pediatr Gastroenterol Nutr. 1983;2(3):534-8 PMID: 6352891
  33. Pathogenesis of Shigella diarrhea. VIII. Evidence for a translocation step in the cytotoxic action of Shiga toxin.
    J Infect Dis. 1983 Nov;148(5):844-54 PMID: 6355319
  34. Molecular comparison of virulence plasmids in Shigella and enteroinvasive Escherichia coli.
    Ann Microbiol (Paris). 1983 May-Jun;134A(3):295-318 PMID: 6357023
  35. Entry of Shigella dysenteriae toxin into HeLa cells.
    Infect Immun. 1983 Nov;42(2):771-7 PMID: 6358031
  36. Vero cell toxins in Escherichia coli and related bacteria: transfer by phage and conjugation and toxic action in laboratory animals, chickens and pigs.
    J Gen Microbiol. 1983 Oct;129(10):3121-37 PMID: 6418852
  37. Membrane receptors for bacterial toxins.
    Microbiol Rev. 1983 Dec;47(4):596-620 PMID: 6363900
  38. A plasmid of enterohemorrhagic Escherichia coli O157:H7 is required for expression of a new fimbrial antigen and for adhesion to epithelial cells.
    Infect Immun. 1987 Feb;55(2):455-61 PMID: 2879796
  39. Characterization of purified Shiga toxin from Shigella dysenteriae 1.
    Microbiol Immunol. 1986;30(11):1115-27 PMID: 3100915
  40. Phage-associated cytotoxin production by and enteroadhesiveness of enteropathogenic Escherichia coli isolated from infants with diarrhea in West Germany.
    J Infect Dis. 1987 Apr;155(4):707-15 PMID: 3546519
  41. Nucleotide sequence analysis of the structural genes for Shiga-like toxin I encoded by bacteriophage 933J from Escherichia coli.
    Microb Pathog. 1987 Feb;2(2):147-53 PMID: 3333796
  42. Shiga toxin from Shigella dysenteriae 1 inhibits protein synthesis in reticulocyte lysates by inactivation of aminoacyl-tRNA binding.
    Microb Pathog. 1986 Aug;1(4):325-34 PMID: 3334156
  43. The neurotoxin of Shigella dysenteriae (shiga).
    Bacteriol Rev. 1952 Sep;16(3):153-78 PMID: 12987385
  44. The neurotoxin of Shigella shigae. I. Production, purification and properties of the toxin.
    Br J Exp Pathol. 1953 Apr;34(2):202-16 PMID: 13051531
  45. Recombinant nontoxinogenic Vibrio cholerae strains as attenuated cholera vaccine candidates.
    Nature. 1984 Apr 12-18;308(5960):655-8 PMID: 6324005
  46. Enteropathogenic Escherichia coli of classic serotypes associated with infant diarrhea: epidemiology and pathogenesis.
    Epidemiol Rev. 1984;6:31-51 PMID: 6386503
  47. Bacterial toxins: cellular mechanisms of action.
    Microbiol Rev. 1984 Sep;48(3):199-221 PMID: 6436655
  48. Shiga-like toxin-converting phages from Escherichia coli strains that cause hemorrhagic colitis or infantile diarrhea.
    Science. 1984 Nov 9;226(4675):694-6 PMID: 6387911
  49. Sporadic cases of hemorrhagic colitis associated with Escherichia coli O157:H7. Clinical, epidemiologic, and bacteriologic features.
    Ann Intern Med. 1984 Dec;101(6):738-42 PMID: 6388450
  50. Shiga-like cytotoxin production by enteropathogenic Escherichia coli serogroups.
    Infect Immun. 1985 Jan;47(1):335-7 PMID: 3880727
  51. Pathogenesis of Shigella diarrhea. IX. Simplified high yield purification of Shigella toxin and characterization of subunit composition and function by the use of subunit-specific monoclonal and polyclonal antibodies.
    J Exp Med. 1984 Dec 1;160(6):1767-81 PMID: 6392471
  52. Shiga-like toxin production from Escherichia coli associated with calf diarrhoea.
    Vet Rec. 1985 Feb 23;116(8):217-8 PMID: 3885557
  53. Colonization of chicken cecae by Escherichia coli associated with hemorrhagic colitis.
    Appl Environ Microbiol. 1985 Feb;49(2):310-5 PMID: 3885853
  54. Shiga toxin--an expanding role in the pathogenesis of infectious diseases.
    J Infect Dis. 1985 May;151(5):766-71 PMID: 3886803
  55. The association between idiopathic hemolytic uremic syndrome and infection by verotoxin-producing Escherichia coli.
    J Infect Dis. 1985 May;151(5):775-82 PMID: 3886804
  56. Shigella toxin and the pathogenesis of shigellosis.
    Ciba Found Symp. 1985;112:193-214 PMID: 3847336
  57. Escherichia coli originated from diarrhea of suckling piglets in Taiwan. III. Ability to produce enterotoxin and Vero cytotoxin.
