ID2(inhibitor of DNA binding 2, dominant negative helix-loop-helix protein)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

2p25
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Aug 2011]

[中文简述(自动翻译):]  由该基因编码的蛋白质属于DNA结合家族的抑制剂，其成员是含有螺旋 - 环 - 螺旋（HLH）结构域，但不是基本域的转录调节。 DNA结合家族的抑制剂的成员通过该HLH结构域抑制其异源伙伴抑制显性负方式的碱性螺旋 - 环 - 螺旋转录因子的功能。这种蛋白质可以在细胞分化负调节中发挥作用。该基因的假基因位于[由RefSeq的，2011年8月提供] 3号染色体

OMIM数据库中对ID2基因的介绍     Wikipedia数据库中对ID2基因的介绍

基因序列

基因序列

ID2基因的碱基序列：[NCBI]

基因突变

基因突变

ID2基因的碱基突变：           显示全部snp
rs4899       rs1317966       rs2241740       rs2306067       rs3845751       rs5829178       rs7601195       rs11885600       rs11904319       rs35434759       rs55940816       rs56043919       rs56393729       rs73147096       rs74467097       rs74915181       rs75679432       rs75776490       rs76714575       rs78686863       rs80204205       rs80280742       rs80299736       rs112175658       rs113690930       rs114406044       rs115236910       rs115399969       rs115899430       rs116448613       rs138245120       rs138757092       rs139842287       rs140172462       rs141179746       rs141878294       rs141896686      
rs143160183       rs146297199       rs147849051       rs148245442       rs149826728       rs150794270       rs180870732       rs181038180       rs182538570       rs182750881       rs183093556       rs184340832       rs185715943       rs185992340       rs186122483       rs187229888       rs187448341       rs188226977       rs188919269       rs190266143       rs190628922       rs192218502       rs192378104       rs192510893       rs193263132       rs200036190       rs200323055       rs200461867       rs200785774       rs200831448       rs200965294       rs201247626       rs201480328       rs201970478       rs367687820       rs367911935       rs368166936       rs368596105       rs369294315       rs369687542       rs369813445       rs370268374       rs370283962       rs370458191       rs371033023       rs371697958       rs371946564       rs372117829       rs372237811       rs372282921       rs372837543       rs373045012       rs374730683       rs374854911       rs374872738       rs375848588       rs376253439       rs376944573       rs377037800       rs377120348       rs527701869       rs529664038       rs530261721       rs531425698       rs531625791       rs532057872       rs532260886       rs533546964       rs533632040       rs533721579       rs534072714       rs534587167       rs534681364       rs535835971       rs536056805       rs536091820       rs536697369       rs537189047       rs537665525       rs538235908       rs540109576       rs541003847       rs542193801       rs543900939       rs544317017       rs544784178       rs545058542       rs545689941       rs546770517       rs547319053       rs549415071       rs549981465       rs551480481       rs551788901       rs552438486       rs552524818       rs553391485       rs553577196       rs553667391       rs554635392       rs554723196       rs555458251       rs555914439       rs557000216       rs558226738       rs558838352       rs559672942       rs560621744       rs560711015       rs562390361       rs562872744       rs563026346       rs563111101       rs563224799       rs564653539       rs564842198       rs564886395       rs564978708       rs565648612       rs565729838       rs566531901       rs566842473       rs567093271       rs567150767       rs568055526       rs568157668       rs568167261       rs568288457       rs569167238       rs569849908       rs570115222       rs570994879       rs571102487       rs571387001       rs571627491       rs572073643       rs572163800       rs572438956       rs573595178       rs573631972       rs575947759       rs745525450       rs745768418       rs746017528       rs746070871       rs746301579       rs746645156       rs746664433       rs747726530       rs747779416       rs748588572       rs748895574       rs749259495       rs750035083       rs750130383       rs750362423       rs750890570       rs751058126       rs751241949       rs751306378       rs751441855       rs751738585       rs751759340       rs752754481       rs752952953       rs753568797       rs754358325       rs754529022       rs754819869       rs755050813       rs755296887       rs755701807       rs756254644       rs756541338       rs756708598       rs756868058       rs757610838       rs757670099       rs757859222       rs757979957       rs758169687       rs758625876       rs759165008       rs760158586       rs760941061       rs761246768       rs762013661       rs762271194       rs762322038       rs762681427       rs762712584       rs762964659       rs763287365       rs763639723       rs763895722       rs763950440       rs764573974       rs765009908       rs765559115       rs765612480       rs766065053       rs766304565       rs766410241       rs766579151       rs767153720       rs767257397       rs767508092       rs767916717       rs768085335       rs768297218       rs768347512       rs769283815       rs770040631       rs770220563       rs770825384       rs770880239       rs771070065       rs771398773       rs771885289       rs772540768       rs773067195       rs773532008       rs773706127       rs774186526       rs774238348       rs774361814       rs774715896       rs774801755       rs775057112       rs775200073       rs775949491       rs776548502       rs776715559       rs777047997       rs777266112       rs777618124       rs777955692       rs778724135       rs778774994       rs778852406       rs778965603       rs779048693       rs779166336       rs779522291       rs779547144       rs779958591       rs780196555       rs781291332       rs781702080       rs781778827       rs866303373       rs3900795       rs6724553       rs10182838       rs11894184       rs11898041       rs74465522       rs75753391       rs77092518       rs112176563       rs140487184       rs142541551       rs147763639       rs181781527       rs184300151       rs184949920       rs186143022       rs189558000       rs189748725       rs192055392       rs373341223       rs530542858       rs532817999       rs536414227       rs537434836       rs539192057       rs541335646       rs543520892       rs546327466       rs548504171       rs555260556       rs557124966       rs561027520       rs561735228       rs562001182       rs563781764       rs563964728       rs574798390       rs577296674       rs577807398      

