UBE3A基因详情-基因数据库-基因云馆

UBE3A(ubiquitin protein ligase E3A)

基因简称(symbol)

UBE3A [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

AS|ANCR|E6-AP|FLJ26981

基因家族代码(gene_family_id)

[HGNC] [GenScript]

omim代码

601623

entrez码

7337 [Vega]

vega基因码

ensembl基因码

ENSG00000114062 [Ensembl]

基因家族(gene family)

refseq数据库代号

NM_000462

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

15q11.2

同源基因名称(alias name)

Angelman syndrome

基因名称批准使用时间(date_approved_reserved)

1993-10-21T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

2008-07-31T00:00:00Z

更新时间(date_modified)

2015-04-22T00:00:00Z

ucsc码

uc001zas.3

ena

AF002224

ccds数据码

CCDS32177|CCDS45191|CCDS45192

uniprot数据码

Q05086

pubmed代码

8221889

mgd码

MGI:105098

rgd码

RGD:1306361

生命科学数据库(lsdb)

NGRL, Manchester LOVD|http://ngrl.manchester.ac.uk/LOVDv.2.0/home.php?select_db=UBE3A|LRG_15|http://www.lrg-sequence.org/LRG/LRG_15

更新时间(date modified)

2015-04-22T00:00:00Z

cosmic

UBE3A

mirbase

基因曾用简称(prev symbol)

EPVE6AP|HPVE6A

基因曾用名称(prev name)

human papilloma virus E6-associated protein

homeodb

cosmic

UBE3A

snornabase

bioparadigms slc

orphanet

120365

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

6.3.2.19

中间纤维数据库

收起

15q11.2

This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):] 这个基因编码的E3泛素 - 蛋白质连接酶，泛素蛋白降解系统的一部分。此印迹基因在脑母系表达和在其它组织biallelically表达。该基因的母系遗传缺失导致安琪儿综合征，其特点是严重的运动和智力发育迟缓，共济失调，肌张力低下，癫痫，无语音和特点相。蛋白质还与人乳头瘤病毒16型和18的E6蛋白相互作用，导致泛素化和肿瘤蛋白的p53蛋白水解。在三个转录本基因导致选择性剪接变异体编码三种亚型具有不同的N端。额外转录变体进行了说明，但它们的全长性质尚未确定。 [由RefSeq的，2008年7月提供]

OMIM数据库中对UBE3A基因的介绍 Wikipedia数据库中对UBE3A基因的介绍

UBE3A基因的碱基序列：[NCBI]

UBE3A基因的碱基突变：显示全部snp

rs732739 rs734127 rs734238 rs757438 rs1041933 rs1059383 rs1063209 rs1116423 rs1557832 rs1557872 rs1557873 rs1557874 rs1859359 rs2066728 rs2107455 rs2158305 rs2158306 rs2248498 rs2257252 rs2283428 rs2340625 rs2524357 rs2526025 rs2526026 rs2719878 rs2719880 rs2719881 rs2719924 rs2839719 rs3043907 rs3220254 rs3784766 rs3887213 rs4012491 rs4445877 rs4467052 rs4488416

