WNT10A(wingless-type MMTV integration site family, member 10A)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

2q35
基因染色体位置图

基因简述

基因简述

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  Wnt信号基因家族由结构相关基因，其编码分泌信号蛋白。这些蛋白质有牵连肿瘤发生并在几个发育过程，包括胚胎发育过程中细胞命运和图案化的调节。此基因是WNT基因家族的一个成员。它在早幼粒细胞白血病和伯基特淋巴瘤的细胞系中强烈表达。此外，它和其他家庭成员，WNT6基因，强烈结肠癌细胞系中共表达。基因表达可能癌变通过WNT-β-连环蛋白的TCF信号转导通路的活化中起关键作用。此基因和WNT6基因都聚集在染色体2q35区域。 [由RefSeq的，2008年7月提供]

OMIM数据库中对WNT10A基因的介绍     Wikipedia数据库中对WNT10A基因的介绍

基因序列

基因序列

WNT10A基因的碱基序列：[NCBI]

基因突变

基因突变

WNT10A基因的碱基突变：           显示全部snp
rs4674347       rs11549437       rs77272502       rs78552244       rs182186187       rs190604025       rs531076361       rs535169288       rs535783596       rs536406767       rs539901092       rs546040301       rs553337539       rs554847895       rs555773836       rs557279615       rs558860009       rs563662393       rs570627699       rs572980386       rs574740587       rs575536603       rs13205       rs1054630       rs1057306       rs2385199       rs3222974       rs3806557       rs3840475       rs3856551       rs4674346       rs6740465       rs6744926       rs7349332       rs7571600       rs7572593       rs10177996      
rs10932786       rs11680244       rs34972707       rs56677599       rs57069275       rs57897012       rs60356615       rs60449049       rs62193326       rs63111460       rs66820561       rs67367269       rs71040412       rs71040413       rs71415863       rs73084754       rs73084756       rs73084759       rs73084760       rs73084763       rs73084766       rs73084771       rs73993328       rs73993331       rs73993334       rs73993335       rs74333950       rs74625598       rs75010616       rs75259168       rs75369794       rs76923452       rs77122756       rs77420874       rs77430904       rs77583146       rs78374232       rs78397665       rs78489160       rs79316961       rs79361606       rs79447856       rs79508048       rs79621153       rs79983746       rs111547253       rs111665955       rs111696658       rs111903177       rs111921782       rs112135471       rs112240218       rs112319478       rs112761948       rs112993503       rs113224200       rs113236812       rs113239763       rs114417760       rs114813261       rs114831522       rs115091370       rs115099125       rs115326163       rs115550164       rs115572914       rs115635768       rs115685236       rs115839019       rs115921355       rs116135467       rs116590012       rs116853193       rs116998555       rs117669463       rs121908118       rs121908119       rs121908120       rs121908121       rs138277558       rs138370318       rs138548027       rs138611814       rs138747956       rs139044563       rs139882469       rs140321331       rs140458637       rs140480189       rs140665983       rs141006602       rs141074983       rs141385662       rs141593191       rs141891304       rs142584523       rs142649133       rs143248068       rs143313748       rs143399824       rs143421847       rs143424659       rs143463683       rs143927549       rs144212422       rs144478276       rs144612450       rs145190407       rs145474734       rs145641272       rs145760378       rs145817678       rs145948470       rs146201389       rs146441416       rs146460077       rs146541663       rs146571873       rs146620652       rs146902156       rs146904543       rs147026427       rs147129328       rs147145554       rs147223851       rs147680216       rs147711964       rs148187600       rs148313049       rs148401612       rs148714379       rs148979463       rs149016710       rs149189511       rs149245953       rs149286732       rs149340370       rs149816874       rs149865858       rs150744644       rs150795248       rs180692942       rs180704402       rs181197165       rs181335227       rs181397345       rs181919692       rs181949454       rs182135994       rs182648276       rs182942845       rs183193382       rs183324367       rs183479970       rs183844176       rs184217720       rs184797821       rs185202664       rs185263590       rs185315282       rs185881164       rs185886643       rs186580823       rs186705330       rs186741410       rs187451774       rs187581351       rs187588289       rs187648228       rs188041668       rs188106301       rs188260590       rs188468582       rs188882676       rs188907072       rs189146002       rs189658113       rs189966903       rs189971873       rs189995485       rs190133574       rs190368240       rs190527122       rs190737671       rs190906289       rs191137456       rs191283849       rs191464176       rs191709741       rs191997830       rs192083110       rs192432202       rs192540892       rs192662523       rs192714035       rs193098360       rs199660502       rs199737793       rs199790250       rs199802454       rs199980023       rs200233504       rs200387103       rs200446715       rs200487809       rs200657822       rs200733269       rs200751156       rs201002930       rs201117517       rs201375368       rs201578578       rs201929547       rs202024965       rs367563664       rs367808568       rs367908303       rs368280129       rs368426057       rs368482254       rs368563624       rs368750773       rs368943130       rs369027365       rs369114658       rs369533203       rs369995297       rs370107776       rs370231674       rs370462053       rs371526941       rs371642626       rs371859705       