CYP27B1(cytochrome P450, family 27, subfamily B, polypeptide 1)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

12q14.1
基因染色体位置图

基因简述

基因简述

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因编码的酶的细胞色素P450超家族的成员。细胞色素P450蛋白是能催化涉及药物代谢和胆固醇，类固醇和其他脂类的合成许多反应单加氧酶。由该基因编码的蛋白质定位于线粒体内膜的地方羟化25-羟基维生素D3在1α的位置。这个反应来合成1α的，25二羟基维生素D3，维生素D3，其结合到维生素D受体和调节钙的代谢活性形式。因此，这个酶调节生物活性的维生素D的水平和起着钙稳态中起重要作用。在这个基因的突变可导致维生素D依赖性佝偻病I型[由RefSeq的，2008年7月提供]

OMIM数据库中对CYP27B1基因的介绍     Wikipedia数据库中对CYP27B1基因的介绍

基因序列

基因序列

CYP27B1基因的碱基序列：[NCBI]

基因突变

基因突变

CYP27B1基因的碱基突变：           显示全部snp
rs703842       rs2229103       rs2307096       rs2427640       rs2454751       rs3782130       rs4646536       rs4646537       rs7965963       rs8176339       rs8176340       rs8176342       rs8176343       rs8176344       rs8176345       rs8176346       rs8176347       rs8176348       rs8176349       rs8176350       rs8176351       rs8176352       rs10877012       rs11172326       rs11172327       rs28934606       rs35569378       rs41325246       rs58915677       rs61734540       rs73338256       rs74679406       rs78060713       rs79741632       rs111235166       rs111503667       rs111629101      
rs113298639       rs113812164       rs114062320       rs115631506       rs117629275       rs117864436       rs118204008       rs118204009       rs118204010       rs118204012       rs138233467       rs139289916       rs139558307       rs140194153       rs141241519       rs141820034       rs141890302       rs141906701       rs141927200       rs142121467       rs142446425       rs143165542       rs143950447       rs145339059       rs145618370       rs145643125       rs145790221       rs145819242       rs146281435       rs147119803       rs147713752       rs147755108       rs147773762       rs147949367       rs148336763       rs148627073       rs149518825       rs149829610       rs150025067       rs150232512       rs150334927       rs150648140       rs151335249       rs180727885       rs180865889       rs181180650       rs181566198       rs182661200       rs183213602       rs184252745       rs184277621       rs184727850       rs185641454       rs185769797       rs186563047       rs187486670       rs188819808       rs189295818       rs189557481       rs190351633       rs190470241       rs190694526       rs191239138       rs191727255       rs192018061       rs199565614       rs199575147       rs199711056       rs199923824       rs200174985       rs200191262       rs200265154       rs200567715       rs200703167       rs200761229       rs201190359       rs201302886       rs201343041       rs201484091       rs201503366       rs201534673       rs201629800       rs201673849       rs201819682       rs201869290       rs202028173       rs202032208       rs367743385       rs367795485       rs367888907       rs368069805       rs368126466       rs368166625       rs368234045       rs368285948       rs368820787       rs369223883       rs369374170       rs369510241       rs369549262       rs370198750       rs370689065       rs370743468       rs370850634       rs371587860       rs371594650       rs371735439       rs371880778       rs372020956       rs372223837       rs372269276       rs372422608       rs372527928       rs372771210       rs372846214       rs372885773       rs373454823       rs373542360       rs373561653       rs373607899       rs373672754       rs373919730       rs374376984       rs374454037       rs374481894       rs374536920       rs374681375       rs374882356       rs375741542       rs376212738       rs376304260       rs377154743       rs377397604       rs387906260       rs528272567       rs528324914       rs528489670       rs528531210       rs528790580       rs529118144       rs529281234       rs529564139       rs529652407       rs529738756       rs530008944       rs530143836       rs530682562       rs530991189       rs531029924       rs531437421       rs531984918       rs532070975       rs532144928       rs532181970       rs533152224       rs533410734       rs533718329       rs534101281       rs534888826       rs535213718       rs535347844       rs535463729       rs535632215       rs536111659       rs536124873       rs536827929       rs537715358       rs537778921       rs537825066       rs538399116       rs538719019       rs538945449       rs539158689       