    Kitasato Arch Exp Med. 1984 Sep;57(3):221-6 PMID: 6399335
  58. Ribonuclease activity associated with the 60S ribosome-inactivating proteins ricin A, phytolaccin and Shiga toxin.
    Biochem Biophys Res Commun. 1985 Jul 31;130(2):879-84 PMID: 3839673
  59. Axonally transported Shigella cytotoxin is neuronotoxic.
    J Neuropathol Exp Neurol. 1985 Sep;44(5):496-506 PMID: 2411880
  60. Cloning of Shiga-like toxin structural genes from a toxin converting phage of Escherichia coli.
    Science. 1985 Oct 11;230(4722):179-81 PMID: 2994228
  61. Characterization of monoclonal antibodies against Shiga-like toxin from Escherichia coli.
    Infect Immun. 1985 Dec;50(3):695-700 PMID: 3905611
  62. Diarrhea due to Escherichia coli O157:H7 in the infant rabbit.
    J Infect Dis. 1985 Dec;152(6):1341-3 PMID: 3905989
  63. Experimental infection of infant rabbits with verotoxin-producing Escherichia coli.
    Infect Immun. 1986 Jan;51(1):16-23 PMID: 3510166
  64. Sensitive method for detecting low numbers of verotoxin-producing Escherichia coli in mixed cultures by use of colony sweeps and polymyxin extraction of verotoxin.
    J Clin Microbiol. 1985 Oct;22(4):614-9 PMID: 3908473
  65. Cloning of genes that encode a new heat-labile enterotoxin of Escherichia coli.
    J Bacteriol. 1986 Feb;165(2):348-52 PMID: 3511028
  66. Pathogenesis of shigella diarrhea: evidence for an N-linked glycoprotein shigella toxin receptor and receptor modulation by beta-galactosidase.
    J Infect Dis. 1986 Feb;153(2):238-48 PMID: 3003205
  67. Infection of gnotobiotic pigs with an Escherichia coli O157:H7 strain associated with an outbreak of hemorrhagic colitis.
    Infect Immun. 1986 Mar;51(3):953-6 PMID: 3512443
  68. Cloning and expression of the genes specifying Shiga-like toxin production in Escherichia coli H19.
    J Bacteriol. 1986 May;166(2):375-9 PMID: 3009393
  69. The relation between production of cytotoxin and clinical features in shigellosis.
    J Infect Dis. 1986 Jul;154(1):149-55 PMID: 3519788
  70. Pathogenesis of shigella diarrhea. XI. Isolation of a shigella toxin-binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide.
    J Exp Med. 1986 Jun 1;163(6):1391-404 PMID: 3519828
  71. Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities.
    Infect Immun. 1986 Jul;53(1):135-40 PMID: 3522426
  72. Enzyme-linked immunosorbent assay for shigella toxin.
    J Clin Microbiol. 1986 Jul;24(1):65-8 PMID: 3522627
  73. Production of Shiga-like toxin by Escherichia coli.
    J Infect Dis. 1986 Aug;154(2):338-41 PMID: 3522760
  74. Pathogenesis of Shigella diarrhea: rabbit intestinal cell microvillus membrane binding site for Shigella toxin.
    Infect Immun. 1986 Aug;53(2):372-7 PMID: 3755421
  75. Purification and physicochemical properties of a unique Vero cell cytotoxin from Escherichia coli O157:H7.
    Biochem Biophys Res Commun. 1986 Sep 14;139(2):424-30 PMID: 3533062
  76. Variation in chemical properties and antigenic determinants among type II heat-labile enterotoxins of Escherichia coli.
    Infect Immun. 1986 Nov;54(2):529-36 PMID: 2429930
  77. Production of type II heat-labile enterotoxin by Escherichia coli isolated from food and human feces.
    Infect Immun. 1986 Nov;54(2):587-9 PMID: 3533784
  78. Complete amino acid sequence of Shigella toxin B-chain. A novel polypeptide containing 69 amino acids and one disulfide bridge.