rs4906710 rs4906711 rs5811380 rs5811381 rs6420957 rs6420958 rs6576419 rs6576421 rs6576422 rs6576423 rs7163944 rs7164510 rs7165149 rs7165929 rs7166201 rs7166361 rs7166686 rs7167529 rs7170449 rs7171350 rs7173786 rs7175021 rs7175559 rs7175773 rs7175968 rs7176461 rs7176973 rs7178181 rs7181129 rs7182619 rs7182827 rs7402857 rs7495556 rs7495632 rs7496494 rs7496951 rs8023329 rs8024413 rs8024421 rs8024771 rs8024975 rs8025093 rs8025215 rs8025830 rs8026555 rs8026998 rs8028635 rs8028644 rs8029139 rs8030988 rs8031756 rs8032479 rs8035415 rs8036658 rs8038173 rs8039641 rs8040809 rs8042058 rs8042126 rs8042829 rs8179187 rs8192277 rs9806741 rs9806751 rs9944204 rs10047992 rs10162640 rs10162711 rs10162747 rs10162768 rs10162823 rs10163104 rs10519485 rs10519489 rs10713541 rs11161173 rs11161174 rs11161175 rs11161176 rs11161177 rs11302221 rs11321524 rs11396663 rs11413336 rs11421203 rs11438354 rs11631038 rs11633072 rs11852730 rs11853408 rs11853692 rs11854361 rs11855196 rs11855777 rs11856839 rs11857412 rs11858341 rs11858841 rs12148726 rs12438385 rs12439344 rs12440229 rs12443207 rs12591773 rs12592517 rs12592675 rs12593501 rs12595544 rs12717754 rs12899183 rs12899575 rs12899780 rs12899875 rs12901086 rs12901934 rs12903288 rs12903964 rs12904031 rs12904041 rs12904063 rs12905879 rs12906449 rs12906457 rs12907375 rs12907464 rs12909666 rs12910230 rs12910441 rs12910695 rs12910781 rs12914201 rs12915195 rs12917607 rs13380005 rs17114442 rs17115482 rs17115485 rs17115494 rs17115502 rs17115520 rs17115526 rs17115527 rs17115567 rs17115577 rs17115585 rs28379525 rs28386973 rs28397621 rs28398938 rs28445953 rs28496222 rs28528079 rs28536157 rs28595505 rs28615091 rs28623489 rs28658030 rs28754450 rs28758239 rs28798996 rs28808105 rs28818468 rs28862383 rs34020669 rs34050354 rs34051514 rs34212558 rs34285975 rs34305718 rs34428856 rs34498753 rs34501187 rs34610959 rs34630366 rs34662118 rs34670662 rs34698527 rs34825571 rs35030552 rs35086186 rs35126146 rs35253090 rs35327656 rs35386735 rs35410912 rs35481420 rs35534759 rs35654404 rs35793437 rs35861025 rs36057934 rs36117412 rs55817493 rs55818615 rs55893421 rs55928350 rs56192245 rs56329860 rs56786510 rs57025744 rs57111857 rs57348357 rs57478621 rs57503424 rs57524621 rs57720638 rs58419206 rs58585994 rs59229274 rs59393456 rs59539868 rs59779980 rs59931652 rs60024090 rs60468744 rs60511546 rs60658008 rs61336305 rs61396551 rs61482373 rs61696971 rs61734190 rs61740969 rs61740972 rs61998983 rs61998987 rs61998988 rs61998989 rs61998990 rs61998993 rs61998994 rs61998996 rs66603513 rs66607547 rs66937842 rs66955274 rs67234848 rs67313247 rs67785909 rs67982355 rs71127050 rs71127051 rs71127052 rs71127053 rs71127055 rs71127057 rs71127058 rs71127060 rs71127062 rs71395087 rs71418038 rs71418039 rs71418040 rs71418041 rs71418043 rs71418044 rs71418045 rs71463452 rs71463453 rs71463454 rs71463455 rs71912794 rs72697776 rs72697784 rs72697785 rs72697787 rs72697789 rs72697793 rs72697799 rs73364194 rs73364197 rs73364198 rs73366212 rs73366217 rs73366220 rs73366230 rs73366244 rs73366253 rs73366262 rs73366276 rs73366287 rs73366290 rs74006409 rs74006411 rs74006412 rs74006413 rs74006414 rs74006415 rs74337129 rs74377376 rs74442322 rs74474835 rs74571008 rs74609474 rs74946267 rs75004194 rs75076484 rs75115998 rs75126022 rs75143971 rs75154153 rs75166723 rs75309989 rs75311514 rs75491587 rs75605946 rs75606291 rs75607162 rs75722102 rs75804557 rs75806084 rs75809595 rs75809831 rs76008012 rs76050904 rs76056788 rs76319509 rs76369560 rs76396390 rs76426459 rs76521264 rs76601439 rs76790209 rs76790710 rs76794400 rs76808002 rs76925282 rs76938976 rs76944426 rs76954187 rs77056135 rs77156062 rs77185739 rs77218458 rs77291133 rs77329250 rs77341861 rs77383502 rs77387634 rs77394984 rs77452697 rs77550689 rs77631699 rs77699256 rs77764328 rs77798821 rs78080621 rs78143724 rs78177126 rs78277208 rs78322622 rs78336119 rs78338561 rs78368543 rs78424642 rs78446449 rs78495679 rs78584605 rs78680551 rs78728859 rs78781506 rs78872891 rs78873369 rs78877629 rs78964954 rs79014457 rs79032599 rs79328837 rs79397968 