TRIM21(tripartite motif containing 21) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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11p15.5-p15.3
基因染色体位置图

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因编码的三方母题(TRIM)家族中的一员。 TRIM的基序包括三个锌结合结构域,一个环,B框型1和B框2型,和一个卷曲螺旋区域。所编码的蛋白质是罗萨核糖核蛋白,它包括一个单一的多肽和四个小RNA分子中的一个的一部分。的罗萨颗粒定位于细胞质和细胞核两者。罗萨与患者舍格伦综合征和系统性红斑狼疮的自身抗原相互作用。此基因可变剪接转录物变体已有描述,但只有一个的全长性质已确定。 [由RefSeq的,2008年7月提供]

TRIM21基因的碱基序列:[NCBI]
TRIM21基因的碱基突变:           显示全部snp
rs15120       rs760217       rs890419       rs890420       rs915956       rs926100       rs926101       rs928913       rs928914       rs928915       rs1042302       rs1426377       rs1426378       rs2114294       rs2162297       rs2250241       rs2269328       rs2269329       rs2269330       rs2554931       rs2554932       rs2554933       rs2554934       rs2554937       rs2599585       rs2599586       rs2599587       rs2599588       rs2855140       rs2855141       rs2855142       rs2975162       rs4144331       rs5030768       rs5030769       rs5030770       rs5030771      
rs7930500       rs7947461       rs10553949       rs10700793       rs10767979       rs10767980       rs10835992       rs10835993       rs10835995       rs11032063       rs11032079       rs11032080       rs11032081       rs11032089       rs11820888       rs11824326       rs11825233       rs11825252       rs12224960       rs12365876       rs12797348       rs12802681       rs12804969       rs12805578       rs34490271       rs35064107       rs35225257       rs35747644       rs35757167       rs36233844       rs36233849       rs36233851       rs36233853       rs58403334       rs60659531       rs60923494       rs71050403       rs71466158       rs73431089       rs73431096       rs73431098       rs74051867       rs74051870       rs74521947       rs74731126       rs74954683       rs75124984       rs75731514       rs77179414       rs77715590       rs77872384       rs78007308       rs78450139       rs79828622       rs111343385       rs111784756       rs112509164       rs112534094       rs113021759       rs113054785       rs113127063       rs113257692       rs113923185       rs114189729       rs114238164       rs114299416       rs114384382       rs115001393       rs115701320       rs116087341       rs116118100       rs116261193       rs116383064       rs116501153       rs116996347       rs117196834       rs117975807       rs138109915       rs138239786       rs138617860       rs138696726       rs138869121       rs139535491       rs139553034       rs140181316       rs140446058       rs140627197       rs140922063       rs140930668       rs141654915       rs141711076       rs141750917       rs142506989       rs142674871       rs142721895       rs142902496       rs142945217       rs143020803       rs143500036       rs143540788       rs143635592       rs143673605       rs144327923       rs144776520       rs144810409       rs144863413       rs145064089       rs145390262       rs145449318       rs145492792       rs146276676       rs146783362       rs146831060       rs147202641       rs147379347       rs147713495       rs147945907       rs147968706       rs148028808       rs148564333       rs149004015       rs149532731       rs149584040       rs149874979       rs150067844       rs150168843       rs150401161       rs150693810       rs150873198       rs180688777       rs180770489       rs180986519       rs181476689       rs181651513       rs181907998       rs182258673       rs182386238       rs182514622       rs182872202       rs183101874       rs183163094       rs183275033       rs183782608       rs184052496       rs184091559       rs184325321       rs184562776       rs184690839       rs184842885       rs185337125       rs185380055       rs185586345       rs186130887       rs186235376       rs186319330       rs186330744       rs186517565       rs186621188       rs186987585       rs186999785       rs187226558       rs187544241       rs187897017       rs188191120       rs188631453       rs188668196       rs188900745       rs188925748       rs189391834       