基因表达

基因表达

ID2基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TATTGTCAGCCTGCATCAC
58
AATTCAGAAGCCTGCAAGG
58
CTTTCCAGGCTTCTGAATTCC
59
TCATGAACACCGCTTATTCAG
59
CTATTGTCAGCCTGCATCAC
59
ATTCAGAAGCCTGCAAGGA
59
CTATTGTCAGCCTGCATCAC
59
AATTCAGAAGCCTGCAAGG
58
GGCTTCTGAATTCCCTTCTG
59
AAGAAATCATGAACACCGCT
58
TATTGTCAGCCTGCATCAC
58
AATTCAGAAGCCTGCAAGG
58
CTATTGTCAGCCTGCATCAC
59
AATTCAGAAGCCTGCAAGG
58
TTTCCAGGCTTCTGAATTCC
58
TCATGAACACCGCTTATTCAG
59
CTATTGTCAGCCTGCATCAC
59
AATTCAGAAGCCTGCAAGG
58
CTATTGTCAGCCTGCATCAC
59
ATTCAGAAGCCTGCAAGGA
59

转录因子

转录因子

转录因子
影响类型
PubMed链接
SNAI1
Activation
22551584
TERT
Unknown
14611815

基因本体信息

ID2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ID2基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000122
Q02363(UniProtKB)
IEA
GO:0001656
Q02363(UniProtKB)
IEA
GO:0001779
Q02363(UniProtKB)
IEA
GO:0001966
Q02363(UniProtKB)
IEA
GO:0003149
Q02363(UniProtKB)
IEA
GO:0003166
Q02363(UniProtKB)
IEA
GO:0005515
Q02363(UniProtKB)
IPI
GO:0005515
Q02363(UniProtKB)
IPI
GO:0005515
Q02363(UniProtKB)
IPI
GO:0005515
Q02363(UniProtKB)
IPI
GO:0005515
Q02363(UniProtKB)
IPI
GO:0005515
Q02363(UniProtKB)
IPI
GO:0005515
Q02363(UniProtKB)
IPI
GO:0005634
Q02363(UniProtKB)
IDA
GO:0005654
Q02363(UniProtKB)
IDA
GO:0005737
Q02363(UniProtKB)
IDA
GO:0005737
Q02363(UniProtKB)
IDA
GO:0005813
Q02363(UniProtKB)
IDA
GO:0005829
Q02363(UniProtKB)
IDA
GO:0006351
Q02363(UniProtKB)
IEA
GO:0007275
Q02363(UniProtKB)
TAS
GO:0008344
Q02363(UniProtKB)
IEA
GO:0010628
Q02363(UniProtKB)
ISS
GO:0010629
Q02363(UniProtKB)
ISS
GO:0014003
Q02363(UniProtKB)
IEA
GO:0019216
Q02363(UniProtKB)
ISS
GO:0021772
Q02363(UniProtKB)
IEA
GO:0032922
Q02363(UniProtKB)
ISS
GO:0033598
Q02363(UniProtKB)
ISS
GO:0042752
Q02363(UniProtKB)
ISS
GO:0043153
Q02363(UniProtKB)
ISS
GO:0043234
Q02363(UniProtKB)
ISS
GO:0043353
Q02363(UniProtKB)
IEA
GO:0043392
Q02363(UniProtKB)
IEA
GO:0043433
Q02363(UniProtKB)
IDA
GO:0044325
Q02363(UniProtKB)
IPI
GO:0045475
Q02363(UniProtKB)
ISS
GO:0045578
Q02363(UniProtKB)
IEA
GO:0045600
Q02363(UniProtKB)
IEA
GO:0045648
Q02363(UniProtKB)
IEA
GO:0045651
Q02363(UniProtKB)
IEA
GO:0045665
Q02363(UniProtKB)
ISS
GO:0045668
Q02363(UniProtKB)
IEA
GO:0045777
Q02363(UniProtKB)
ISS
GO:0045892
Q02363(UniProtKB)
IDA
GO:0045893
Q02363(UniProtKB)
ISS
GO:0046983
Q02363(UniProtKB)
IEA
GO:0048469
Q02363(UniProtKB)
IEA
GO:0048541
Q02363(UniProtKB)
IEA
GO:0048557
Q02363(UniProtKB)
ISS
GO:0048661
Q02363(UniProtKB)
ISS
GO:0048663
Q02363(UniProtKB)
ISS
GO:0048667
Q02363(UniProtKB)