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rs138653426 rs138678451 rs138689280 rs138710474 rs138721740 rs138798844 rs138917977 rs138997541 rs139023620 rs139082033 rs139087621 rs139121108 rs139125448 rs139190663 rs139212904 rs139213974 rs139214824 rs139261042 rs139315949 rs139346200 rs139373427 rs139383749 rs139441275 rs139487198 rs139548123 rs139566047 rs139658177 rs139674819 rs139791291 rs139820969 rs139829756 rs139871841 rs139878808 rs139897415 rs139912001 rs139928148 rs139988659 rs140042000 rs140088899 rs140105437 rs140127746 rs140206537 rs140217995 rs140228271 rs140230447 rs140245963 rs140248616 rs140252517 rs140335344 rs140363545 rs140411031 rs140502424 rs140605906 rs140623759 rs140632097 rs140668593 rs140672992 rs140718817 rs140724246 rs140789991 rs140796320 rs140847728 rs140923368 rs140973167 rs141038559 rs141040982 rs141108332 rs141122959 rs141136772 rs141142478 rs141148624 rs141208261 rs141244885 rs141331810 rs141370451 rs141429266 rs141432438 rs141469877 rs141491196 rs141509962 rs141561643 rs141582146 rs141613220 rs141656539 rs141684940 rs141723551 rs141738295 rs141780664 rs141872434 rs141879201 rs141895268 rs141935390 rs141945138 rs141974254 rs141979440 rs141984760 rs142025753 rs142064929 rs142099921 rs142135993 rs142138490 rs142138895 rs142163706 rs142168555 rs142194249 rs142216821 rs142392819 rs142396219 rs142408011 rs142452750 rs142458037 rs142536177 rs142537023 rs142547822 rs142556992 rs142566235 rs142595289 rs142603974 rs142637718 rs142726511 rs142737382 rs142758020 rs142782577 rs142932378 rs142978288 rs143000400 rs143023395 rs143038137 rs143071638 rs143113218 rs143167958 rs143180745 rs143184864 rs143205986 rs143224622 rs143303152 rs143309725 rs143310195 rs143351421 rs143358367 rs143394184 rs143453261 rs143484751 rs143525914 rs143617675 rs143626834 rs143647688 rs143704350 rs143726696 rs143776481 rs143813890 rs143895884 rs144020219 rs144025596 rs144046872 rs144052366 rs144068356 rs144139580 rs144234771 rs144241676 rs144337281 rs144391638 rs144427729 rs144473671 rs144485793 rs144492381 rs144548866 rs144567527 rs144595797 rs144646946 rs144684368 rs144690194 rs144748566 rs144781671 rs144833404 rs144836008 rs144853855 rs144875976 rs144909782 rs144950303 rs144963402 rs145005854 rs145007154 rs145072298 rs145140525 rs145188076 rs145223565 rs145245864 rs145252457 rs145272931 rs145318009 rs145320182 rs145338862 rs145357886 rs145397441 rs145443289 rs145514960 rs145546450 rs145607839 rs145645787 rs145669535 rs145748652 rs145796537 rs145796960 rs145824911 rs145857683 rs145892509 rs145906443 rs145916848 rs145980196 rs145989715 rs146001342 rs146028198 rs146090553 rs146109515 rs146128675 rs146129250 rs146141111 rs146211550 rs146222947 rs146225216 rs146343954 rs146350677 rs146351558 rs146408800 rs146424190 rs146435869 rs146450619 rs146473582 rs146536851 rs146611520 rs146613335 rs146657743 rs146658023 rs146667643 rs146693575 rs146704831 rs146771574 rs146815289 rs146955518 rs146965593 rs146987919 rs146997852 rs147036976 rs147058479 rs147069704 rs147145506 rs147218829 rs147235507 rs147246886 rs147335234 rs147343596 rs147353683 rs147446244 rs147502917 rs147544796 rs147545258 rs147608127 rs147618258 rs147641016 rs147672223 rs147744911 rs147816897 rs147826459 rs147834548 rs147844523 rs147931980 rs147932302 rs147955391 rs148021119 rs148118528 rs148128057 rs148151724 rs148171142 rs148180838 rs148279548 rs148310230 rs148319786 rs148320647 rs148361336 rs148415998 rs148429904 rs148467824 rs148506064 rs148526028 rs148557880 rs148581241 rs148613018 rs148619093 rs148642587 rs148670943 rs148706080 rs148771091 rs148802048 rs148822911 rs148832800 rs148908848 rs148960055 rs148971151 rs149095754 rs149155126 rs149167912 rs149201349 rs149294808 rs149325880 rs149350115 rs149434083 rs149486201 rs149506027 rs149508889 rs149527247 rs149541253 rs149559304 rs149650803 rs149662890 rs149757948 rs149786356 rs149789260 rs149810242 rs149824737 rs149845003 rs149854051 rs149873542 rs149970079 rs150020186 rs150031827 rs150051585 rs150102608 rs150103240 rs150123386 rs150144351 rs150154416 rs150179820 rs150199256 