Uric acid production in gout.

The Journal of clinical investigation ·Vol. 40 ·1961-07-00 ·Pages 1304-14

SEEGMILLER JE, GRAYZEL AI, LASTER L, LIDDLE L

Abstract

暂无摘要

Keywords

GOUT/metabolism URIC ACID/metabolism

MeSH Terms

Aged Gout/metabolism Humans Uric Acid/metabolism

Chemicals

Uric Acid

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

SEEGMILLER J E

GRAYZEL A I

LASTER L

LIDDLE L

References (24)

24 references, click to expand

Acute gouty arthritis precipitated by chlorothiazide.
N Engl J Med. 1960 Apr 14;262:767-9 PMID: 13794462
Uricolysis in normal and gouty individuals.
Ann Rheum Dis. 1955 Dec;14(4):409-11 PMID: 13275882
Effect of sodium lactate infusion on urate clearance in man.
Proc Soc Exp Biol Med. 1957 Dec;96(3):809-13 PMID: 13505867
Normal glycine-C14-incorporation into uric acid in primary gout.
Metabolism. 1958 Jul;7(4 Pt 1):374-5 PMID: 13565391
Failure to detect consistent overincorporation of glycine-1-C14 into uric acid in primary gout.
Metabolism. 1958 Jul;7(4 Pt 1):376-7 PMID: 13565392
The enzymatic spectrophotometric method for determination of uric acid.
J Lab Clin Med. 1959 Dec;54:903-13 PMID: 14416793
Incorporation of glycine nitrogen into uric acid in normal and gouty man.
Metabolism. 1952 Jan;1(1):3-12 PMID: 14890550
Uric acid retention due to hydrochlorothiazide.
N Engl J Med. 1959 Dec 31;261:1358-62 PMID: 14400417
Renal function in gout; with a commentary on the renal regulation of urate excretion, and the role of the kidney in the pathogenesis of gout.
Am J Med. 1957 Oct;23(4):600-22 PMID: 13469831
The role of lactic acid in the reduced excretion of uric acid in toxemia of pregnancy.
J Clin Invest. 1960 Oct;39:1526-32 PMID: 13711188
The renal excretion of uric acid in patients with gout and in nongouty subjects.
J Clin Invest. 1959 Nov;38:1890-8 PMID: 14427889
Chlorothiazide (diuril) as a hyperuricaci'emic agent.
J Am Med Assoc. 1958 Dec 20;168(16):2128-9 PMID: 13598659
Overproduction of uric acid as the cause of hyperuricemia in primary gout.
J Clin Invest. 1957 Oct;36(10):1508-15 PMID: 13475488
The effect of salicylates and adrenocorticotropic hormone upon the miscible pool of uric acid in gout.
J Clin Invest. 1950 Aug;29(8):1104-11 PMID: 15436881
Hyperuricemia due to pyrazinamide.
Am J Med. 1957 Oct;23(4):596-9 PMID: 13469830
The metabolism of uric acid in the normal and gouty human studied with the aid of isotopic uric acid.
J Biol Chem. 1949 Nov;181(1):183-93 PMID: 15390405
Incorporation of glycine-1-C14, glycine-2-C14 and glycine-N15 into uric acid in normal and gouty subjects.
Am J Med. 1958 Dec;25(6):917-32 PMID: 13606143
Studies of hyperuricemia produced by pyrazinamide.
Am J Med. 1957 Oct;23(4):587-95 PMID: 13469829
Pool size, turnover rate, and rapidity of equilibration of injected isotopic uric acid in normal and pathological subjects.
J Clin Invest. 1951 Aug;30(8):879-88 PMID: 14861310
The origin of urinary creatine in progressive muscular dystrophy.
J Clin Invest. 1955 Jan;34(1):141-5 PMID: 13221666
The first glycine metabolic pool in man.
Biochem J. 1959 Oct;73:277-86 PMID: 13843179
Degradation of uric acid in man.
Metabolism. 1959 Sep;8:687-703 PMID: 13832881
Suppression of uric acid synthesis in the gouty human by the use of 6-diazo-5-oxo-L-norleucine.
J Clin Invest. 1960 Mar;39:447-54 PMID: 13829149
A further study of the utilization of dietary glycine nitrogen for uric acid synthesis in gout.
J Clin Invest. 1953 Aug;32(8):775-7 PMID: 13069625

Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

10.1172/JCI104360

Published

1961-07-00

Pages

1304-14

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC290843

Subset

External Links

PubMed source DOI: 10.1172/JCI104360 PMC Full Text View journal details

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