Transfer RNA methylating activity of yeast mitochondria.

Nucleic acids research ·Vol. 1 ·No. 5 ·1974-05-00 ·Pages 707-18

Smolar N, Svensson I

Abstract

Mitochondria isolated from Saccharomyces cerevisiae and purified in Urografin or sucrose gradient contain tRNA methylating activity with specificities different from those of the cytoplasm. The main reaction product, using E.coli tRNA as methyl group acceptor, is N(2),-N(2)-dimethylguanine. The corresponding mitochondrial methylase is coded by nuclear DNA. A DNA methylating activity is also associated with yeast mitochondria.

MeSH Terms

Escherichia coli/metabolism Methylation Mitochondria/metabolism RNA, Bacterial/chemistry,metabolism RNA, Transfer/chemistry,metabolism Saccharomyces cerevisiae/metabolism tRNA Methyltransferases/metabolism

Chemicals

RNA, Bacterial RNA, Transfer tRNA Methyltransferases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Smolar N

Svensson I

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29 references, click to expand

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Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/1.5.707

Published

1974-05-00

Pages

707-18

Language

English

Region

England

NLM ID

0411011

PMCID

PMC343371

Subset

External Links

PubMed source DOI: 10.1093/nar/1.5.707 PMC Full Text View journal details

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Transfer RNA methylating activity of yeast mitochondria.

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