rs150214122 rs150258468 rs150302822 rs150312862 rs150331504 rs150355916 rs150356473 rs150406321 rs150496280 rs150500621 rs150597341 rs150647778 rs150669265 rs150689521 rs150692128 rs150721994 rs150795382 rs150840095 rs150850953 rs150879631 rs150902863 rs150952046 rs150991995 rs150994959 rs151007637 rs151027998 rs151048707 rs151072121 rs151111363 rs151163822 rs151186013 rs151195647 rs151216650 rs180732456 rs180750571 rs180751597 rs180762937 rs180764564 rs180766184 rs180770137 rs180792773 rs180817355 rs180998103 rs181000823 rs181003902 rs181007927 rs181023783 rs181023922 rs181029718 rs181041417 rs181060308 rs181204225 rs181222277 rs181227276 rs181234778 rs181299194 rs181375992 rs181408330 rs181410848 rs181453067 rs181528468 rs181617140 rs181672139 rs181725665 rs181725780 rs181735947 rs181859258 rs181930545 rs181931958 rs181950496 rs181953714 rs182074601 rs182080366 rs182082698 rs182106790 rs182133566 rs182165744 rs182382955 rs182387648 rs182402260 rs182407271 rs182417185 rs182421166 rs182421497 rs182425044 rs182428294 rs182437085 rs182639592 rs182644050 rs182667654 rs182667841 rs182678474 rs182757044 rs182778313 rs182796980 rs182931466 rs182956957 rs182986494 rs182987891 rs183009241 rs183011465 rs183024378 rs183226755 rs183234873 rs183251047 rs183273321 rs183275104 rs183292058 rs183455562 rs183481264 rs183495266 rs183495459 rs183519445 rs183538802 rs183573179 rs183579749 rs183663175 rs183686799 rs183690009 rs183703668 rs183798710 rs183801624 rs183851817 rs183905650 rs183920433 rs183923138 rs183960618 rs184065527 rs184127351 rs184169544 rs184265860 rs184345154 rs184349133 rs184352640 rs184370245 rs184381136 rs184405137 rs184591700 rs184617947 rs184621992 rs184660688 rs184674979 rs184702344 rs184705377 rs184706002 rs184766593 rs184846224 rs184850478 rs184958207 rs184986333 rs185014805 rs185092741 rs185105069 rs185154184 rs185172864 rs185254524 rs185344027 rs185354916 rs185377987 rs185386196 rs185403859 rs185415805 rs185496480 rs185520049 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rs188461004 rs188620110 rs188632630 rs188643082 rs188664521 rs188665032 rs188678260 rs188688206 rs188805921 rs188807954 rs188918764 rs188939470 rs189053153 rs189055261 rs189059478 rs189075740 rs189135296 rs189171110 rs189184544 rs189218759 rs189256829 rs189303435 rs189319235 rs189333326 rs189407120 rs189416104 rs189438125 rs189438528 rs189553938 rs189694489 rs189700116 rs189778283 rs189782611 rs189805427 rs189805504 rs189820221 rs189938714 rs189951560 rs189951732 rs189972013 rs189993872 rs189996913 rs190016483 rs190025386 rs190033157 rs190064748 rs190183524 rs190186052 rs190225242 rs190230605 rs190265206 rs190309479 rs190426373 rs190463474 rs190470892 rs190470959 rs190496135 rs190531144 rs190715373 rs190719912 rs190771538 rs190781945 rs191009427 rs191110789 rs191147162 rs191151619 rs191187248 rs191189196 rs191197495 rs191229199 rs191237912 rs191240898 rs191263303 rs191494545 rs191512741 rs191516924 rs191522978 rs191621026 rs191622658 rs191625936 rs191788567 rs191794031 rs191811083 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rs576366026 rs576393126 rs576499731 rs576531877 rs576558384 rs576600148 rs576611366 rs576637494 rs576689005 rs576703042 rs576789818 rs576835543 rs576873057 rs576881212 rs576904840 rs576936330 rs576960375 rs576963061 rs577006098 rs577024634 rs577050459 rs577085383 rs577103806 rs577109456 rs577110713 rs577121851 rs577163735 rs577192268 rs577290190 rs577294145 rs577310942 rs577319182 rs577333268 rs577440472 rs577455093 rs577461404 rs577500690 rs577527065 rs577569938 rs577685596 rs577733574 rs577733676 rs577796670 rs577857584 rs577873160 rs577879410 rs577904127 rs577976715 rs577985555 rs577998606 rs578013810 rs578123839 rs578127828 rs578140539 rs578187139 rs578187412 rs578189723 rs578212184 rs578219318 rs578247746 rs587780991 rs587781236 rs587782910 rs587782914 rs587782916 rs587782917 rs587782923 rs587782925 rs587783098 rs587783099 rs587783100 rs587783101 rs587783102 rs587783103 rs587783146 rs587783147 rs587783148 rs587784511 rs745340054 rs745363984 