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PMID: 16821138 Published · ppublish English Journal Article Review

ATP-dependent chromatin remodeling complexes in Drosophila.

Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology ·Vol. 14 ·No. 4 ·2006-00-00 ·Pages 433-49

Bouazoune K, Brehm A

Abstract

The regulation of chromatin structure is of fundamental importance for many DNA-based processes in eukaryotes. Activation or repression of gene transcription or DNA replication depends on enzymes which can generate the appropriate chromatin environment. Several of these enzymes utilize the energy of ATP hydrolysis to alter nucleosome structure. In recent years our understanding of the multisubunit complexes within which they function, their mechanisms of action, their regulation and their in-vivo roles has increased. Much of what we have learned has been gleaned from studies in Drosophila melanogaster. Here we will review what we know about the main classes of ATP-dependent chromatin remodelers in Drosophila.

MeSH Terms
Adenosine Triphosphatases/genetics,physiology Animals Autoantigens Chromatin Assembly and Disassembly/genetics,physiology DNA Helicases DNA-Binding Proteins/genetics Drosophila/genetics Drosophila Proteins/genetics Dyneins Homeodomain Proteins Transcription Factors/genetics
Chemicals
Autoantigens CHD1 protein, Drosophila DNA-Binding Proteins Drosophila Proteins Homeodomain Proteins ISWI protein Mi-2 protein, Drosophila Transcription Factors sw protein, Drosophila Adenosine Triphosphatases DNA Helicases Dyneins kis protein, Drosophila
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Bouazoune Karim
Massachusetts General Hospital, Department of Molecular Biology, Harvard Medical School, Department of Genetics, 185 Cambridge Street, Boston, MA 02114, USA.
Brehm Alexander
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Article Info
Journal
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology
Abbr.
Chromosome Res
ISSN
0967-3849
DOI
10.1007/s10577-006-1067-0
Published
2006-00-00
Pages
433-49
Language
English
Region
Netherlands
NLM ID
9313452
Subset
IM
External Links
PubMed source DOI: 10.1007/s10577-006-1067-0 View journal details
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