rs371998817       rs372266337       rs372538189       rs372756514       rs372993798       rs373347655       rs373607885       rs373695499       rs373803166       rs373870453       rs373991357       rs374464444       rs374771479       rs374910216       rs375166971       rs375259506       rs375577530       rs375770901       rs375819091       rs375821607       rs376559137       rs377416834       rs377503582       rs377510918       rs527286752       rs527672588       rs527797124       rs527840297       rs527886108       rs528074741       rs528163562       rs528203860       rs528284263       rs528292458       rs528307721       rs528604165       rs528733571       rs528854769       rs529100448       rs529515257       rs529604780       rs529911747       rs529919222       rs529950382       rs530036609       rs530587050       rs530628798       rs530717943       rs530730514       rs531326479       rs531633695       rs531728037       rs532280276       rs532282285       rs532365039       rs532570028       rs532784015       rs532819641       rs533064115       rs533356376       rs533380274       rs533605522       rs533712317       rs534012007       rs534172263       rs534259752       rs534341075       rs534428406       rs534585347       rs534676836       rs534838855       rs534873694       rs534874128       rs534959717       rs535468781       rs535542922       rs535557007       rs535644778       rs535946557       rs536003726       rs536310272       rs536507692       rs536548181       rs536605955       rs536755277       rs536830907       rs536912205       rs537096567       rs537117370       rs537194354       rs537314331       rs537716540       rs537719031       rs538110065       rs538146698       rs538198765       rs538201467       rs538264811       rs538392150       rs538440008       rs538674465       rs538896382       rs538939718       rs538965092       rs539490677       rs539519134       rs539782944       rs539911197       rs539926738       rs539929972       rs539978712       rs540405712       rs540496718       rs540533799       rs540564186       rs540962907       rs541050654       rs541478331       rs541715493       rs541799401       rs541887729       rs542023317       rs542193722       rs542274144       rs542279169       rs542793735       rs542982949       rs543063101       rs543095374       rs543185706       rs543430217       rs543596681       rs543636968       rs543927370       rs543941138       rs544365425       rs544379953       rs544563036       rs544605485       rs544626867       rs544665578       rs544737736       rs544934206       rs545154138       rs545716253       rs545732531       rs545956598       rs545999875       rs546166007       rs546588039       rs546670817       rs546745985       rs546756301       rs546793108       rs546841733       rs546843598       rs546929508       rs547204429       rs547241170       rs547326082       rs547450905       rs547708121       rs547881101       rs548036348       rs548420529       rs548597599       rs549124792       rs549414530       rs549576603       rs549660968       rs550082829       rs550574611       rs550637065       rs550652335       rs550867815       rs551378809       rs551535494       rs551740852       rs551775313       rs551812667       rs551975723       rs552018169       rs552022043       rs552109882       rs552213817       rs552325173       rs552450441       rs552486840       rs552631220       rs552709028       rs553041429       rs553056795       rs553058408       rs553080225       rs553477042       rs553478900       rs553564944       rs553967595       rs554275757       rs554476952       rs554873771       rs555238253       rs555334743       rs555693578       rs555830408       rs555893673       rs556094903       rs556182426       rs556288837       rs556512266       rs556881540       rs557206725       rs557333313       rs557793269       rs558072182       rs558109149       rs558367708       rs558499041       rs558653942       rs558725888       rs558897124       rs559203047       rs559203806       rs559289991       rs559329832       rs559412859       rs559576820       rs559686848       rs559722121       rs560012985       rs560018789       rs560559565       rs560591674       rs560615363       rs560783536       rs561005501       rs561173643       rs561209882       rs561439169       rs561485190       rs561503117       rs561702838       rs561835303       rs561871541       rs562354221       rs562516428       rs562590399       rs562763045       rs563035494       rs563124136       rs563301702       rs563315549       rs563352262       rs563384879       rs563548971       rs564128680       rs564146190       rs564395826       rs564418741       rs564701926       rs564900864       rs564921844       rs564933447       rs565135465       rs565222800       rs565403232       rs565495937       rs565705224       rs565818459       rs566174315       rs566381838       rs566915934       rs566926634       rs566934374       rs567471147       rs567610513       rs567625031       rs567665872       rs567728114       rs568018563       rs568109078       rs568143757       rs568397588       rs568519918       rs568564054       rs568721263       rs568808530       rs569060678       rs569157331       rs569169895       rs569228786       rs569312515       rs569316335       rs569563588       rs569675304       rs569794249       rs569867333       