rs539747491       rs540073114       rs540413616       rs540725569       rs541475094       rs541862009       rs542864064       rs542906068       rs544017985       rs544219775       rs544445921       rs544560458       rs545464947       rs545558315       rs546364438       rs546369087       rs546648396       rs547263897       rs547387731       rs547565211       rs547898932       rs548176807       rs548627735       rs548688407       rs548689318       rs549726296       rs549824639       rs549863375       rs550296848       rs551616538       rs551974141       rs552623342       rs554101223       rs554141410       rs554748940       rs555068245       rs555279227       rs556146256       rs556234365       rs556272855       rs556493554       rs556530774       rs556635359       rs557054384       rs557294448       rs557297762       rs557461860       rs560778422       rs561296392       rs561541172       rs561951133       rs562210715       rs562644428       rs562671945       rs562916792       rs563225181       rs563744441       rs563754194       rs563980121       rs564733199       rs564954189       rs565490799       rs565963580       rs566560822       rs567195245       rs567237244       rs568165874       rs568414896       rs568598978       rs568607776       rs568628584       rs568645777       rs569065283       rs569709279       rs569877712       rs570021066       rs570033449       rs570110170       rs570777302       rs570812416       rs570897771       rs571082817       rs571216261       rs571305583       rs571422853       rs572466704       rs572765133       rs573538895       rs574099143       rs574469695       rs574923298       rs575023066       rs575259227       rs575378164       rs576741401       rs576826652       rs577036725       rs577501884       rs577603625       rs577642812       rs578010655       rs745388058       rs745516871       rs745544786       rs745571910       rs745723541       rs745757851       rs745855640       rs745971801       rs746019534       rs746021709       rs746144650       rs746153660       rs746253099       rs746345633       rs746424645       rs746773160       rs746835944       rs746877889       rs747106578       rs747135985       rs747182796       rs747235060       rs747414915       rs747732728       rs747734371       rs748058985       rs748104349       rs748241510       rs748385650       rs748472549       rs748494534       rs748602968       rs748748564       rs748833551       rs748833715       rs748901730       rs748991170       rs749017261       rs749181794       rs749184039       rs749194445       rs749254542       rs749448463       rs749537609       rs749577015       rs749745310       rs749948148       rs749966401       rs750002391       rs750115347       rs750314936       rs750450741       rs750468088       rs750773217       rs750827656       rs750908103       rs751048270       rs751164864       rs751211606       rs751252853       rs751262543       rs751386712       rs751574733       rs751587630       rs751606502       rs751768889       rs751820138       rs751848951       rs751953236       rs752016201       rs752137935       rs752175742       rs752406850       rs752504237       rs752540318       rs752547385       rs752594802       rs752696414       rs752697207       rs752926249       rs752977580       rs753086020       rs753152890       rs753206974       rs753354343       rs753488803       rs753678470       rs753685834       rs753733417       rs753823609       rs753888767       rs753898222       rs753998021       rs754122776       rs754260658       rs754435549       rs754449343       rs754452515       rs754559171       rs754595210       rs754619955       rs754851750       rs754869778       rs754963151       rs755018398       rs755142592       rs755402663       rs755512223       rs755654732       rs755756036       rs755791839       rs755816133       rs755845434       rs755878350       rs755956057       rs756054548       rs756066635       rs756141743       rs756226286       rs756300813       rs756495841       rs756788811       rs756926294       rs756958202       rs757230927       rs757277620       rs757283928       rs757358360       rs757388190       rs757436195       rs757673918       rs757777816       rs757859131       rs758021519       rs758053526       rs758216478       rs758218175       