TUBB2B基因详情-基因数据库-基因云馆

TUBB2B(tubulin, beta 2B class IIb) 转至新版数据库

基因简称(symbol)

TUBB2B [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

MGC8685|DKFZp566F223|bA506K6.1

基因家族代码(gene_family_id)

778 [HGNC] [GenScript]

omim代码

612850

entrez码

347733 [Vega]

vega基因码

OTTHUMG00000014143

ensembl基因码

ENSG00000137285 [Ensembl]

基因家族(gene family)

Tubulins

refseq数据库代号

NM_178012

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

06p25.2

同源基因名称(alias name)

class IIb beta-tubulin

基因名称批准使用时间(date_approved_reserved)

2005-11-03T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

2011-10-10T00:00:00Z

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc003mvg.3

ena

BC001352

ccds数据码

CCDS4485

uniprot数据码

Q9BVA1

pubmed代码

8619474|9110174

mgd码

MGI:1920960

rgd码

RGD:1309427

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

TUBB2B

mirbase

基因曾用简称(prev symbol)

基因曾用名称(prev name)

tubulin, beta 2B

homeodb

cosmic

TUBB2B

snornabase

bioparadigms slc

orphanet

201538

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

6p25.2

The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010]

[中文简述(自动翻译):] 由该基因编码的蛋白质是微管蛋白的beta同种型，其结合GTP和是微管的主要组成部分。这种基因是高度相似TUBB2A和TUBB2C。在这个基因的缺陷是不对称多小脑的起因。 [由RefSeq的，2010年3月提供]

OMIM数据库中对TUBB2B基因的介绍 Wikipedia数据库中对TUBB2B基因的介绍

TUBB2B基因的碱基序列：[NCBI]

TUBB2B基因的碱基突变：显示全部snp

rs2259136 rs2807692 rs2808004 rs4145035 rs4358669 rs4358670 rs4598127 rs7740427 rs7740759 rs7747852 rs7748598 rs7753470 rs7760583 rs7761898 rs7772006 rs7774555 rs7774831 rs9328146 rs9503469 rs9503470 rs9503471 rs9503472 rs9503473 rs9503474 rs9503475 rs9503476 rs9503477 rs10553445 rs10597566 rs11418530 rs11550267 rs13217575 rs17145779 rs28408581 rs41300841 rs73349464 rs73349465

rs74412822 rs75275960 rs76628109 rs77080864 rs78466513 rs78843164 rs79564047 rs80009086 rs111498229 rs111690866 rs111726475 rs111970943 rs112387250 rs112534440 rs112543640 rs112713563 rs112714520 rs112876039 rs112924320 rs113199444 rs113532141 rs114102158 rs114352665 rs114449320 rs115149625 rs115172416 rs115740007 rs115840000 rs115913473 rs116615975 rs116805028 rs117433378 rs117622484 rs138470020 rs138480276 rs139252968 rs141251993 rs141271253 rs141399008 rs141781106 rs142077596 rs144147671 rs144280395 rs144553817 rs145058272 rs146256266 rs146544321 rs146956825 rs147097336 rs147313627 rs148845481 rs149039588 rs150388846 rs150818836 rs151139175 rs181389597 rs181458992 rs182049607 rs182470182 rs182605730 rs182610115 rs183476734 rs184091427 rs184673941 rs185503976 rs185618266 rs186217670 rs186880998 rs187182232 rs187475255 rs187578738 rs188370150 rs188893897 rs189143271 rs189167125 rs189623022 rs190262292 rs190540577 rs191967750 rs192338923 rs192492651 rs193294501 rs199547345 rs200288350 rs200624566 rs201078014 rs201548947 rs201922441 rs202182484 rs367644644 rs367839939 rs368205081 rs368213385 rs368896748 rs369774935 rs370077929 rs370337049 rs371848320 rs371871394 rs371966145 rs372442487 rs372449799 rs372922489 rs373049059 rs373510707 rs373918739 rs374322756 rs374686154 rs374712202 rs375381318 rs375697664 rs377613710 rs397817221 rs398000197 rs527769926 rs528705035 rs528743674 rs529331187 rs529548491 rs529564025 rs529721446 rs529819385 rs531087976 rs531246653 rs531636483 rs531717913 rs531798705 rs532194185 rs532231816 rs532380752 rs533241907 rs533405235 rs533412346 rs533450441 rs533460796 rs533783442 rs534350802 rs534502833 rs535644934 rs535682639 rs536113375 rs536291713 rs537208040 rs538073450 rs538945316 rs539275160 rs539397170 rs539671894 rs540090499 rs540865605 rs540887429 rs541495392 rs541880297 rs541886209 rs542645427 rs542876026 rs542877038 rs542972104 rs543657153 rs543816736 rs543852439 rs544071169 rs544533430 rs544823628 rs546027859 rs546642195 rs546677196 rs547826306 rs548118892 rs548141581 rs548165251 rs548245811 rs549108190 rs549923874 rs550006831 rs550127944 rs550128762 rs550159293 rs550491253 rs551497284 rs551658192 rs551700418 rs552168232 rs552183116 rs552257459 rs552949530 rs553090673 rs553343067 rs554453555 rs554544754 rs555090059 rs555704916 rs556029365 rs556701140 rs556702087 rs556890470 rs557266424 rs557299412 rs557474365 rs558280228 rs558664274 rs558914926 rs558936370 rs560636106 rs561298015 rs561540932 rs561675700 rs562511218 rs563349041 rs563472227 rs563673159 rs564031242 rs564044960 rs564069630 rs564477645 rs564616097 rs566428342 rs566563262 rs567240078 rs568112120 rs569057286 rs569168359 rs571119532 rs571749583 rs572391859 rs572858940 rs573033347 rs573534407 rs573817341 rs573866231 rs573960580 rs574006348 rs574093081 rs575356608 rs575916557 rs576065962 rs576071775 rs577317841 rs577527246 rs577913578 rs578023534 rs578050214 rs587784499 rs587784500 rs745447032 rs745768362 rs745796434 rs746543959 rs746638461 rs746867626 rs746904139 rs747151187 rs747258930 rs747999663 rs748297107 rs748385221 rs748640211 rs748894707 rs748918104 rs749112405 rs749197646 rs750038494 rs750457664 rs750592908 rs750978903 rs751071450 rs751110580 rs751688088 rs751743160 rs751859856 rs751997675 rs752239766 rs752292801 rs752640088 rs752691436 rs753095741 rs753616004 rs754249525 rs754991775 rs755152721 rs755315321 rs755868786 rs756024033 rs756321302 rs757125933 rs757438360 rs757831981 rs757885281 rs758017653 rs758448543 rs758458177 rs758580559 rs758623480 rs758967831 rs759430414 rs759751582 rs759865515 rs760627871 rs760721832 rs761148140 rs761197642 rs761718524 rs761771602 rs762224168 rs762232849 rs763219213 rs763297859 rs763337693 rs763648589 rs763701755 rs764355651 rs765021378 rs765200907 rs765535722 rs765818273 rs766014771 rs766214058 rs766436786 rs766752015 rs766978466 rs767264363 rs767477213 rs767825383 rs767877090 rs768464369 rs768579760 rs768845202 rs769136873 rs769330039 rs769803437 rs770156166 rs770430326 rs770537909 rs770937145 rs771268780 rs771506098 rs771951622 rs772408284 rs772459527 rs772860060 rs772990165 rs773080107 rs773472245 rs773599315 rs773869730 rs774009839 rs774281321 rs774644919 rs774858296 rs774873878 rs775214937 rs775446890 rs775995319 rs776278875 rs776330382 rs776795179 rs776974023 rs777066122 rs777456322 rs777598117 rs777864929 rs778205639 rs778362538 rs778593301 rs778850104 rs778888455 rs779387743 rs779519065 rs779570614 rs779620048 rs779963973 rs780003494 rs780259378 rs780781212 rs781103247 rs781116976 rs781348234 rs781453680 rs869077322