rs570082664       rs570305134       rs570432722       rs570503967       rs570540881       rs570591761       rs571103938       rs571134342       rs571429666       rs571451017       rs571617743       rs571743340       rs571829301       rs572139877       rs572211082       rs572797232       rs573193978       rs573230662       rs573690646       rs573817146       rs574444706       rs574527709       rs574615425       rs575509657       rs575548273       rs575588433       rs575757374       rs575794644       rs575897591       rs575944541       rs576027063       rs576384459       rs576497194       rs576637515       rs576758780       rs576813827       rs576855744       rs576859484       rs577323647       rs577718450       rs577770789       rs577840820       rs578172767       rs745340366       rs745513263       rs745552253       rs745621466       rs745674978       rs745898676       rs745962060       rs746026067       rs746227205       rs746435150       rs746535489       rs746769946       rs746813123       rs746826999       rs747065109       rs747119693       rs747307399       rs747317988       rs747500221       rs747618485       rs747642854       rs748083299       rs748131786       rs748375898       rs748539203       rs748769072       rs748882359       rs748995277       rs749108691       rs749277120       rs749297006       rs749324327       rs749429122       rs749615430       rs749857233       rs749864407       rs749946704       rs749960537       rs750139262       rs750190755       rs750260671       rs750440247       rs750505957       rs750712776       rs750753652       rs751323479       rs751336433       rs751610006       rs751790030       rs751841151       rs751926200       rs752237331       rs752458659       rs752487888       rs753071577       rs753126904       rs753253994       rs753324320       rs753570181       rs753867150       rs753892359       rs753905653       rs754001343       rs754010310       rs754126698       rs754257075       rs754567070       rs754608071       rs754951141       rs754984756       rs755217072       rs755459738       rs755520030       rs755581771       rs755708534       rs755837834       rs756543596       rs756893150       rs756946393       rs757173906       rs757175044       rs757197035       rs757226964       rs757439312       rs757483068       rs757501987       rs757786591       rs758018720       rs758023820       rs758068796       rs758154086       rs758298583       rs758325341       rs758566891       rs758625721       rs758645392       rs758670077       rs758769542       rs758910410       rs758914779       rs759060788       rs759258188       rs759379609       rs759559158       rs759589107       rs759602106       rs759671927       rs759718991       rs759901601       rs760035759       rs760336599       rs760361678       rs760413231       rs760789776       rs760857889       rs760909396       rs760970669       rs761027045       rs761182689       rs761536614       rs761730775       rs761861061       rs761922515       rs762111465       rs762173791       rs762305738       rs762311530       rs762507003       rs762739726       rs762798470       rs762998852       rs763122265       rs763324646       rs763413351       rs763506612       rs763599568       rs763690954       rs763909520       rs764140737       rs764334443       rs764418826       rs764658964       rs765046353       rs765099595       rs765128645       rs765183459       rs765791031       rs765843965       rs765963260       rs766086207       rs766368714       rs766419339       rs766421951       rs766438750       rs766583861       rs766593230       rs767104236       rs767517592       rs767570580       rs767665930       rs767762590       rs767817045       rs767856988       rs768281079       rs768321561       rs768536054       rs768769875       rs769025173       rs769060275       rs769131181       rs769153639       rs769596697       rs769786368       rs770222960       rs770264528       rs770265789       rs770632441       rs770667769       rs770699256       rs770785171       rs770985751       rs771002314       rs771071398       rs771680898       rs771736077       rs772059787       rs772154760       rs772391677       rs772424741       rs772447299       rs772468324       rs772520906       rs772640005       rs772805551       rs773036759       rs773459101       rs773589533       rs773598047       rs773640896       rs774097907       rs774127616       rs774151091       rs774151272       rs774564847       rs774566053       rs774589067       rs774591921       rs774646988       rs774785215       rs775046543       rs775174153       rs775342902       rs775380022       rs775685826       rs775746531       rs775911870       rs775990266       rs776083669       rs776250289       rs776303684       rs776357775       rs776565022       rs776959830       rs777252016       rs777307167       rs777435419       rs777460453       rs777698250       rs777801883       rs777942152       rs778417803       rs778620463       rs778752861       rs778846147       rs779406442       rs779424847       rs779449131       rs779458717       rs779460628       rs779769070       rs779978162       rs780033157       rs780086956       rs780365309       rs780549749       rs780566013       rs780679458       rs780892789       rs781127466       rs781140496       rs781178898       rs781210267       rs781237311       rs781239708      