rs758271238       rs758508383       rs758546382       rs758671027       rs758703209       rs758749494       rs758802757       rs758931129       rs758987779       rs759053239       rs759056278       rs759208930       rs759285613       rs759331498       rs759410154       rs759563696       rs759569512       rs759805058       rs759821430       rs759844657       rs759915706       rs759986559       rs760020111       rs760071258       rs760233049       rs760297586       rs760548148       rs760753732       rs760965198       rs761123158       rs761134567       rs761149528       rs761183667       rs761210130       rs761365991       rs761605625       rs761620743       rs761780097       rs761803324       rs761902845       rs762038212       rs762118198       rs762473406       rs762550487       rs762555680       rs762682469       rs762684209       rs762701380       rs762735324       rs762823879       rs762847002       rs762932963       rs763136429       rs763171658       rs763284949       rs763440268       rs763451961       rs763534112       rs763656534       rs763769990       rs764004209       rs764038309       rs764141450       rs764196493       rs764387303       rs764582398       rs764669573       rs764734028       rs765139748       rs765161769       rs765241743       rs765302413       rs765368858       rs765408119       rs765532756       rs765572208       rs765578869       rs765795630       rs765809691       rs765846783       rs765853566       rs766031177       rs766037385       rs766108107       rs766306920       rs766418508       rs766452283       rs766532462       rs766538924       rs766852711       rs767083686       rs767085633       rs767152707       rs767201145       rs767253913       rs767480544       rs767516163       rs767653406       rs767679343       rs767869773       rs767989731       rs768158988       rs768276712       rs768371974       rs768373645       rs768601263       rs768660808       rs768815155       rs768855649       rs768857789       rs768893540       rs768968235       rs769013170       rs769363080       rs769405152       rs769487954       rs769534483       rs769591385       rs769593161       rs769831959       rs770031341       rs770079607       rs770204470       rs770422448       rs770470667       rs770528985       rs770581711       rs770746377       rs770828560       rs770873791       rs770886393       rs771091009       rs771151644       rs771179004       rs771215877       rs771340739       rs771410002       rs771598984       rs771667331       rs771720639       rs771825668       rs771838478       rs772097552       rs772102893       rs772171082       rs772209037       rs772355553       rs772383081       rs772434439       rs772608705       rs772650262       rs772736324       rs772846974       rs772898470       rs772960103       rs772982189       rs773153213       rs773312973       rs773431013       rs773502563       rs773538942       rs773724344       rs773837002       rs773986669       rs774009424       rs774051629       rs774100842       rs774153859       rs774455044       rs774541604       rs774677094       rs774677732       rs774690200       rs774732743       rs774849834       rs774932003       rs775114472       rs775212158       rs775231921       rs775461299       rs775708027       rs775761188       rs775810183       rs775812483       rs775815261       rs775865565       rs775976633       rs776399364       rs776405578       rs776510825       rs776536884       rs776560698       rs776656881       rs776724658       rs776942384       rs777022503       rs777245297       rs777419232       rs777427466       rs777428292       rs777477723       rs777511586       rs777588673       rs777612495       rs777699465       rs778091400       rs778225054       rs778438734       rs778531241       rs778835851       rs778903870       rs778942273       rs778966424       rs779137478       rs779138180       rs779295082       rs779382219       rs779510099       rs779577823       rs779631626       rs779651723       rs779713965       rs780169018       rs780269626       rs780275124       rs780280592       rs780328425       rs780429096       rs780440003       rs780623929       rs780857122       rs780905387       rs780950819       rs781014540       rs781068197       rs781119946       rs781353865       rs781643975      

