CCL14(chemokine (C-C motif) ligand 14)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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17q12
基因染色体位置图

This gene, chemokine (C-C motif) ligand 14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Read-through transcripts are also expressed that include exons from the upstream cytokine gene, chemokine (C-C motif) ligand 15, and are represented as GeneID: 348249. [provided by RefSeq, Dec 2009]

[中文简述(自动翻译):]  该基因,趋化因子(C-C基序)配体14,是聚集在17q11.2几个CC细胞因子基因之一。在CC细胞因子分泌特征在于两个相邻的半胱氨酸的蛋白质。由该基因编码的细胞因子诱导的细胞内钙离子浓度和单核细胞中酶的释放的变化。已发现该基因编码不同亚型的多个抄本变形。通读成绩单也表示,包括从上游细胞因子基因,趋化因子(C-C基序)配体15个外显子,并表示为GeneID:348249. [由提供RefSeq的,2009年12月]

CCL14基因的碱基序列:[NCBI]
CCL14基因的碱基突变:           显示全部snp
rs854681       rs854682       rs854683       rs854684       rs2376291       rs9892586       rs9895622       rs9903158       rs10491118       rs12051658       rs16971802       rs28562154       rs41341749       rs41396745       rs41495150       rs55913087       rs71381488       rs72830000       rs75238886       rs76190126       rs77812652       rs78339459       rs111856180       rs112067627       rs112144652       rs112801225       rs113167429       rs113264703       rs113271725       rs113323375       rs113715327       rs113937434       rs114534185       rs114667032       rs114860887       rs116117954       rs116561020      
rs116951728       rs117769679       rs139002794       rs139236989       rs139591348       rs139891933       rs140323423       rs141068719       rs141746991       rs142032662       rs142226603       rs142973175       rs143984784       rs144024677       rs144484477       rs144903710       rs145557095       rs146230281       rs147465786       rs148605501       rs149683495       rs150356706       rs151187428       rs180746451       rs181313269       rs181810445       rs182290628       rs183367107       rs185259562       rs185353235       rs185710428       rs186319838       rs186638536       rs186783049       rs188121858       rs189263398       rs189454096       rs190206079       rs191159477       rs191611254       rs191627296       rs192665935       rs199677295       rs200023895       rs200414520       rs200417454       rs200944789       rs201876342       rs201904488       rs267604821       rs368096078       rs368511619       rs368558372       rs368560391       rs370183552       rs372084156       rs372776364       rs372808751       rs373690478       rs374433864       rs375335603       rs375806651       rs376131777       rs376902531       rs377214495       rs377492493       rs527308491       rs527676094       rs532266388       rs533108651       rs533374526       rs533731552       rs534394820       rs534466982       rs535658859       rs535950329       rs536384701       rs538168002       rs538474587       rs539097738       rs539718997       rs540009368       rs540714156       rs541004599       rs543317054       rs543579766       rs544618157       rs544624203       rs544800293       rs545432934       rs545849066       rs546128160       rs546415783       rs546674867       rs546741985       rs547509478       rs547632175       rs547822806       rs550017018       rs552590449       rs553587150       rs554183634       rs554603821       rs555038059       rs555055366       rs555296098       rs557289946       rs557494863       rs559254462       rs559430822       rs561321379       rs561575067       rs561634027       rs562594811       rs564057704       rs564222891       rs564393907       rs565432558       rs565748095       rs568571204       rs569650810       rs569877273       rs570593838       rs571663455       rs572084676       rs573007835       rs573773486       rs575162341       rs575540090       rs575550636       rs575574172       rs576252349       rs577388120       rs577526242       rs577586489       rs745481745       rs745567030       rs745662062       rs745843281       rs746117053       rs746518735       rs747048760       rs747684916       rs747945816       rs747972780       rs748305457       rs748342503       rs749195974       rs749370651       rs749600684       rs749838384       rs749928155       rs750105376       rs750312238       rs750620028       rs750764406       rs751441115       rs751520401       rs751828166       rs752054021       rs752405532       rs752706416       rs752792314       rs753086467       rs753458266       rs754288246       rs754565224       rs754659661       rs755332753       rs755690324       rs756002151       rs756649752       rs756791003       rs756806176       rs756962710       rs757749260       rs757932519       rs758247502       rs758615336       rs758625087       rs758839337       rs759752973       rs760105291       rs760207812       rs760615419       rs760720856       rs760762528       rs760999443       rs761476803       rs761714524       rs762190316       rs762566140       rs762669764       rs763317253       rs763925611       rs763931960       rs764281468       rs764479790       rs765132575       rs765859167       rs765869165       rs766861038       rs767346222       rs767425052       rs767642183       rs767817015       rs768486408       rs768680560       rs769002637       rs769035837       rs769854730       rs769999128       rs770215339       rs770664855       rs770936645       rs770986117       rs771055321       rs771308300       rs771429403       rs771441014       rs771646249       rs771786113       rs772303027       rs772924502       rs773052358       rs773406284       rs773777488       rs773974201       rs774100370       rs774176336       rs774186088       rs775000350       rs775087719       rs775196978       rs775413064       rs775571388       rs775693566       rs776179057       rs776439940       rs776724447       rs777385639       rs778350631       rs778815719       rs778927371       rs779124679       rs779464556       rs779582229       rs780531610       rs780632165       rs780826457       rs781664854      

