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PMID: 1889807 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Chromosomal mapping of brain-derived neurotrophic factor and neurotrophin-3 genes in man and mouse.

Genomics ·Vol. 10 ·No. 3 ·1991-07-00 ·Pages 569-75

Ozçelik T, Rosenthal A, Francke U

Abstract

Brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NTF3) are two new members of the nerve growth factor gene family, which play important roles in the development and maintenance of the vertebrate nervous system. Here we describe the assignments of the BDNF and NTF3 gene loci to human and mouse chromosomes and discuss the evolutionary relationship of human chromosomes 11 and 12. BDNF has been mapped to human chromosome 11p15.5-p11.2 and to mouse chromosome 2, and NTF3 to human chromosome 12p and mouse chromosome 6.

Related Genes
BDNF Bdnf HRAS1 IGF1 IGF2 INS KRAS2 LDHA LDHB NGFB NRAS NRASL NTF3 Ntf-3 PAH PTH PTHLH RLN1 RLN2 TH ras
MeSH Terms
Animals Brain-Derived Neurotrophic Factor Chromosome Mapping Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 12 Cricetinae Cricetulus Genetic Markers Hormones/genetics Humans Hybrid Cells Mice/genetics Multigene Family Nerve Growth Factors/genetics Nerve Tissue Proteins/genetics Neurotrophin 3 Oncogenes Phylogeny Rats Species Specificity
Chemicals
Brain-Derived Neurotrophic Factor Genetic Markers Hormones Nerve Growth Factors Nerve Tissue Proteins Neurotrophin 3
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Ozçelik T
Howard Hughes Medical Institute, Stanford University Medical Center, California 94305.
Rosenthal A
Francke U
Article Info
Journal
Genomics
Abbr.
Genomics
ISSN
0888-7543
DOI
10.1016/0888-7543(91)90437-j
Published
1991-07-00
Pages
569-75
Language
English
Region
United States
NLM ID
8800135
Subset
IM
Grants
NHGRI NIH HHS · HG00298 · United States
External Links
PubMed source DOI: 10.1016/0888-7543(91)90437-j View journal details
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