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PMID: 15709039 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Severe acute respiratory syndrome coronavirus 3a protein is a viral structural protein.

Journal of virology ·Vol. 79 ·No. 5 ·2005-03-00 ·Pages 3182-6

Ito N, Mossel EC, Narayanan K, Popov VL, Huang C, Inoue T, Peters CJ, Makino S

Abstract

The present study showed the association of a severe acute respiratory syndrome coronavirus (SCoV) accessory protein, 3a, with plasma membrane and intracellular SCoV particles in infected cells. 3a protein appeared to undergo posttranslational modifications in infected cells and was incorporated into SCoV particles, establishing that 3a protein was a SCoV structural protein.

MeSH Terms
Animals Caco-2 Cells Chlorocebus aethiops Humans Microscopy, Immunoelectron Protein Processing, Post-Translational SARS Virus/genetics,physiology,ultrastructure Vero Cells Viral Envelope Proteins Viral Proteins/genetics,isolation & purification,physiology Viral Structural Proteins/genetics,isolation & purification,physiology Viroporin Proteins
Chemicals
3a protein, SARS-CoV Viral Envelope Proteins Viral Proteins Viral Structural Proteins Viroporin Proteins
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Ito Naoto
Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-1019, USA.
Mossel Eric C
Narayanan Krishna
Popov Vsevolod L
Huang Cheng
Inoue Taisuke
Peters Clarence J
Makino Shinji
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.79.5.3182-3186.2005
Published
2005-03-00
Pages
3182-6
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC548460
Subset
IM
Grants
NIAID NIH HHS · T32 AI007536 · United States
NIAID NIH HHS · N01AI25489 · United States
NIAID NIH HHS · AI007536 · United States
NIAID NIH HHS · AI29984 · United States
NIAID NIH HHS · R21 AI029984 · United States
NIAID NIH HHS · R01 AI029984 · United States
External Links
PubMed source DOI: 10.1128/JVI.79.5.3182-3186.2005 PMC Full Text View journal details
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