IEA
GO:0048711
Q02363(UniProtKB)
IEA
GO:0048715
Q02363(UniProtKB)
IEA
GO:0060612
Q02363(UniProtKB)
IEA
GO:0060749
Q02363(UniProtKB)
ISS
GO:0061030
Q02363(UniProtKB)
ISS
GO:0061031
Q02363(UniProtKB)
ISS
GO:0071158
Q02363(UniProtKB)
ISS
GO:0071285
Q02363(UniProtKB)
IEA
GO:0071931
Q02363(UniProtKB)
IC
GO:0090398
Q02363(UniProtKB)
ISS
GO:2000045
Q02363(UniProtKB)
IMP
GO:2000178
Q02363(UniProtKB)
ISS
GO:0005737
Q02363(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控ID2基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Leukemia, Myelocytic, Acute 0.12 1 0 CTD_human
Liver Cirrhosis, Experimental 0.12 1 0 CTD_human
Dermatologic disorders 0.12 1 0 CTD_human
Thyroid Diseases 0.12 1 0 CTD_human
Small cell carcinoma of lung 0.12 1 0 CTD_human
Arsenic Poisoning 0.12 1 0 CTD_human
Neuroblastoma 0.006263026 4 0 BeFree_LHGDN
Hodgkin Disease 0.0054487 2 0 LHGDN
Hypertensive disease 0.002995792 2 0 BeFree_LHGDN
T-Cell Lymphoma 0.002995792 1 0 BeFree_LHGDN
Malignant neoplasm of ovary 0.002909916 3 0 BeFree_GAD
Squamous cell carcinoma 0.00272435 1 0 LHGDN
Acute Promyelocytic Leukemia 0.00272435 1 0 LHGDN
Lung Neoplasms 0.00272435 1 0 LHGDN
Prostatic Neoplasms 0.00272435 1 0 LHGDN
Rett Syndrome 0.00272435 1 0 LHGDN
Sarcoma 0.00272435 1 0 LHGDN
Attention deficit hyperactivity disorder 0.002367032 1 0 GAD
Kidney Failure, Chronic 0.001085767 4 0 BeFree
Chronic kidney disease stage 5 0.000814326 3 0 BeFree
Glioma 0.000542884 2 0 BeFree
Ovarian Carcinoma 0.000542884 2 0 BeFree
Kidney Failure 0.000542884 2 0 BeFree
Central neuroblastoma 0.000542884 2 0 BeFree
Liver carcinoma 0.000542884 2 0 BeFree
Diabetic Nephropathy 0.000271442 1 0 BeFree
Diabetic Retinopathy 0.000271442 1 0 BeFree
Hyperlipidemia 0.000271442 1 0 BeFree
Intestinal Diseases 0.000271442 1 0 BeFree
Retinoblastoma 0.000271442 1 0 BeFree
Systemic Scleroderma 0.000271442 1 0 BeFree
B-Cell Lymphomas 0.000271442 1 0 BeFree
Peripheral T-Cell Lymphoma 0.000271442 1 0 BeFree
Ki-1+ Anaplastic Large Cell Lymphoma 0.000271442 1 0 BeFree
Dyslipidemias 0.000271442 1 0 BeFree
Impaired cognition 0.000271442 1 0 BeFree
Malignant neoplasm of prostate 0.000271442 1 0 BeFree
Overweight 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
ovarian neoplasm 0.000271442 1 0 BeFree
Classical Hodgkin's Lymphoma 0.000271442 1 0 BeFree
Epithelioma 0.000271442 1 0 BeFree
T-Cell Prolymphocytic Leukemia 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

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