基因表达

基因表达

CYP27B1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CTCTTCCCTTTGGCTTTGG
59
ATGTGTTAGGATCTGGGCC
59
CTTAAAGAAGGTGCAGGGC
59
GAGCCTTTGCCATTCTTCG
60
CCTCGACCGAGATGATCAG
60
GAGCCTTTGCCATTCTTCG
60
TCTCTTAAAGAAGGTGCAGGG
60
GAGCCTTTGCCATTCTTCG
60
CCAGGTATCCAAGTGTCCG
60
GAGCCTTTGCCATTCTTCG
60
TGTTTGCATTTGCTCAGAGG
60
CAGACTCCAGGTCCTTCTC
59
TTGGCCCAGATCCTAACAC
59
TTTCAGGTACCAGGACAGTC
59
TCGACCGAGATGATCAGAG
58
GAGCCTTTGCCATTCTTCG
60
CCCAGGTATCCAAGTGTCC
60
GAGCCTTTGCCATTCTTCG
60
ACTCAGAGATCACAGCTGC
60
ACAGGGTACAGTCTTAGCAC
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

CYP27B1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CYP27B1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0004497
F8VWR7(UniProtKB)
IEA
GO:0005506
F8VWR7(UniProtKB)
IEA
GO:0016705
F8VWR7(UniProtKB)
IEA
GO:0020037
F8VWR7(UniProtKB)
IEA
GO:0055114
F8VWR7(UniProtKB)
IEA
GO:0004498
O15528(UniProtKB)
IDA
GO:0004498
O15528(UniProtKB)
IDA
GO:0004498
O15528(UniProtKB)
IDA
GO:0004498
O15528(UniProtKB)
IDA
GO:0004498
O15528(UniProtKB)
TAS
GO:0005506
O15528(UniProtKB)
IEA
GO:0005737
O15528(UniProtKB)
IDA
GO:0005737
O15528(UniProtKB)
IDA
GO:0005739
O15528(UniProtKB)
ISS
GO:0005739
O15528(UniProtKB)
TAS
GO:0005741
O15528(UniProtKB)
TAS
GO:0006766
O15528(UniProtKB)
TAS
GO:0006816
O15528(UniProtKB)
ISS
GO:0008285
O15528(UniProtKB)
IDA
GO:0010956
O15528(UniProtKB)
IDA
GO:0010980
O15528(UniProtKB)
IDA
GO:0020037
O15528(UniProtKB)
IEA
GO:0030282
O15528(UniProtKB)
IEP
GO:0030308
O15528(UniProtKB)
IMP
GO:0030500
O15528(UniProtKB)
IMP
GO:0032496
O15528(UniProtKB)
IDA
GO:0033280
O15528(UniProtKB)
IDA
GO:0034341
O15528(UniProtKB)
IDA
GO:0036378
O15528(UniProtKB)
IDA
GO:0036378
O15528(UniProtKB)
IDA
GO:0036378
O15528(UniProtKB)
IDA
GO:0036378
O15528(UniProtKB)
IDA
GO:0042359
O15528(UniProtKB)
IDA
GO:0042359
O15528(UniProtKB)
TAS
GO:0042369
O15528(UniProtKB)
IEA
GO:0043627
O15528(UniProtKB)
IEP
GO:0045618
O15528(UniProtKB)
IMP
GO:0046697
O15528(UniProtKB)
IEP
GO:0055074
O15528(UniProtKB)
IMP
GO:0055114
O15528(UniProtKB)
IEA
GO:0070314
O15528(UniProtKB)
IMP
GO:0070564
O15528(UniProtKB)
IDA
GO:0005506
V9GYP0(UniProtKB)
IEA
GO:0016705
V9GYP0(UniProtKB)
IEA
GO:0020037
V9GYP0(UniProtKB)
IEA
GO:0055114
V9GYP0(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控CYP27B1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Vitamin D-dependent rickets, type 1 0.445428837 22 14 BeFree_CLINVAR_CTD_human_MGD_UNIPROT
Multiple Sclerosis 0.132258492 21 1 BeFree_GAD_GWASCAT
Rickets 0.125428837 21 0 BeFree_CTD_human
Hypercalcemia 0.121085767 5 0 BeFree_CTD_human
Polymyositis 0.12 1 0 CTD_human
Acidosis 0.08 1 0 RGD
Diabetes Mellitus, Experimental 0.08 1 0 RGD
Hepatolenticular Degeneration 0.08 1 0 RGD
