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PMID: 27726481 Published · ppublish English Journal Article Review Research Support, Non-U.S. Gov't

Cajal bodies and their role in plant stress and disease responses.

RNA biology ·Vol. 14 ·No. 6 ·2017-00-03 ·Pages 779-790

Love AJ, Yu C, Petukhova NV, Kalinina NO, Chen J, Taliansky ME

Abstract

Cajal bodies (CBs) are distinct sub-nuclear structures that are present in eukaryotic living cells and are often associated with the nucleolus. CBs play important roles in RNA metabolism and formation of RNPs involved in transcription, splicing, ribosome biogenesis, and telomere maintenance. Besides these primary roles, CBs appear to be involved in additional functions that may not be directly related to RNA metabolism and RNP biogenesis. In this review, we assess possible roles of plant CBs in RNA regulatory pathways such as nonsense-mediated mRNA decay and RNA silencing. We also summarize recent progress and discuss new non-canonical functions of plant CBs in responses to stress and disease. It is hypothesized that CBs can regulate these responses via their interaction with poly(ADP ribose)polymerase (PARP), which is known to play an important role in various physiological processes including responses to biotic and abiotic stresses. It is suggested that CBs and their components modify PARP activities and functions.

Keywords
Abiotic stress Cajal bodies PARP plant viruses plants
MeSH Terms
Coiled Bodies/genetics,metabolism Gene Expression Regulation, Plant Host-Pathogen Interactions/genetics Nuclear Proteins/metabolism Plant Diseases/genetics,virology Plant Physiological Phenomena Poly(ADP-ribose) Polymerases/metabolism RNA Processing, Post-Transcriptional RNA, Small Nuclear/genetics,metabolism Ribonucleoproteins, Small Nuclear/metabolism Stress, Physiological/genetics
Chemicals
Nuclear Proteins RNA, Small Nuclear Ribonucleoproteins, Small Nuclear p80-coilin Poly(ADP-ribose) Polymerases
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Love Andrew J
a Cell and Molecular Sciences , James Hutton Institute , Invergowrie, Dundee , UK.
Yu Chulang
b State Key Laboratory Breeding Base for Sustainable Pest and Disease Control, Key Laboratory of Biotechnology in Plant Protection of MOA and Zhejiang Province , Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences , Hangzhou , China.
Petukhova Natalia V
a Cell and Molecular Sciences , James Hutton Institute , Invergowrie, Dundee , UK.
Kalinina Natalia O
c A.N. Belozersky Institute of Physico-Chemical Biology , Lomonosov Moscow State University , Leninskie Gory, Moscow , Russia.
Chen Jianping
b State Key Laboratory Breeding Base for Sustainable Pest and Disease Control, Key Laboratory of Biotechnology in Plant Protection of MOA and Zhejiang Province , Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences , Hangzhou , China.
Taliansky Michael E
a Cell and Molecular Sciences , James Hutton Institute , Invergowrie, Dundee , UK. | b State Key Laboratory Breeding Base for Sustainable Pest and Disease Control, Key Laboratory of Biotechnology in Plant Protection of MOA and Zhejiang Province , Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences , Hangzhou , China.
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Article Info
Journal
RNA biology
Abbr.
RNA Biol
ISSN
1555-8584
DOI
10.1080/15476286.2016.1243650
Published
2017-00-03
Epub
2016-00-11
Pages
779-790
Language
English
Region
United States
NLM ID
101235328
PMCID
PMC5519230
Subset
IM
External Links
PubMed source DOI: 10.1080/15476286.2016.1243650 PMC Full Text View journal details
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