rs189655601       rs189912047       rs190194450       rs190716391       rs190812603       rs190949625       rs191125860       rs191306452       rs191427648       rs191468264       rs191510080       rs191749782       rs191809620       rs192184835       rs192535240       rs192836562       rs192937542       rs192953500       rs193182757       rs193258833       rs199497861       rs199516390       rs199739277       rs199774486       rs199881122       rs199890612       rs200023997       rs200080628       rs200123206       rs200455394       rs200488796       rs200627515       rs200781638       rs200908933       rs200911631       rs200983906       rs201211100       rs201359489       rs201475245       rs201525236       rs201531249       rs201583036       rs202232848       rs202233326       rs367633448       rs367660765       rs367901949       rs367934964       rs368240046       rs368375189       rs368447545       rs368467083       rs368582857       rs368774306       rs369388803       rs369422094       rs369693512       rs369699546       rs369722667       rs369768981       rs369901685       rs370385142       rs370527238       rs370592392       rs371266390       rs371366779       rs371899235       rs372054631       rs372074275       rs372176153       rs372399550       rs372452966       rs372518277       rs372599112       rs372780428       rs373050608       rs373117861       rs373243234       rs373283874       rs373285517       rs373364363       rs373606284       rs373774458       rs373852558       rs373961598       rs374313914       rs374402312       rs374814716       rs374900781       rs375099862       rs375488009       rs375521337       rs375673915       rs375865854       rs375985425       rs376066276       rs376171407       rs376214108       rs376293168       rs376821246       rs376885569       rs376900051       rs376986186       rs377182147       rs377387654       rs377501023       rs527377315       rs527590897       rs527714053       rs527789908       rs527989803       rs528198503       rs528530992       rs529215481       rs529342842       rs530319019       rs530413494       rs530449671       rs531144007       rs531361182       rs531499071       rs531626715       rs531646029       rs531700092       rs531970696       rs532727107       rs532789702       rs532866575       rs533131811       rs533135305       rs533188321       rs533190977       rs533277236       rs533277996       rs533354931       rs533811309       rs534229607       rs534418627       rs534434049       rs534553053       rs534690971       rs534754138       rs534828555       rs535321770       rs536288558       rs536288600       rs536750627       rs536758393       rs537427311       rs538020213       rs538683397       rs539348513       rs539421957       rs539693417       rs539753972       rs539765322       rs540786789       rs541277268       rs541305393       rs541594813       rs542131203       rs542386261       rs542572980       rs542711701       rs542767455       rs542848772       rs543046690       rs543334215       rs543897571       rs543920371       rs543956940       rs544318308       rs544981870       rs545046388       rs545146903       rs545971524       rs546240855       rs546762842       rs547926696       rs547954994       rs548616470       rs549151010       rs549174939       rs549212842       rs549300309       rs549409039       rs549472409       rs549624485       rs549756195       rs550058012       rs550093376       rs550101975       rs550206725       rs550751557       rs550929337       rs551403614       rs551597214       rs551716573       rs551825360       rs551884248       rs552410755       rs552877821       rs553019538       rs553319068       rs553396753       rs553543597       rs554312827       rs554404345       rs554477993       rs555094538       rs555759749       rs556338972       rs556551431       rs556850359       rs557066511       rs557140335       rs557147165       rs557190888       rs557236012       rs557277258       rs557318951       rs557922930       rs557979659       rs558058667       rs558134395       rs558986304       