Nephrosis 0.08 1 0 RGD
Acute kidney injury 0.08 1 0 RGD
Malignant neoplasm of prostate 0.025407253 52 0 BeFree_GAD
Diabetes Mellitus, Insulin-Dependent 0.021573392 52 2 BeFree_GAD_LHGDN
Osteoporosis 0.016567886 52 0 BeFree_LHGDN
Prostate carcinoma 0.014114977 52 0 BeFree
Breast Carcinoma 0.013843535 51 0 BeFree
Malignant neoplasm of breast 0.013572094 50 0 BeFree
Prostatic Neoplasms 0.011168843 5 0 BeFree_LHGDN
Hashimoto Disease 0.01099709 5 0 BeFree_GAD_LHGDN
Diabetes Mellitus, Non-Insulin-Dependent 0.009705894 17 0 BeFree_GAD_LHGDN
Graves Disease 0.009544073 11 0 BeFree_GAD
Autoimmune Diseases 0.007881746 19 0 BeFree_LHGDN
Colorectal Cancer 0.006786047 25 0 BeFree
Vitamin D Deficiency 0.006710102 17 0 BeFree_GAD
Colorectal Carcinoma 0.006514605 24 0 BeFree
Colonic Neoplasms 0.00554839 5 0 BeFree_GAD
Addison Disease 0.004734064 2 0 GAD
Asthma 0.004538567 8 0 BeFree_GAD
Tuberculosis 0.004071628 15 0 BeFree
Hypertensive disease 0.003995683 6 0 BeFree_GAD
Glioblastoma 0.003810118 4 0 BeFree_LHGDN
melanoma 0.003800186 14 9 BeFree
Tuberculosis, Pulmonary 0.003800186 14 0 BeFree
Lupus Erythematosus, Systemic 0.003528744 13 0 BeFree
Colon Carcinoma 0.003528744 13 0 BeFree
Diabetic Nephropathy 0.003452799 4 0 BeFree_GAD
Malignant neoplasm of lung 0.003452799 5 0 BeFree_GAD
Coronary Artery Disease 0.003452799 5 0 BeFree_GAD
Epithelial ovarian cancer 0.003181358 4 0 BeFree_GAD
Mammary Neoplasms 0.002995792 2 0 BeFree_LHGDN
Malignant tumor of colon 0.002985861 11 0 BeFree
Gestational Diabetes 0.002909916 3 0 BeFree_GAD
Dysgerminoma 0.00272435 1 0 LHGDN
Lung Neoplasms 0.00272435 1 0 LHGDN
Ovarian Carcinoma 0.002442977 9 0 BeFree
Malignant neoplasm of ovary 0.002442977 9 0 BeFree
Calcinosis 0.002367032 1 0 GAD
Heart failure 0.002367032 1 0 GAD
Chronic Obstructive Airway Disease 0.002367032 1 0 GAD
Autoimmune thyroiditis 0.002367032 1 0 GAD
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 0.002367032 1 0 GAD
Diabetes Mellitus 0.002171535 8 0 BeFree
Hyperparathyroidism 0.002171535 8 0 BeFree
Kidney Failure, Chronic 0.002171535 8 0 BeFree
Carcinogenesis 0.002171535 8 0 BeFree
Rectal Carcinoma 0.001900093 7 2 BeFree
Renal Cell Carcinoma 0.001900093 7 0 BeFree
Obesity 0.001900093 7 0 BeFree
Periodontitis 0.001900093 7 0 BeFree
Chronic Periodontitis 0.001900093 7 0 BeFree
Urolithiasis 0.001900093 7 1 BeFree
Rheumatoid Arthritis 0.001628651 6 0 BeFree
Crohn Disease 0.001628651 6 0 BeFree
Diabetes 0.001628651 6 0 BeFree
Gingival Diseases 0.001628651 6 0 BeFree
Hyperparathyroidism, Secondary 0.001628651 6 0 BeFree
Periodontal Diseases 0.001628651 6 0 BeFree
Periodontitis, Juvenile 0.001628651 6 0 BeFree
Tumor Progression 0.001628651 6 0 BeFree
