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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  Wnt信号基因家族由结构相关基因,其编码分泌信号蛋白。这些蛋白质有牵连肿瘤发生并在几个发育过程,包括胚胎发育过程中细胞命运和图案化的调节。此基因是WNT基因家族的一个成员。它编码表示94%和80%的氨基酸同一性分别鼠标WNT5B蛋白和人WNT5A蛋白质,蛋白质。该基因的可变剪接产生2转录变异体。 [由RefSeq的,2008年7月提供]
WNT5B基因(以及对应的蛋白质)的细胞分布位置:
WNT5B基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Fibroid Tumor | 0.122995792 | 1 | 0 | BeFree_CTD_human_LHGDN |
| Adenoid Cystic Carcinoma | 0.12 | 1 | 0 | CTD_human |
| Salivary Gland Neoplasms | 0.12 | 1 | 0 | CTD_human |
| Diabetes Mellitus, Non-Insulin-Dependent | 0.003181358 | 3 | 0 | BeFree_GAD |
| Malignant neoplasm of breast | 0.000271442 | 1 | 0 | BeFree |
| Squamous cell carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Neoplasm Metastasis | 0.000271442 | 1 | 0 | BeFree |
| Obesity | 0.000271442 | 1 | 0 | BeFree |
| Osteosarcoma | 0.000271442 | 1 | 0 | BeFree |
| Uterine Fibroids | 0.000271442 | 1 | 0 | BeFree |
| Benign Neoplasm | 0.000271442 | 1 | 0 | BeFree |
| Recurrent tumor | 0.000271442 | 1 | 1 | BeFree |
| Osteosarcoma of bone | 0.000271442 | 1 | 0 | BeFree |
| Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
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