rs559124468       rs559844451       rs561132773       rs561284324       rs561418127       rs561476510       rs561680225       rs561736626       rs561870283       rs562513219       rs562964274       rs563622036       rs563900124       rs563912691       rs564066824       rs564729562       rs564806520       rs565344786       rs565482952       rs565788225       rs565889763       rs566364604       rs566839361       rs567017060       rs567288322       rs567494115       rs567781801       rs568120255       rs568133060       rs568181621       rs568319859       rs568990116       rs569051542       rs569078364       rs569124676       rs569554501       rs569773778       rs569915357       rs570080430       rs570325433       rs571738426       rs571947012       rs572010085       rs572010248       rs573034869       rs573125298       rs573316762       rs573455643       rs573635845       rs573773562       rs574639243       rs574672219       rs574904759       rs574966130       rs575009151       rs575447381       rs575522825       rs575692417       rs575786490       rs575850042       rs576034851       rs576376871       rs576600329       rs576974038       rs577257440       rs577400147       rs577581987       rs577652834       rs577937360       rs745306518       rs745527799       rs745654190       rs745775287       rs745821042       rs745944056       rs746167796       rs746385903       rs746514777       rs746569837       rs746990888       rs746993640       rs747023173       rs747163318       rs747249462       rs747376159       rs747427609       rs748100939       rs748221792       rs748278580       rs748392449       rs748535821       rs748768606       rs748866982       rs748908934       rs749094372       rs749552998       rs749957230       rs749988775       rs750110927       rs750164091       rs750415858       rs750469188       rs750591685       rs750740737       rs750871852       rs751114017       rs751244449       rs751308535       rs751374439       rs751472608       rs751589231       rs751644653       rs751699840       rs751868251       rs752020854       rs752141663       rs752319529       rs752371909       rs752471644       rs752491513       rs752772216       rs752823878       rs752950267       rs753047874       rs753153264       rs753283820       rs753499449       rs753740211       rs753861438       rs754083886       rs754138818       rs754288887       rs754702088       rs754776451       rs754895445       rs755084656       rs755138059       rs755279386       rs755296975       rs755390137       rs755499996       rs755718025       rs755771107       rs755938764       rs756063223       rs756408935       rs756422491       rs756475953       rs756633675       rs756760660       rs756850342       rs756903520       rs756905410       rs757286526       rs757330576       rs757512216       rs757664232       rs757789140       rs757990805       rs758420100       rs758567750       rs758692834       rs758865723       rs759072456       rs759097582       rs759221589       rs759240021       rs759245070       rs759346849       rs759398283       rs759524568       rs759649253       rs759731100       rs759997643       rs760050565       rs760072864       rs760201272       rs760380325       rs760428568       rs760763049       rs760818203       rs760943007       rs761038124       rs761094259       rs761097995       rs761110462       rs761253095       rs761322988       rs761356203       rs761529156       rs761579629       rs761757344       rs761952605       rs761961466       rs762085934       rs762386840       rs762590248       rs762673562       rs762711398       rs763082253       rs763346857       rs763724351       rs763772735       rs763776779       rs763897691       rs763993078       rs764093152       rs764424272       rs764560876       rs764736589       rs764825304       rs764861100       rs764916305       rs765134388       rs765218288       rs765432246       rs765439089       rs765612508       rs765720478       rs765947685       rs765999535       rs766328253       rs766464540       rs766590297       rs766661587       