Benign Prostatic Hyperplasia 0.001628651 6 0 BeFree
Liver carcinoma 0.001628651 6 0 BeFree
Chronic kidney disease stage 5 0.001628651 6 0 BeFree
Ulcerative Colitis 0.001357209 5 0 BeFree
Inflammatory Bowel Diseases 0.001357209 5 0 BeFree
Degenerative polyarthritis 0.001357209 5 0 BeFree
Psoriasis 0.001357209 5 0 BeFree
Carcinoma of lung 0.001357209 5 0 BeFree
Malignant neoplasm of skin 0.001085767 4 0 BeFree
Squamous cell carcinoma 0.001085767 4 1 BeFree
HIV Infections 0.001085767 4 0 BeFree
Neoplasm Metastasis 0.001085767 4 0 BeFree
Metabolic Syndrome X 0.001085767 4 0 BeFree
Hepatitis C, Chronic 0.001085767 4 1 BeFree
Chronic Kidney Diseases 0.001085767 4 0 BeFree
Behcet Syndrome 0.000814326 3 0 BeFree
Non-Small Cell Lung Carcinoma 0.000814326 3 0 BeFree
Glioma 0.000814326 3 0 BeFree
Hepatitis B 0.000814326 3 0 BeFree
Acute Promyelocytic Leukemia 0.000814326 3 0 BeFree
Lung diseases 0.000814326 3 0 BeFree
Osteoporosis, Postmenopausal 0.000814326 3 0 BeFree
Ovarian Diseases 0.000814326 3 0 BeFree
Kidney Failure 0.000814326 3 0 BeFree
Sarcoidosis 0.000814326 3 0 BeFree
Intervertebral Disc Degeneration 0.000814326 3 0 BeFree
Hyperparathyroidism, Primary 0.000814326 3 0 BeFree
Psoriasis vulgaris 0.000814326 3 0 BeFree
Early onset periodontitis 0.000814326 3 0 BeFree
Adenoma of large intestine 0.000814326 3 0 BeFree
Sporadic Breast Carcinoma 0.000814326 3 0 BeFree
Glioblastoma Multiforme 0.000814326 3 0 BeFree
Experimental Organism Basal Cell Carcinoma 0.000814326 3 1 BeFree
Acquired Immunodeficiency Syndrome 0.000542884 2 0 BeFree
Adenoma 0.000542884 2 0 BeFree
Cooley's anemia 0.000542884 2 0 BeFree
Bone Diseases 0.000542884 2 0 BeFree
Calcium Metabolism Disorders 0.000542884 2 0 BeFree
Malignant tumor of cervix 0.000542884 2 0 BeFree
Primary biliary cirrhosis 0.000542884 2 0 BeFree
Diabetic Retinopathy 0.000542884 2 0 BeFree
Eczema 0.000542884 2 0 BeFree
External exotoses 0.000542884 2 0 BeFree
Liver Cirrhosis 0.000542884 2 0 BeFree
Liver diseases 0.000542884 2 0 BeFree
Mitral Valve Stenosis 0.000542884 2 0 BeFree
Parathyroid Neoplasms 0.000542884 2 0 BeFree
Polycystic Ovary Syndrome 0.000542884 2 0 BeFree
Ankylosing spondylitis 0.000542884 2 0 BeFree
Thyroiditis 0.000542884 2 0 BeFree
Turner Syndrome 0.000542884 2 0 BeFree
Uveitis 0.000542884 2 0 BeFree
Vitiligo 0.000542884 2 0 BeFree
Tooth Loss 0.000542884 2 0 BeFree
Cutaneous Melanoma 0.000542884 2 0 BeFree
Secondary malignant neoplasm of bone 0.000542884 2 0 BeFree
Autoimmune thyroid disease 0.000542884 2 0 BeFree
Vitamin D-dependent rickets 0.000542884 2 0 BeFree
Pancreatic carcinoma 0.000542884 2 0 BeFree
Hepatitis, Autoimmune 0.000542884 2 0 BeFree
Parathyroid Adenoma 0.000542884 2 0 BeFree