rs745427746 rs745439205 rs745457864 rs745680579 rs745758976 rs746005526 rs746027742 rs746196529 rs746286431 rs746471374 rs746497969 rs746767378 rs746769407 rs746859435 rs746907249 rs747036762 rs747068246 rs747178974 rs747228754 rs747336961 rs747494501 rs747499662 rs747626553 rs747721530 rs747774450 rs747932207 rs748038950 rs748261720 rs748350055 rs748426530 rs748545856 rs748572808 rs748580495 rs748608117 rs748803444 rs748909714 rs749037536 rs749059176 rs749178181 rs749256976 rs749384749 rs749532215 rs749643187 rs749643307 rs749731066 rs750036329 rs750079351 rs750237106 rs750472782 rs750562112 rs750926219 rs751001423 rs751134662 rs751370485 rs751449644 rs751477028 rs751573656 rs751766501 rs751838524 rs752005918 rs752006820 rs752281883 rs752310016 rs752633417 rs752710527 rs752711811 rs752810430 rs753068193 rs753078220 rs753187955 rs753277802 rs753429030 rs753519257 rs753643576 rs753682159 rs753919582 rs753920397 rs753988917 rs754336508 rs754387676 rs754422753 rs754504668 rs754664908 rs754810910 rs755003820 rs755078197 rs755098625 rs755226524 rs755392575 rs755413041 rs755506955 rs755579490 rs755581358 rs755765955 rs755809720 rs755878219 rs755929654 rs756024206 rs756035767 rs756148540 rs756184438 rs756202981 rs756203040 rs756292607 rs756481618 rs756688745 rs756710925 rs756899000 rs757072130 rs757224979 rs757351048 rs757375214 rs757512212 rs757540819 rs757550208 rs757842734 rs757862878 rs757922956 rs757993646 rs758077036 rs758306494 rs758534647 rs758685056 rs758694652 rs758845426 rs758932084 rs759095902 rs759153831 rs759225128 rs759311003 rs759312941 rs759333023 rs759506531 rs759545530 rs759637167 rs759922228 rs759994828 rs759997935 rs760247849 rs760266324 rs760283316 rs760354074 rs760397761 rs760455366 rs760473859 rs760573646 rs760844102 rs761011538 rs761028002 rs761085385 rs761115114 rs761344289 rs761394184 rs761484197 rs761529762 rs761985921 rs761991255 rs762051839 rs762154663 rs762172890 rs762247869 rs762475902 rs762637018 rs763025705 rs763097042 rs763113625 rs763388142 rs763466104 rs763813429 rs764057476 rs764101035 rs764195093 rs764196816 rs764213267 rs764318379 rs764366280 rs764419235 rs764773970 rs764956642 rs765065450 rs765089240 rs765466719 rs765490692 rs765727905 rs765813410 rs765910610 rs766111654 rs766144091 rs766288688 rs766390290 rs766474336 rs766597966 rs766668640 rs766973981 rs767063794 rs767254317 rs767297415 rs767330376 rs767416040 rs767551803 rs767674409 rs767720713 rs767815586 rs767903684 rs768273106 rs768326089 rs768431851 rs768524039 rs768685465 rs769052255 rs769103004 rs769119425 rs769284300 rs769372364 rs769556539 rs769608138 rs769775137 rs770063345 rs770078054 rs770109659 rs770131629 rs770199759 rs770288588 rs770594226 rs770757909 rs770845702 rs770913416 rs770936366 rs771122519 rs771316176 rs771390878 rs771689734 rs771697024 rs771812460 rs771906220 rs771985048 rs772071204 rs772110423 rs772130716 rs772621378 rs772621825 rs772771724 rs772952625 rs773112531 rs773350583 rs773378507 rs773438461 rs773522328 rs773701872 rs773718237 rs773872971 rs773890941 rs774057617 rs774072376 rs774138623 rs774239596 rs774363647 rs774533700 rs774594429 rs774618110 rs774629852 rs774704374 rs774826100 rs774837716 rs774856117 rs774940541 rs775070175 rs775146178 rs775397987 rs775589140 rs775732231 rs775778774 rs776045188 rs776127040 rs776294550 rs776323812 rs776411035 rs776458837 rs776544230 rs776564692 rs776735747 rs776739000 rs776844684 rs776898798 rs776900987 rs777237357 rs777538399 rs777672019 rs777786077 rs777833440 rs777844690 rs777868954 rs777914428 rs778060771 rs778148779 rs778264299 rs778354090 rs778513573 rs778608390 rs778703338 rs778808533 rs778892960 rs778909379 rs778994586 rs779206432 rs779375881 rs779502970 rs779575880 rs779617836 rs779664745 rs779671805 rs779737496 rs779742078 rs779846117 rs779980643 rs780050034 rs780063328 rs780225783 rs780429591 rs780440418 rs780715298 rs780996570 rs781090400 rs781104195 rs781163963 rs781176867 rs781211197 rs781249210 rs781537729 rs781544724 rs781556374 rs868403043 rs869085037 rs869210765 rs869258751