rs766746377       rs766961981       rs767066255       rs767110755       rs767150820       rs767200220       rs767202191       rs767378115       rs767725911       rs767901426       rs768080889       rs768115356       rs768184526       rs768291073       rs768291076       rs768706533       rs768746875       rs768929484       rs768958925       rs769094622       rs769612427       rs769627311       rs769687956       rs769850075       rs769975106       rs770081380       rs770220583       rs770341375       rs770396502       rs770667290       rs770993955       rs771068060       rs771338158       rs771338260       rs771391386       rs771477578       rs771514995       rs771600665       rs771699573       rs771928181       rs772058256       rs772111148       rs772234532       rs772420632       rs772731219       rs773061696       rs773126563       rs773361209       rs773455912       rs773541152       rs773558177       rs773666027       rs773682651       rs773856790       rs774073424       rs774180491       rs774196164       rs774319405       rs774369830       rs774529692       rs774581041       rs774600887       rs774725359       rs775371395       rs775435709       rs775781424       rs775898948       rs775954054       rs776241667       rs776314061       rs776394317       rs776489665       rs776517175       rs776518349       rs776665896       rs776919874       rs776971189       rs776974432       rs777037633       rs777092527       rs777095654       rs777154358       rs777389098       rs777735629       rs777791070       rs777844453       rs777869426       rs777871844       rs778014098       rs778184981       rs778239057       rs778286497       rs778330914       rs778413062       rs778585874       rs778606470       rs778729546       rs778973403       rs779395617       rs779456849       rs779489080       rs779542271       rs780484565       rs780689479       rs780814363       rs781137856       rs781227051       rs781258544       rs781299974       rs781370023       rs781763137       rs866452255      

TRIM21基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CTCTCCAGAACTCAGGAGTG
59
TCCAGAGTGATGTGGACTG
58
TACCTCTCCAGAACTCAGGA
59
AGAGTGATGTGGACTGCAC
59
ACCTCTCCAGAACTCAGGA
59
CAGAGTGATGTGGACTGCA
59
CATGTGCAGTCCACATCAC
59
TCCAAGCCTCACTTGTCTC
59
CATGTGCAGTCCACATCAC
59
TCTCCAAGCCTCACTTGTC
59
CATGTGCAGTCCACATCAC
59
TTCCAGGTATGCTCTGCTG
59
      尚未收录相关数据

TRIM21基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

TRIM21基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0000209
P19474(UniProtKB)
IDA
GO:0000209
P19474(UniProtKB)
TAS
GO:0000932
P19474(UniProtKB)
IEA
GO:0003677
P19474(UniProtKB)
IEA
GO:0003723
P19474(UniProtKB)
IEA
GO:0004842
P19474(UniProtKB)
IDA
GO:0004842
P19474(UniProtKB)
IDA
GO:0004842
P19474(UniProtKB)
IDA
GO:0004842
P19474(UniProtKB)
IDA
GO:0004842
P19474(UniProtKB)
EXP
GO:0004842
P19474(UniProtKB)
IDA
GO:0004842
P19474(UniProtKB)
TAS
GO:0004842
P19474(UniProtKB)
TAS
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005515
P19474(UniProtKB)
IPI
GO:0005634
P19474(UniProtKB)
IDA
GO:0005737
P19474(UniProtKB)
IDA
GO:0005737
P19474(UniProtKB)
IDA
GO:0005776
P19474(UniProtKB)
IEA
GO:0005829
P19474(UniProtKB)
TAS
GO:0005829
P19474(UniProtKB)
TAS
GO:0005829
P19474(UniProtKB)
TAS
GO:0005829
P19474(UniProtKB)
TAS
GO:0005829
P19474(UniProtKB)
TAS
GO:0005829
P19474(UniProtKB)
TAS
GO:0006513
P19474(UniProtKB)
IDA
GO:0006513
P19474(UniProtKB)
IDA
GO:0007049
P19474(UniProtKB)
IEA
GO:0008270
P19474(UniProtKB)
IEA
GO:0010508
P19474(UniProtKB)
IMP
GO:0016567
P19474(UniProtKB)
IDA
GO:0016567
P19474(UniProtKB)
IDA
GO:0016567
P19474(UniProtKB)
IDA
GO:0016874
P19474(UniProtKB)
IEA
GO:0030529
P19474(UniProtKB)
TAS
GO:0031410
P19474(UniProtKB)
IEA
GO:0031648
P19474(UniProtKB)
IMP
GO:0032088
P19474(UniProtKB)
IDA
GO:0032479
P19474(UniProtKB)
TAS
GO:0032897
P19474(UniProtKB)
IDA
GO:0034341
P19474(UniProtKB)
IDA
GO:0042802
P19474(UniProtKB)
IPI
GO:0042802
P19474(UniProtKB)
IPI
GO:0042802
P19474(UniProtKB)
IPI
GO:0045087
P19474(UniProtKB)
IDA
GO:0045787
P19474(UniProtKB)
IMP
GO:0046598
P19474(UniProtKB)
