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PMID: 17823244 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Silencing of poly(ADP-ribose) polymerase in plants alters abiotic stress signal transduction.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 104 ·No. 38 ·2007-09-18 ·Pages 15150-5

Vanderauwera S, De Block M, Van de Steene N, van de Cotte B, Metzlaff M, Van Breusegem F

Abstract

Transgenic plants with reduced poly(ADP-ribose) polymerase (PARP) levels have broad-spectrum stress-resistant phenotypes. Both Arabidopsis thaliana and oilseed rape (Brassica napus) lines overexpressing RNA interference-PARP constructs were more resistant to various abiotic stress treatments in laboratory and greenhouse experiments without negative effects on growth, development, and seed production. This outperforming stress tolerance was initially attributed solely to a maintained energy homeostasis due to reduced NAD(+) consumption. We show that in PARP2-deficient Arabidopsis plants, the observed abiotic stress resistance can also be explained by alterations in abscisic acid levels that facilitate the induction of a wide set of defense-related genes.

MeSH Terms
Arabidopsis/enzymology,genetics,metabolism Arabidopsis Proteins/genetics,metabolism Cyclic ADP-Ribose/metabolism Gene Expression Regulation, Plant Genome, Plant Microarray Analysis Models, Biological Oxidative Stress Poly(ADP-ribose) Polymerases/genetics,metabolism RNA Interference Signal Transduction/genetics Transcription, Genetic
Chemicals
Arabidopsis Proteins Cyclic ADP-Ribose Poly(ADP-ribose) Polymerases
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Vanderauwera Sandy
Department of Plant Systems Biology, Flanders Institute for Biotechnology (VIB), Technologiepark 927, 9052 Ghent, Belgium.
De Block Marc
Van de Steene Nancy
van de Cotte Brigitte
Metzlaff Michael
Van Breusegem Frank
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.0706668104
Published
2007-09-18
Epub
2007-00-06
Pages
15150-5
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC1986628
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.0706668104 PMC Full Text View journal details
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