基因表达

基因表达

WNT10A基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ACACCAATTCAGGGACCAG
59
TGTTCTCCATCACTGCCTC
59
TTCTAAGGACTTTCTGGACTCC
59
TGTTCTCCATCACTGCCTG
59
TTTCTAAGGACTTTCTGGACTCC
59
TGTTCTCCATCACTGCCTG
59
ACACCAATTCAGGGACCAG
59
TTCTCCATCACTGCCTCTG
59
AACACCAATTCAGGGACCA
59
TTCTCCATCACTGCCTCTG
59
TTAAGCTGGTCTCTGAACTC
57
ACACTTTGGGAATTGGAGG
57
AGAGCTCAAGCGATTCTCC
59
GCCTGTAGTCCTGTAGTCC
58
TAGACCGAGTGAATCCAGG
58
AACCTCGAGCTTATTAAACTGC
59
CTAAGGACTTTCTGGACTCCC
59
TGTTCTCCATCACTGCCTG
59
GGGCTCAAGTTATCCTCCC
59
TGGCTCAGTCTCTGTAACC
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

WNT10A基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

WNT10A基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005102
H7BZB8(UniProtKB)
IEA
GO:0005578
H7BZB8(UniProtKB)
IEA
GO:0007275
H7BZB8(UniProtKB)
IEA
GO:0016055
H7BZB8(UniProtKB)
IEA
GO:0001942
Q9GZT5(UniProtKB)
IMP
GO:0001942
Q9GZT5(UniProtKB)
IMP
GO:0005109
Q9GZT5(UniProtKB)
IBA
GO:0005576
Q9GZT5(UniProtKB)
TAS
GO:0005578
Q9GZT5(UniProtKB)
IEA
GO:0005615
Q9GZT5(UniProtKB)
IBA
GO:0010628
Q9GZT5(UniProtKB)
IEA
GO:0014033
Q9GZT5(UniProtKB)
IEA
GO:0016055
Q9GZT5(UniProtKB)
IBA
GO:0016055
Q9GZT5(UniProtKB)
TAS
GO:0030182
Q9GZT5(UniProtKB)
IBA
GO:0031069
Q9GZT5(UniProtKB)
IMP
GO:0042476
Q9GZT5(UniProtKB)
IMP
GO:0042476
Q9GZT5(UniProtKB)
IMP
GO:0042487
Q9GZT5(UniProtKB)
IEA
GO:0043586
Q9GZT5(UniProtKB)
IMP
GO:0043586
Q9GZT5(UniProtKB)
IMP
GO:0043588
Q9GZT5(UniProtKB)
IMP
GO:0043588
Q9GZT5(UniProtKB)
IMP
GO:0045165
Q9GZT5(UniProtKB)
IBA
GO:0048730
Q9GZT5(UniProtKB)
IMP
GO:0048733
Q9GZT5(UniProtKB)
IMP
GO:0071560
Q9GZT5(UniProtKB)
IEP

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控WNT10A基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
SCHOPF-SCHULZ-PASSARGE SYNDROME (disorder) 0.361628651 6 1 BeFree_CLINVAR_CTD_human_ORPHANET
Odontoonychodermal dysplasia 0.36 1 6 CLINVAR_CTD_human_UNIPROT
TOOTH AGENESIS, SELECTIVE, 4 (disorder) 0.24 3 6 CLINVAR_UNIPROT
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 0.12272435 1 0 CTD_human_LHGDN
Odonto-onycho-dermal dysplasia 0.121628651 6 0 BeFree_ORPHANET
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive 0.12 0 0 ORPHANET
Ectodermal Dysplasia 0.005167327 9 0 BeFree_LHGDN
Hypodontia 0.003257302 12 0 BeFree
Malignant neoplasm of stomach 0.000814326 3 0 BeFree
Tooth Loss 0.000814326 3 0 BeFree
Christ-Siemens-Touraine syndrome 0.000814326 3 0 BeFree
Developmental absence of tooth 0.000814326 3 0 BeFree
Stomach Carcinoma 0.000814326 3 0 BeFree
Increased sweating 0.000542884 2 0 BeFree
Anhydrotic Ectodermal Dysplasias 0.000542884 2 0 BeFree
Zlotogora-Ogur syndrome 0.000542884 2 0 BeFree
Congenital Abnormality 0.000271442 1 0 BeFree
Renal Cell Carcinoma 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Cyst 0.000271442 1 0 BeFree
Esophageal Neoplasms 0.000271442 1 0 BeFree
Kidney Diseases 0.000271442 1 0 BeFree
Skin Neoplasms 0.000271442 1 0 BeFree
Acute interstitial nephritis 0.000271442 1 0 BeFree
Renal fibrosis 0.000271442 1 0 BeFree
Esophageal carcinoma 0.000271442 1 0 BeFree
Teratocarcinoma 0.000271442 1 0 BeFree
Congenital anomaly of face 0.000271442 1 0 BeFree
Squamous cell carcinoma of esophagus 0.000271442 1 0 BeFree
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site 0.000271442 1 0 BeFree
Associated symptom 0.000271442 1 0 BeFree
Malignant neoplasm of esophagus 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Tooth Agenesis, Familial 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

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