Cervix carcinoma 0.000542884 2 0 BeFree
Vitamin D-Dependent Rickets, Type 2A 0.000542884 2 0 BeFree
Malignant neoplasm of pancreas 0.000542884 2 0 BeFree
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site 0.000542884 2 0 BeFree
Nephrolithiasis 0.000542884 2 0 BeFree
Primary osteoporosis 0.000542884 2 0 BeFree
Neurodegenerative Disorders 0.000542884 2 0 BeFree
Hepatitis B, Chronic 0.000542884 2 0 BeFree
Idiopathic hypercalciuria 0.000542884 2 0 BeFree
Thyroid carcinoma 0.000542884 2 0 BeFree
Malignant Glioma 0.000542884 2 0 BeFree
Differentiated Thyroid Gland Carcinoma 0.000542884 2 7 BeFree
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) 0.000542884 2 0 BeFree
Osteophyte 0.000542884 2 0 BeFree
Prostate cancer, familial 0.000542884 2 0 BeFree
Familial Hypophosphatemic Rickets 0.000542884 2 0 BeFree
Adenocarcinoma 0.000271442 1 0 BeFree
Anemia 0.000271442 1 0 BeFree
Arthralgia 0.000271442 1 0 BeFree
Barrett Esophagus 0.000271442 1 0 BeFree
Bladder Neoplasm 0.000271442 1 0 BeFree
Bronchopulmonary Dysplasia 0.000271442 1 0 BeFree
Cachexia 0.000271442 1 0 BeFree
Malignant neoplasm of thyroid 0.000271442 1 0 BeFree
Celiac Disease 0.000271442 1 0 BeFree
Cholestasis 0.000271442 1 0 BeFree
Choriocarcinoma 0.000271442 1 0 BeFree
Colitis 0.000271442 1 0 BeFree
Coronary Arteriosclerosis 0.000271442 1 0 BeFree
Coronary heart disease 0.000271442 1 0 BeFree
Dermatitis, Atopic 0.000271442 1 0 BeFree
Eosinophilia 0.000271442 1 0 BeFree
Female Genital Diseases 0.000271442 1 0 BeFree
Congestive heart failure 0.000271442 1 0 BeFree
Severe Dengue 0.000271442 1 0 BeFree
Hip Dislocation, Congenital 0.000271442 1 0 BeFree
Hypercalciuria 0.000271442 1 0 BeFree
Hyperthyroidism 0.000271442 1 0 BeFree
Hypoparathyroidism 0.000271442 1 0 BeFree
Keloid 0.000271442 1 0 BeFree
Keratosis 0.000271442 1 0 BeFree
Actinic keratosis 0.000271442 1 0 BeFree
leukemia 0.000271442 1 0 BeFree
Liver Cirrhosis, Alcoholic 0.000271442 1 0 BeFree
Liver neoplasms 0.000271442 1 0 BeFree
Lymphoma, Non-Hodgkin 0.000271442 1 0 BeFree
Malaria 0.000271442 1 0 BeFree
Malaria, Vivax 0.000271442 1 0 BeFree
Measles 0.000271442 1 0 BeFree
Metabolic Diseases 0.000271442 1 1 BeFree
Mycoses 0.000271442 1 0 BeFree
Neuromyelitis Optica 0.000271442 1 0 BeFree
Osteomalacia 0.000271442 1 0 BeFree
Parkinson Disease 0.000271442 1 0 BeFree
Psychotic Disorders 0.000271442 1 0 BeFree
Retinal Diseases 0.000271442 1 0 BeFree
Septicemia 0.000271442 1 0 BeFree
Thalassemia 0.000271442 1 0 BeFree
Uremia 0.000271442 1 0 BeFree
Uterine Fibroids 0.000271442 1 0 BeFree
Lymphoma, Large-Cell, Follicular 0.000271442 1 0 BeFree
Depressive Symptoms 0.000271442 1 0 BeFree
Left Ventricular Hypertrophy 0.000271442 1 0 BeFree
