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PMID: 2528940 Published · ppublish English Journal Article

Characterization of vancomycin resistance in Enterococcus faecium and Enterococcus faecalis.

Antimicrobial agents and chemotherapy ·Vol. 33 ·No. 7 ·1989-07-00 ·Pages 1121-4

Nicas TI, Wu CY, Hobbs JN, Preston DA, Allen NE

Abstract

Vancomycin resistance in Enterococcus faecium 180, a clinical isolate from England, was studied. Resistance to vancomycin was transferable by conjugation to other enterococci. Expression of resistance was inducible and coincided with the appearance of a new membrane protein.

MeSH Terms
Bacterial Outer Membrane Proteins/biosynthesis,isolation & purification Cell Wall/metabolism Drug Resistance, Microbial Electrophoresis, Polyacrylamide Gel Enterococcus faecalis/drug effects,genetics Glycopeptides/pharmacology Streptococcus/drug effects,genetics Teicoplanin Vancomycin/metabolism,pharmacology
Chemicals
Bacterial Outer Membrane Proteins Glycopeptides Teicoplanin Vancomycin
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Nicas T I
Lilly Research Laboratories, Eli Lilly & Co., Indianapolis, Indiana 46285-0438.
Wu C Y
Hobbs J N
Preston D A
Allen N E
References (9)
9 references, click to expand
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    Antimicrob Agents Chemother. 1989 Jan;33(1):10-5 PMID: 2523687
  9. Inducible, transferable resistance to vancomycin in Enterococcus faecalis A256.
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.33.7.1121
Published
1989-07-00
Pages
1121-4
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC176076
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.33.7.1121 PMC Full Text View journal details
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