    J Biol Chem. 1986 Oct 25;261(30):13928-31 PMID: 3771511
  79. Colonic dysfunction during shigellosis.
    J Infect Dis. 1986 Nov;154(5):817-24 PMID: 3772163
  80. Morphologic evaluation of the effects of Shiga toxin and E coli Shiga-like toxin on the rabbit intestine.
    Am J Pathol. 1986 Oct;125(1):69-80 PMID: 3535529
  81. Genetics of bacterial enterotoxins.
    Annu Rev Microbiol. 1986;40:577-605 PMID: 3535654
  82. The neurotoxin of Shigella shigae; a comparative study of the effects produced in various laboratory animals.
    Br J Exp Pathol. 1956 Jun;37(3):272-8 PMID: 13342352
  83. THE HEMOLYTIC-UREMIC SYNDROME.
    J Pediatr. 1964 Apr;64:478-91 PMID: 14141006
  84. Observations on the intoxication produced in mice and rabbits by the neurotoxin of Shigella shigae.
    Br J Exp Pathol. 1955 Oct;36(5):439-46 PMID: 13269655
  85. The neurotoxin of Shigella shigae: morphological and functional lesions produced in the central nervous system of rabbits.
    Br J Exp Pathol. 1955 Oct;36(5):447-53 PMID: 13269656
  86. [Hemolytic-uremic syndrome: bilateral necrosis of the renal cortex in acute acquired hemolytic anemia].
    Schweiz Med Wochenschr. 1955 Sep 20;85(38-39):905-9 PMID: 13274004
  87. The action of the thermolabile toxin of Shigella dysenteriae on cells cultivated in vitro.
    Br J Exp Pathol. 1960 Apr;41:179-89 PMID: 13842077
  88. The response of man to virulent Shigella flexneri 2a.
    J Infect Dis. 1969 Mar;119(3):296-9 PMID: 5780532
  89. The pathogenesis of Shigella diarrhea. I. Enterotoxin production by Shigella dysenteriae I.
    J Clin Invest. 1972 May;51(5):1212-8 PMID: 4560429
  90. Pathogenesis of Shigella dysenteriae 1 (Shiga) dysentery.
    J Infect Dis. 1973 Mar;127(3):261-70 PMID: 4631877
  91. Serum enterotoxin-neutralizing antibody in human shigellosis.
    Nat New Biol. 1973 Jan 3;241(105):31-2 PMID: 4572837
  92. Shigellosis due to Shigella dysenteriae. 1. Relative importance of mucosal invasion versus toxin production in pathogenesis.
    J Infect Dis. 1972 Nov;126(5):523-30 PMID: 4197755
  93. Persisting bacteriophage infections, lysogeny, and phage conversions.
    Annu Rev Microbiol. 1974;28(0):265-99 PMID: 4215366
  94. Pathophysiology of Shigella diarrhea in the rhesus monkey: intestinal transport, morphological, and bacteriological studies.
    Gastroenterology. 1975 Feb;68(2):270-8 PMID: 1090480
  95. Effect of Shigella enterotoxin on electrolyte transport in rabbit ileum.
    Gastroenterology. 1975 Dec;69(6):1230-7 PMID: 172398
  96. Pathogenesis of shigella diarrhea. Serum anticytotoxin antibody response produced by toxigenic and nontoxigenic Shigella dysenteriae 1.
    J Clin Invest. 1976 Jan;57(1):194-202 PMID: 1107354
  97. Inhibition of in vitro protein synthesis by Shigella dysenteriae 1 toxin.
    Biochem Biophys Res Commun. 1976 Aug 9;71(3):783-8 PMID: 786292
  98. Fluid and electrolyte transport in rhesus monkeys challenged intracecally with Shigella flexneri 2a.
    Infect Immun. 1976 Aug;14(2):368-71 PMID: 823110
  99. Diarrhea due to Escherichia coli in the rabbit: a novel mechanism.
    J Infect Dis. 1977 Mar;135(3):454-62 PMID: 321703
  100. Biological properties of Shigella flexneri 2A toxin and its serological relationship to Shigella dysenteriae 1 toxin.
    Infect Immun. 1977 Mar;15(3):796-8 PMID: 323142
  101. The pathogenesis of Shigella diarrhea. VI. Toxin and antitoxin in Shigella flexneri and Shigella sonnei infections in humans.
    J Infect Dis. 1977 Apr;135(4):552-6 PMID: 323376
Article Info
Journal
Microbiological reviews
Abbr.
Microbiol Rev
ISSN
0146-0749
DOI
10.1128/mr.51.2.206-220.1987
Published
1987-06-00
Pages
206-20
Language
English
Region
United States
NLM ID
7806086
PMCID
PMC373104
Subset
IM
Grants
NIAID NIH HHS · AI20148 · United States
External Links
PubMed source DOI: 10.1128/mr.51.2.206-220.1987 PMC Full Text
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