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PMID: 9405349 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Abscisic acid signaling through cyclic ADP-ribose in plants.

Science (New York, N.Y.) ·Vol. 278 ·No. 5346 ·1997-12-19 ·Pages 2126-30

Wu Y, Kuzma J, Maréchal E, Graeff R, Lee HC, Foster R, Chua NH

Abstract

Abscisic acid (ABA) is the primary hormone that mediates plant responses to stresses such as cold, drought, and salinity. Single-cell microinjection experiments in tomato were used to identify possible intermediates involved in ABA signal transduction. Cyclic ADP-ribose (cADPR) was identified as a signaling molecule in the ABA response and was shown to exert its effects by way of calcium. Bioassay experiments showed that the amounts of cADPR in Arabidopsis thaliana plants increased in response to ABA treatment and before ABA-induced gene expression.

MeSH Terms

Abscisic Acid/pharmacology Adenosine Diphosphate Ribose/analogs & derivatives,metabolism,pharmacology Arabidopsis/genetics,metabolism Arabidopsis Proteins Calcium/metabolism,pharmacology Cyclic ADP-Ribose Egtazic Acid/pharmacology GTP-Binding Proteins/physiology Gene Expression Regulation, Plant/drug effects Genes, Reporter Inositol Phosphates/pharmacology Lycopersicon esculentum/genetics,metabolism Microinjections Phosphoprotein Phosphatases/metabolism Phosphorylation Phytochrome/pharmacology Phytochrome A Plants/genetics,metabolism Plants, Genetically Modified Protein Kinases/metabolism Second Messenger Systems Signal Transduction

Chemicals

Arabidopsis Proteins Inositol Phosphates PHYA protein, Arabidopsis Phytochrome A Phytochrome Cyclic ADP-Ribose Adenosine Diphosphate Ribose Egtazic Acid Abscisic Acid Protein Kinases Phosphoprotein Phosphatases GTP-Binding Proteins Calcium

Authors & Affiliations

7 authors, click to expand affiliations / ORCID

Wu Y

Laboratory of Plant Molecular Biology, Rockefeller University, 1230 York Avenue, New York, NY 10021-6399, USA.

Kuzma J

Maréchal E

Graeff R

Lee H C

Foster R

Chua N H

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.278.5346.2126

Published

1997-12-19

Pages

2126-30

Language

English

Region

United States

NLM ID

0404511

Subset

Grants

NICHD NIH HHS · HD17484 · United States

Corrections

CommentIn

PMID: 9432717

External Links

PubMed source DOI: 10.1126/science.278.5346.2126 View journal details

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Abscisic acid signaling through cyclic ADP-ribose in plants.

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