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Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  蛋白质泛素化控制许多细胞内的过程,包括细胞周期进程,转录激活,和信号转导。这种动态的过程,涉及到泛素结合酶和酶去泛素,添加和删除泛素。去泛素酶是特异性从泛素 - 缀合的蛋白底物切割泛素的半胱氨酸蛋白酶。这种基因编码位于染色体上Xp11.23基因簇一个去泛素化酶[由提供RefSeq的,2008年7月]
USP11基因(以及对应的蛋白质)的细胞分布位置:
USP11基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Disorder of eye | 0.000271442 | 1 | 0 | BeFree |
Fanconi Anemia | 0.000271442 | 1 | 0 | BeFree |
Mental Retardation | 0.000271442 | 1 | 0 | BeFree |
Retinal Diseases | 0.000271442 | 1 | 0 | BeFree |
Retinitis Pigmentosa | 0.000271442 | 1 | 0 | BeFree |
Pancreatic carcinoma | 0.000271442 | 1 | 0 | BeFree |
Night blindness, congenital stationary | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of pancreas | 0.000271442 | 1 | 0 | BeFree |
Pancreatic Ductal Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) | 0.000271442 | 1 | 0 | BeFree |
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