Overproduction of uric acid as the cause of hyperuricemia in primary gout.

The Journal of clinical investigation ·Vol. 36 ·No. 10 ·1957-10-00 ·Pages 1508-15

WYNGAARDEN JB

Abstract

暂无摘要

Keywords

GOUT/blood in URIC ACID/in blood

MeSH Terms

Gout/blood Humans Hyperuricemia Uric Acid/blood

Chemicals

Uric Acid

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

WYNGAARDEN J B

References (17)

17 references, click to expand

Rate of conversion of isotopic glycine to uric acid in the normal and gouty human and how this is affected by vitamin E and folic acid.
Metabolism. 1955 Mar;4(2):174-82 PMID: 14355635
Intermediary purine metabolism and the metabolic defects of gout.
Metabolism. 1957 May;6(3):244-68 PMID: 13430358
Uricolysis in normal and gouty individuals.
Ann Rheum Dis. 1955 Dec;14(4):409-11 PMID: 13275882
The biosynthesis of nucleic acid components studied with C14. I. Purines and pyrimidines in the rat.
J Biol Chem. 1950 Oct;186(2):447-60 PMID: 14794640
The fate of uric acid in the normal and gouty human being.
J Chronic Dis. 1955 Jul;2(1):42-9 PMID: 14392181
Incorporation of glycine nitrogen into uric acid in normal and gouty man.
Metabolism. 1952 Jan;1(1):3-12 PMID: 14890550
Increased renal excretion of urate in young patients with gout.
Am J Med. 1950 Jul;9(1):31-4 PMID: 15425531
Uric acid production in normal and gouty subjects, determined by N15 labeled glycine.
Proc Soc Exp Biol Med. 1953 Jan;82(1):47-50 PMID: 13037798
Incorporation of 4-amino-5-imidazolecarboxamide-4-C13 into uric acid in the normal human.
J Biol Chem. 1955 Oct;216(2):653-62 PMID: 13271342
Uricolysis in normal man.
J Biol Chem. 1953 Jul;203(1):9-21 PMID: 13069482
Recent contributions to the understanding of the metabolic defect in gout.
Geriatrics. 1954 Apr;9(4):163-71 PMID: 13151400
Effect of phenylbutazone (3,5 dioxo-1,2-diphenyl-4-n-butylpyrazolidine) on renal clearance of urate and other discrete renal functions in gouty subjects.
J Clin Invest. 1953 Nov;32(11):1121-32 PMID: 13108975
Windowless, Flow Type, Proportional Counter for Counting C14.
Science. 1950 Aug 18;112(2903):198-9 PMID: 17759216
Physiological disposition and metabolic fate of infused pentoses in man.
J Clin Invest. 1957 Oct;36(10):1395-407 PMID: 13475480
The origin of urinary creatine in progressive muscular dystrophy.
J Clin Invest. 1955 Jan;34(1):141-5 PMID: 13221666
A further study of the utilization of dietary glycine nitrogen for uric acid synthesis in gout.
J Clin Invest. 1953 Aug;32(8):775-7 PMID: 13069625
Effect of benemid (p-[di-n-propylsulfamyl]-benzoic acid) on urate clearance and other discrete renal functions in gouty subjects.
J Clin Invest. 1952 Jul;31(7):692-701 PMID: 14938444

Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

10.1172/JCI103547

Published

1957-10-00

Pages

1508-15

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC1072750

Subset

External Links

PubMed source DOI: 10.1172/JCI103547 PMC Full Text View journal details

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Overproduction of uric acid as the cause of hyperuricemia in primary gout.

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