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PMID: 22417 Published · ppublish English Journal Article

Drug kinetics and artificial kidneys.

Clinical pharmacokinetics ·Vol. 2 ·No. 6 ·1977-00-00 ·Pages 403-26

Gibson TB, Nelson HA

Abstract

The factors affecting solute movement across the membrane during haemodialysis are well understood. Likewise the mathematics of drug kinetics are well described. However, studies of the effects of artificial kidneys on drug kinetics have often been limited by a lack of attention to proper methods of calculating solute clearance by the artificial kidney.

MeSH Terms
Analgesics/metabolism Anti-Anxiety Agents/metabolism Anti-Arrhythmia Agents/metabolism Anti-Bacterial Agents/metabolism Cardiac Glycosides/metabolism Half-Life Humans Hypnotics and Sedatives/metabolism Kidneys, Artificial Pharmaceutical Preparations/metabolism Protein Binding Renal Dialysis
Chemicals
Analgesics Anti-Anxiety Agents Anti-Arrhythmia Agents Anti-Bacterial Agents Cardiac Glycosides Hypnotics and Sedatives Pharmaceutical Preparations
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Gibson T B
Nelson H A
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Article Info
Journal
Clinical pharmacokinetics
Abbr.
Clin Pharmacokinet
ISSN
0312-5963
DOI
10.2165/00003088-197702060-00002
Published
1977-00-00
Pages
403-26
Language
English
Region
Switzerland
NLM ID
7606849
Subset
IM
External Links
PubMed source DOI: 10.2165/00003088-197702060-00002 View journal details
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