UBE3A基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

GAAGCTAGCCGAATGAAGC

59

TTAACTGGTGGTAGTAGCGT

58

ATTTAGCCGTGTGCTTGAG

58

TGGTAGGGATCATCTCTTCCA

59

TCTGATTAGGGAGTTCTGGGA

59

CTGTGCCCGTTGTAAACTG

59

GAAGCTAGCCGAATGAAGC

59

GTTAACTGGTGGTAGTAGCG

58

GAAGCTAGCCGAATGAAGC

59

TCATTTCCACAGCCCTCAG

59

GAGTTATTAAGCCTACGCTCAG

58

CATTCGGTGACATCAGGGT

59

GACTCTGTTCTGATTAGGGAG

57

GTTGTAAACTGCAAGAAGAGTC

58

TATTTAGCCGTGTGCTTGAG

58

GGTAGGGATCATCTCTTCCA

58

GAAGCTAGCCGAATGAAGC

59

CAGGCTTCATTTCCACAGC

59

TGAGTTATTAAGCCTACGCTC

57

CTTGCTCCTTTATTCGGCT

57

尚未收录相关数据

UBE3A基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

UBE3A基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0004842

A0A0D9SG63(UniProtKB)

IEA

GO:0016567

A0A0D9SG63(UniProtKB)

IEA

GO:0016874

A0A0D9SG63(UniProtKB)

IEA

GO:0004842

A0A0D9SG77(UniProtKB)

IEA

GO:0016567

A0A0D9SG77(UniProtKB)

IEA

GO:0016874

A0A0D9SG77(UniProtKB)

IEA

GO:0000502

Q05086(UniProtKB)

IEA

GO:0001541

Q05086(UniProtKB)

IEA

GO:0003713

Q05086(UniProtKB)

IEA

GO:0004842

Q05086(UniProtKB)

IDA

GO:0004842

Q05086(UniProtKB)

IDA

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005515

Q05086(UniProtKB)

IPI

GO:0005634

Q05086(UniProtKB)

IBA

GO:0005737

Q05086(UniProtKB)

IBA

GO:0005829

Q05086(UniProtKB)

IEA

GO:0006508

Q05086(UniProtKB)

TAS

GO:0006511

Q05086(UniProtKB)