TUBB2B基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

GCAGTTACCATGGAGACAG

58

GAACATATTTGTTACCAGTGGC

58

CCTTACTGAGGAACAAAGGT

57

GGAACATATTTGTTACCAGTGG

58

CCTTACTGAGGAACAAAGGT

57

GAACATATTTGTTACCAGTGGC

58

GCAGTTACCATGGAGACAG

58

GGAACATATTTGTTACCAGTGG

58

GCAGTTACCATGGAGACAG

58

GAACATATTTGTTACCAGTGGC

58

CCTTACTGAGGAACAAAGGT

57

CGAGGAACATATTTGTTACCAG

57

GCAGTTACCATGGAGACAG

58

GGAACATATTTGTTACCAGTGG

58

CAGTTACCATGGAGACAGTG

58

GGAACATATTTGTTACCAGTGG

58

CAGTTACCATGGAGACAGTG

58

GGAACATATTTGTTACCAGTGG

58

尚未收录相关数据

TUBB2B基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

TUBB2B基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0001764

Q9BVA1(UniProtKB)

IMP

GO:0003924

Q9BVA1(UniProtKB)

IEA

GO:0005200

Q9BVA1(UniProtKB)

IEA

GO:0005515

Q9BVA1(UniProtKB)

IPI

GO:0005525

Q9BVA1(UniProtKB)

IEA

GO:0005634

Q9BVA1(UniProtKB)

IDA

GO:0005737

Q9BVA1(UniProtKB)

IEA

GO:0005874

Q9BVA1(UniProtKB)

IDA

GO:0007017

Q9BVA1(UniProtKB)

IEA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控TUBB2B基因的相关microRNA：

hsa-miR-1 hsa-miR-124 hsa-miR-186 hsa-miR-615-3p hsa-miR-877 hsa-miR-92a

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
POLYMICROGYRIA, SYMMETRIC OR ASYMMETRIC	0.44	1	0	CTD_human_MGD_ORPHANET_UNIPROT
Malformations of Cortical Development	0.120542884	3	0	BeFree_CTD_human
Animal Mammary Neoplasms	0.12	1	0	CTD_human
Mammary Neoplasms, Experimental	0.12	1	0	CTD_human
Polymicrogyria, Asymmetric	0.12	0	10	CLINVAR
Schizophrenia	0.00272435	1	0	LHGDN
Mammary Neoplasms	0.00272435	1	0	LHGDN
Polymicrogyria	0.001628651	6	0	BeFree
Congenital Abnormality	0.000542884	2	0	BeFree
Microcephaly	0.000542884	2	0	BeFree
Ocular Motility Disorders	0.000271442	1	0	BeFree
Scoliosis, unspecified	0.000271442	1	0	BeFree
Agenesis of corpus callosum	0.000271442	1	0	BeFree
Congenital anomaly of brain	0.000271442	1	0	BeFree
Lissencephaly	0.000271442	1	0	BeFree
Congenital scoliosis	0.000271442	1	0	BeFree
Acquired scoliosis	0.000271442	1	0	BeFree
Congenital Fibrosis of the Extraocular Muscles	0.000271442	1	1	BeFree