IEA
GO:0051091
P19474(UniProtKB)
IDA
GO:0051865
P19474(UniProtKB)
IDA
GO:0060333
P19474(UniProtKB)
TAS
GO:0070206
P19474(UniProtKB)
IDA
GO:0090086
P19474(UniProtKB)
IMP
GO:1902187
P19474(UniProtKB)
IDA
GO:0019005
P19474(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控TRIM21基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Lupus Erythematosus, Systemic 0.022473594 55 5 BeFree_GAD_LHGDN
Sjogren's Syndrome 0.016445791 9 0 BeFree_GAD_LHGDN
Autoimmune Diseases 0.009520329 16 0 BeFree_LHGDN
Neonatal Systemic lupus erythematosus 0.007600372 28 0 BeFree
Congenital heart block 0.007328931 27 0 BeFree
Lupus Erythematosus 0.004885954 18 0 BeFree
Lupus Erythematosus, Discoid 0.003800186 14 0 BeFree
Lupus Vulgaris 0.003528744 13 0 BeFree
Hyperplastic Polyp 0.002985861 11 0 BeFree
Sessile Serrated Adenoma/Polyp 0.002985861 11 0 BeFree
Squamous cell carcinoma 0.00272435 1 0 LHGDN
Cessation of life 0.00272435 1 0 LHGDN
Anemia, Sickle Cell 0.002638474 1 1 BeFree_GAD
polyps 0.002442977 9 0 BeFree
Malignant neoplasm of ovary 0.002367032 1 0 GAD
Adenoma 0.001900093 7 0 BeFree
Rheumatoid Arthritis 0.001628651 6 0 BeFree
Rheumatism 0.001628651 6 0 BeFree
Traditional Serrated Adenoma 0.001628651 6 0 BeFree
Malignant tumor of colon 0.000814326 3 0 BeFree
Colorectal Carcinoma 0.000814326 3 1 BeFree
Heart Block 0.000814326 3 0 BeFree
HIV Infections 0.000814326 3 0 BeFree
Lupus Erythematosus, Subacute Cutaneous 0.000814326 3 0 BeFree
Dermatologic disorders 0.000814326 3 0 BeFree
Dermatomyositis 0.000542884 2 0 BeFree
Familial Mediterranean Fever 0.000542884 2 0 BeFree
Pituitary Neoplasms 0.000542884 2 0 BeFree
Adenomatous Polyposis Coli 0.000542884 2 0 BeFree
Sicca Syndrome 0.000542884 2 0 BeFree
Primary Sj�gren's syndrome 0.000542884 2 0 BeFree
Multiple polyps 0.000542884 2 0 BeFree
Colon Carcinoma 0.000542884 2 0 BeFree
Colorectal Cancer 0.000542884 2 0 BeFree
Amyloidosis 0.000271442 1 0 BeFree
Arthritis 0.000271442 1 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Bronchiectasis 0.000271442 1 0 BeFree
Dermatitis 0.000271442 1 0 BeFree
Graves Disease 0.000271442 1 0 BeFree
Arthropathy 0.000271442 1 0 BeFree
Kidney Diseases 0.000271442 1 0 BeFree
leukemia 0.000271442 1 0 BeFree
Leukopenia 0.000271442 1 0 BeFree
Lung diseases 0.000271442 1 0 BeFree
Lupus Erythematosus, Cutaneous 0.000271442 1 0 BeFree
Myositis 0.000271442 1 0 BeFree
Degenerative polyarthritis 0.000271442 1 0 BeFree
Pituitary Adenoma 0.000271442 1 0 BeFree
Pleural effusion disorder 0.000271442 1 0 BeFree
Raynaud Disease 0.000271442 1 0 BeFree
Rectal Neoplasms 0.000271442 1 0 BeFree
RNA Virus Infections 0.000271442 1 0 BeFree
Scarlet Fever 0.000271442 1 0 BeFree
Sialadenitis 0.000271442 1 0 BeFree
Skin lesion 0.000271442 1 0 BeFree
Gastric ulcer 0.000271442 1 0 BeFree
Thyroiditis 0.000271442 1 0 BeFree
Chagas Disease 0.000271442 1 0 BeFree
Viremia 0.000271442 1 0 BeFree
Virus Diseases 0.000271442 1 0 BeFree
Small cell carcinoma of lung 0.000271442 1 0 BeFree
Adenomatous Polyps 0.000271442 1 0 BeFree
Adult type dermatomyositis 0.000271442 1 0 BeFree
Annular Erythema 0.000271442 1 0 BeFree
Malignant neoplasm of lung 0.000271442 1 0 BeFree
Mucosa-Associated Lymphoid Tissue Lymphoma 0.000271442 1 0 BeFree
Systemic amyloidosis 0.000271442 1 0 BeFree
Primary Systemic Amyloidosis 0.000271442 1 0 BeFree
Tubulovillous adenoma 0.000271442 1 0 BeFree
Streptococcal toxic shock syndrome 0.000271442 1 0 BeFree
Chronic Chagas' disease 0.000271442 1 0 BeFree
Immune thrombocytopenic purpura 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Carcinoma of lung 0.000271442 1 0 BeFree
lupus cutaneous 0.000271442 1 0 BeFree
Idiopathic Inflammatory Myopathies 0.000271442 1 0 BeFree
Alloimmunisation 0.000271442 1 1 BeFree
Lupus erythematosus overlap syndrome 0.000271442 1 0 BeFree
Rectal Tumors 0.000271442 1 0 BeFree
Non-Neoplastic Disorder 0.000271442 1 0 BeFree
PHOTOPAROXYSMAL RESPONSE 1 0.000271442 1 0 BeFree
Subacute cutaneous lupus 0.000271442 1 0 BeFree
Serrated polyp 0.000271442 1 0 BeFree
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