IEA

GO:0007420

Q05086(UniProtKB)

TAS

GO:0014068

Q05086(UniProtKB)

IEA

GO:0016032

Q05086(UniProtKB)

IEA

GO:0016874

Q05086(UniProtKB)

IEA

GO:0030521

Q05086(UniProtKB)

IBA

GO:0031398

Q05086(UniProtKB)

IDA

GO:0035037

Q05086(UniProtKB)

IEA

GO:0042752

Q05086(UniProtKB)

IMP

GO:0045944

Q05086(UniProtKB)

IEA

GO:0046872

Q05086(UniProtKB)

IEA

GO:0051865

Q05086(UniProtKB)

IDA

GO:0060736

Q05086(UniProtKB)

IEA

GO:0061630

Q05086(UniProtKB)

IMP

GO:0070936

Q05086(UniProtKB)

IDA

GO:2000058

Q05086(UniProtKB)

IMP

GO:0004842

S4R306(UniProtKB)

IEA

GO:0016567

S4R306(UniProtKB)

IEA

GO:0016874

S4R306(UniProtKB)

IEA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控UBE3A基因的相关microRNA：

hsa-miR-24 hsa-miR-375

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Angelman Syndrome	0.366118831	114	112	BeFree_CLINVAR_CTD_human_GAD_LHGDN_MGD
Autistic Disorder	0.132182547	13	0	BeFree_CTD_human_GAD
Epilepsy	0.121628651	7	0	BeFree_CTD_human
Craniofacial Abnormalities	0.12	1	0	CTD_human
Prader-Willi Syndrome	0.005971721	22	0	BeFree
Tuberculosis	0.005362824	2	0	BeFree_GAD_LHGDN
Mammary Neoplasms	0.003267234	3	0	BeFree_LHGDN
Infection	0.00272435	1	0	LHGDN
Cardiomegaly	0.002367032	1	1	GAD
Malignant tumor of cervix	0.001628651	6	0	BeFree
Cervix carcinoma	0.001628651	6	0	BeFree
Carcinogenesis	0.001357209	5	0	BeFree
Neurodevelopmental Disorders	0.001357209	5	0	BeFree
Malignant neoplasm of breast	0.001085767	4	0	BeFree
nervous system disorder	0.001085767	4	0	BeFree
Breast Carcinoma	0.001085767	4	0	BeFree
Autism Spectrum Disorders	0.001085767	4	0	BeFree
Rett Syndrome	0.000814326	3	0	BeFree
Atrial Septal Defects	0.000542884	2	0	BeFree
Mental Retardation	0.000542884	2	0	BeFree
Ataxia	0.000271442	1	0	BeFree
Absence Epilepsy	0.000271442	1	0	BeFree
Failure to Thrive	0.000271442	1	0	BeFree
Huntington Disease	0.000271442	1	0	BeFree
Leukemia, Myelocytic, Acute	0.000271442	1	0	BeFree
Myeloid Leukemia	0.000271442	1	0	BeFree
Muscle hypotonia	0.000271442	1	0	BeFree
Papilloma	0.000271442	1	0	BeFree
Severe mental retardation (I.Q. 20-34)	0.000271442	1	0	BeFree
Hypopigmentation disorder	0.000271442	1	0	BeFree
Tumor Progression	0.000271442	1	0	BeFree
Alkalemia	0.000271442	1	0	BeFree
Trembling	0.000271442	1	0	BeFree
High-Grade Squamous Intraepithelial Lesions	0.000271442	1	0	BeFree
Developmental delay (disorder)	0.000271442	1	0	BeFree
Fragile X chromosome	0.000271442	1	0	BeFree
Neurodegenerative Disorders	0.000271442	1	0	BeFree
invasive cancer	0.000271442	1	0	BeFree
cerebellar function	0.000271442	1	0	BeFree
Chromosome 15q, trisomy	0.000271442	1	0	BeFree
Low Grade Squamous Intraepithelial Neoplasia	0.000271442	1	0	BeFree
Mammary Tumorigenesis	0.000271442	1	0	BeFree
Mowat-Wilson syndrome	0.000271442	1	0	BeFree
ALBINOIDISM, OCULOCUTANEOUS, AUTOSOMAL DOMINANT	0.000271442	1	0	BeFree
Cerebral cortex myoclonus	0.000271442	1	0	BeFree