CCL14基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AGACTGAATCCTCCTCACG
59
GTGATGAAGACAATTCCGGG
59
ATCCTCCTCACAAACTGGG
59
TAGGTGAAGCAGCACTCTG
59
CGGAATTGTCTTCATCACCA
58
TCCTTGATATAGTCCTGGACC
58
GACTGAATCCTCCTCACGG
60
GTGATGAAGACAATTCCGGG
59
CTACCTACAAGATCCCGCG
59
GGTGATGAAGCTACACAATTCC
59
AATCCTCCTCACAAACTGGG
60
TAGGTGAAGCAGCACTCTG
59
ATCCTCCTCACAAACTGGG
59
TGTAGGTGAAGCAGCACTC
60
CTACCTACAAGATCCCGCG
60
GGTGATGAAGCTACACAATTCC
60
CCCGGAATTGTCTTCATCAC
59
CTTGATATAGTCCTGGACCCAC
60
GACTGAATCCTCCTCACGG
60
GGTGATGAAGACAATTCCGG
59
      尚未收录相关数据

CCL14基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CCL14基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0005615
A0A087X089(UniProtKB)
IEA
GO:0006955
A0A087X089(UniProtKB)
IEA
GO:0008009
A0A087X089(UniProtKB)
IEA
GO:0060326
A0A087X089(UniProtKB)
IEA
GO:0005576
A0A0B4J2G5(UniProtKB)
IEA
GO:0006955
A0A0B4J2G5(UniProtKB)
IEA
GO:0008009
A0A0B4J2G5(UniProtKB)
IEA
GO:0060326
A0A0B4J2G5(UniProtKB)
IEA
GO:0002548
Q16627(UniProtKB)
IBA
GO:0005615
Q16627(UniProtKB)
IEA
GO:0005623
Q16627(UniProtKB)
IEA
GO:0006874
Q16627(UniProtKB)
TAS
GO:0006954
Q16627(UniProtKB)
IBA
GO:0007186
Q16627(UniProtKB)
IBA
GO:0008009
Q16627(UniProtKB)
IBA
GO:0008284
Q16627(UniProtKB)
TAS
GO:0030593
Q16627(UniProtKB)
IBA
GO:0043547
Q16627(UniProtKB)
IBA
GO:0048020
Q16627(UniProtKB)
IBA
GO:0048247
Q16627(UniProtKB)
IBA
GO:0050729
Q16627(UniProtKB)
IBA
GO:0070098
Q16627(UniProtKB)
IBA
GO:0070374
Q16627(UniProtKB)
IBA
GO:0071346
Q16627(UniProtKB)
IBA
GO:0071347
Q16627(UniProtKB)
IBA
GO:0071356
Q16627(UniProtKB)
IBA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控CCL14基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Lupus Erythematosus, Systemic 0.002638474 1 0 BeFree_GAD
Asthma 0.002367032 1 0 GAD
Bronchiolitis, Viral 0.002367032 1 0 GAD
Multiple Sclerosis 0.002367032 1 0 GAD
Respiratory Syncytial Virus Infections 0.002367032 1 0 GAD
Tobacco Use Disorder 0.002367032 1 0 GAD
Liver carcinoma 0.001085767 4 0 BeFree
Liver Cirrhosis 0.000814326 3 0 BeFree
Hepatitis B 0.000542884 2 0 BeFree
Cirrhosis 0.000542884 2 0 BeFree
Astrocytoma 0.000271442 1 0 BeFree
Brain Neoplasms 0.000271442 1 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Endometriosis 0.000271442 1 0 BeFree
Inflammatory Bowel Diseases 0.000271442 1 0 BeFree
Kidney Failure, Chronic 0.000271442 1 0 BeFree
Lupus Vulgaris 0.000271442 1 0 BeFree
Lupus Erythematosus, Discoid 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Acute leukemia 0.000271442 1 0 BeFree
Adenocarcinoma of pancreas 0.000271442 1 0 BeFree
Lupus Erythematosus 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Carcinoma of lung 0.000271442 1 0 BeFree
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