Humoral hypercalcemia of malignancy (disorder) 0.000271442 1 0 BeFree
Adenocarcinoma of lung (disorder) 0.000271442 1 0 BeFree
Malignant neoplasm of gallbladder 0.000271442 1 0 BeFree
Infections, Hospital 0.000271442 1 0 BeFree
Tuberculosis, Multidrug-Resistant 0.000271442 1 0 BeFree
Follicular thyroid carcinoma 0.000271442 1 7 BeFree
Cholangiocarcinoma 0.000271442 1 0 BeFree
Gallbladder Carcinoma 0.000271442 1 0 BeFree
Papillary thyroid carcinoma 0.000271442 1 7 BeFree
Acute lower respiratory tract infection 0.000271442 1 0 BeFree
Fibrosis, Liver 0.000271442 1 0 BeFree
Sepsis 0.000271442 1 0 BeFree
Osteoarthritis of the hand 0.000271442 1 0 BeFree
Hypercalcemia, Idiopathic, of Infancy 0.000271442 1 0 BeFree
Tertiary hyperparathyroidism 0.000271442 1 0 BeFree
Cancer of Head and Neck 0.000271442 1 0 BeFree
Liver and Intrahepatic Biliary Tract Carcinoma 0.000271442 1 0 BeFree
Squamous cell carcinoma of esophagus 0.000271442 1 0 BeFree
Conventional (Clear Cell) Renal Cell Carcinoma 0.000271442 1 0 BeFree
Solid tumour 0.000271442 1 0 BeFree
stage, non-small cell lung cancer 0.000271442 1 0 BeFree
Restenosis 0.000271442 1 0 BeFree
Chronic liver disease 0.000271442 1 0 BeFree
Malignant neoplasm of liver 0.000271442 1 0 BeFree
Nonorganic psychosis 0.000271442 1 0 BeFree
Osteoarthritis of distal interphalangeal joint 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
Atrichia 0.000271442 1 0 BeFree
Malignant neoplasm of kidney 0.000271442 1 0 BeFree
early pregnancy 0.000271442 1 0 BeFree
Plasmodium vivax infection 0.000271442 1 0 BeFree
ovarian neoplasm 0.000271442 1 0 BeFree
Ischemic stroke 0.000271442 1 0 BeFree
Denys-Drash Syndrome 0.000271442 1 0 BeFree
Heart Failure, Systolic 0.000271442 1 0 BeFree
Eosinophilic disorder 0.000271442 1 0 BeFree
Renal carcinoma 0.000271442 1 0 BeFree
Cervical spondylosis 0.000271442 1 0 BeFree
Sjogren's Syndrome 0.000271442 1 0 BeFree
Nephrogenic Fibrosing Dermopathy 0.000271442 1 0 BeFree
Cirrhosis 0.000271442 1 0 BeFree
Disorder characterized by eosinophilia 0.000271442 1 0 BeFree
Hypophosphatemic Rickets 0.000271442 1 0 BeFree
Aggressive periodontitis, generalized 0.000271442 1 0 BeFree
Slow acetylator due to N-acetyltransferase enzyme variant 0.000271442 1 0 BeFree
Mammographic Density 0.000271442 1 0 BeFree
ATRICHIA WITH PAPULAR LESIONS 0.000271442 1 0 BeFree
Syndactyly, Type IV 0.000271442 1 0 BeFree
Vitamin D-resistant rickets 0.000271442 1 0 BeFree
Ischemic Cerebrovascular Accident 0.000271442 1 0 BeFree
Juvenile arthritis 0.000271442 1 0 BeFree
Juvenile rheumatoid arthritis 0.000271442 1 0 BeFree
AIDS (Disease) 0.000271442 1 0 BeFree

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