Adenovirus and minute virus of mice DNAs are localized at the nuclear periphery.
The localization of adenovirus 2 (Ad2) and Minute Virus of Mice (MVM) DNAs was studied in situ in infected HeLa cell nuclei using fluorescent DNA probes and confocal microscopy. Ad2 DNA was found in multiple foci which were localized along the periphery of the infected cell nuclei. MVM DNA was found in HeLa cell nucleoli which are associated with the nuclear envelope, and when co-infected with Ad2 MVM DNA was compartmentalized to multiple foci which again were localized at the nuclear periphery. The data are discussed in terms of a model for the role of intranuclear compartmentalization in eukaryotic DNA structure and function.
21 references, click to expand
-
Sensitive, high-resolution chromatin and chromosome mapping in situ: presence and orientation of two closely integrated copies of EBV in a lymphoma line.Cell. 1988 Jan 15;52(1):51-61 PMID: 2830981
-
Confocal microscopy: an overview.Biotechniques. 1989 Feb;7(2):154-63 PMID: 2517017
-
Isolation of DNA replication complexes from uninfected and adenovirus-infected HeLa cells.J Mol Biol. 1971 Nov 28;62(1):65-80 PMID: 5157354
-
Macromolecular content of inclusions produced by a canine adenovirus.J Virol. 1972 Oct;10(4):801-9 PMID: 4673491
-
The viral DNA replication complex of adenovirus 12.Virology. 1974 Jul;60(1):192-9 PMID: 4841176
-
Intranuclear site of replication of adenovirus DNA.J Mol Biol. 1974 Nov 5;89(3):423-33 PMID: 4444054
-
Localization of adenovirus DNA replication in KB cells.Virology. 1975 Jun;65(2):535-45 PMID: 1129949
-
Kinetics of adenovirus DNA replication II. Initiation of adenovirus DNA replication.Virology. 1980 Sep;105(2):357-70 PMID: 7423853
-
Sequential association of nucleolar 7-2 RNA with two different autoantigens.J Biol Chem. 1983 Feb 10;258(3):1379-82 PMID: 6185483
-
Three-dimensional architecture of a polytene nucleus.Nature. 1983 Apr 21;302(5910):676-81 PMID: 6403872
-
Construction of an infectious molecular clone of the autonomous parvovirus minute virus of mice.J Virol. 1983 Jul;47(1):227-32 PMID: 6345805
-
Localization of DNAase I-sensitive sequences to specific regions of interphase nuclei.Cell. 1985 Dec;43(2 Pt 1):471-82 PMID: 4075401
-
Identification of two nuclear subclasses of the adenovirus type 5-encoded DNA-binding protein.J Virol. 1986 Nov;60(2):353-62 PMID: 2945931
-
Alterations in nuclear matrix structure after adenovirus infection.J Virol. 1987 Apr;61(4):1007-18 PMID: 3820360
-
Three-dimensional organization of Drosophila melanogaster interphase nuclei. II. Chromosome spatial organization and gene regulation.J Cell Biol. 1987 Jun;104(6):1471-83 PMID: 3108265
-
A domain model for eukaryotic DNA organization: a molecular basis for cell differentiation and chromosome evolution.J Theor Biol. 1988 Jun 22;132(4):479-507 PMID: 3226138
-
Spatial relationship between the nucleolus and the nuclear envelope: structural aspects and functional significance.Int Rev Cytol. 1988;111:1-52 PMID: 3074957
-
Interactions of minute virus of mice and adenovirus with host nucleoli.J Virol. 1989 Sep;63(9):3651-60 PMID: 2760977
-
The terminal regions of adenovirus and minute virus of mice DNAs are preferentially associated with the nuclear matrix in infected cells.J Virol. 1989 Oct;63(10):4344-53 PMID: 2778878
-
The domain model for eukaryotic DNA organization. 2: A molecular basis for constraints on development and evolution.J Theor Biol. 1989 Apr 6;137(3):281-320 PMID: 2601348
-
Mapping replicational sites in the eucaryotic cell nucleus.J Cell Biol. 1989 Jan;108(1):1-11 PMID: 2910875
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