A study of the properties of the free amino acid pool and enzyme synthesis in yeast.

The Journal of general physiology ·Vol. 38 ·No. 4 ·1955-03-20 ·Pages 549-73

HALVORSON H, FRY W, SCHWEMMIN D

Abstract

A study has been made of the distribution and properties of the free amino acid pool in yeast. The depletion of the pool was found to depend upon the energy source used, conditions of growth, and the nature of the exogenous nitrogen source. Pool levels could be restored either by an internal replenishment mechanism or by various nitrogen sources. In the absence of internal replenishment a strong positive correlation was established between the ability of nitrogen compounds to support free glutamic add synthesis and enzyme-synthesizing capacity. Amino acid assimilation by nitrogen-starved yeast was studied and compared with that in other organisms. The significance of these results for the problem of enzyme and protein synthesis in yeast is discussed.

Keywords

AMINO ACIDS/metabolism ENZYMES YEASTS/metabolism

MeSH Terms

Amino Acids/metabolism Enzymes Nitrogen Saccharomyces cerevisiae Yeasts/metabolism

Chemicals

Amino Acids Enzymes Nitrogen

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

HALVORSON H

FRY W

SCHWEMMIN D

References (14)

14 references, click to expand

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Article Info

Journal

The Journal of general physiology

Abbr.

J Gen Physiol

ISSN

0022-1295

DOI

10.1085/jgp.38.4.549

Published

1955-03-20

Pages

549-73

Language

English

Region

United States

NLM ID

2985110R

PMCID

PMC2147491

Subset

External Links

PubMed source DOI: 10.1085/jgp.38.4.549 PMC Full Text View journal details

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A study of the properties of the free amino acid pool and enzyme synthesis in yeast.

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