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PMID: 3060243 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Detection, pathogenesis, and therapy of respiratory syncytial virus infections.

Clinical microbiology reviews ·Vol. 1 ·No. 1 ·1988-01-00 ·Pages 27-39

Welliver RC

Abstract

Respiratory syncytial virus (RSV) infection is a major cause of serious lower respiratory disease in infancy and early childhood. The unique pathogenesis of lower respiratory illness due to RSV offers some intriguing clues to the role of the human immune system in both protection against and development of respiratory illness. More than any other virus, rapid diagnostic techniques have been especially successful in identifying RSV infection. Many of these techniques could be easily adaptable to diagnosis of influenza virus infection and other agents. Finally, ribavirin therapy of RSV infection represents one of the few instances in which antiviral therapy has been shown to be effective for respiratory illnesses. Fundamental observations in these areas in the case of RSV infection open up new and exciting pathways for investigation of respiratory infection due to other viral, chlamydial, and mycoplasmal agents.

MeSH Terms
Child, Preschool Humans Infant Respiratory Syncytial Viruses Respirovirus Infections/diagnosis,drug therapy,etiology
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Welliver R C
Department of Pediatrics, State University of New York at Buffalo.
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Article Info
Journal
Clinical microbiology reviews
Abbr.
Clin Microbiol Rev
ISSN
0893-8512
DOI
10.1128/CMR.1.1.27
Published
1988-01-00
Pages
27-39
Language
English
Region
United States
NLM ID
8807282
PMCID
PMC358027
Subset
IM
Grants
NIAID NIH HHS · AI-15939-01 · United States
NICHD NIH HHS · HD-15943-02 · United States
NHLBI NIH HHS · HL-21829-05 · United States
External Links
PubMed source DOI: 10.1128/CMR.1.1.27 PMC Full Text View journal details
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