TPI1(triosephosphate isomerase 1) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

12p13.31
基因染色体位置图

基因简述

基因简述

This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

[中文简述(自动翻译):]  该基因编码一种酶，它由两个相同的蛋白质，其催化在糖酵解和糖异生-3-磷酸（G3P）和二羟基丙酮磷酸（DHAP）甘油的异构化的。在这种基因突变与磷酸丙糖异构酶缺乏有关。假基因已被确定在6染色体1,4，并在多个转录变异体7选择性剪接的结果。 [由RefSeq的，2009年4月提供]

OMIM数据库中对TPI1基因的介绍     Wikipedia数据库中对TPI1基因的介绍

基因序列

基因序列

TPI1基因的碱基序列：[NCBI]

基因突变

基因突变

TPI1基因的碱基突变：           显示全部snp
rs14183       rs1053521       rs1804540       rs1804541       rs1804544       rs3178452       rs11064435       rs11064436       rs58194764       rs61733179       rs61733180       rs72661112       rs76935190       rs80107871       rs111998918       rs114310136       rs139707997       rs144171030       rs148245028       rs151110609       rs187539053       rs199775938       rs200625865       rs368362101       rs368797936       rs370177231       rs370858567       rs373614647       rs374447674       rs375936158       rs376899563       rs377186570       rs540279409       rs572293654       rs781784943       rs781789953       rs781796397      
rs781821197       rs781826089       rs781847533       rs781903023       rs781906850       rs781909549       rs781917369       rs781928255       rs781953805       rs781962434       rs781970120       rs781970439       rs781970835       rs781972837       rs781976884       rs781983074       rs781990300       rs782003905       rs782007841       rs782016331       rs782019761       rs782024229       rs782027670       rs782032794       rs782052523       rs782061169       rs782068182       rs782075236       rs782075884       rs782076812       rs782077087       rs782080571       rs782083020       rs782107285       rs782136697       rs782159093       rs782165017       rs782167675       rs782174482       rs782174771       rs782181290       rs782187545       rs782201360       rs782235181       rs782236235       rs782256729       rs782265782       rs782268446       rs782273202       rs782276059       rs782279227       rs782279875       rs782308993       rs782320346       rs782327377       rs782328048       rs782334545       rs782336797       rs782347100       rs782363879       rs782410612       rs782416750       rs782428891       rs782436235       rs782437142       rs782448562       rs782486049       rs782490594       rs782503144       rs782508499       rs782514862       rs782521294       rs782521774       rs782521998       rs782536936       rs782544484       rs782571455       rs782574769       rs782582888       rs782598668       rs782599241       rs782606362       rs782607948       rs782625239       rs782643494       rs782648651       rs782663163       rs782682981       rs782684621       rs782700403       rs782702950       rs782727122       rs782730165       rs782730215       rs782737507       rs782764628       rs782784554       rs782793367       rs782795395       rs782802899       rs782803867       rs12692       rs1800200       rs1800201       rs1800202       rs1804542       rs2001004       rs2001005       rs2071064       rs2071065       rs2071066       rs2071067       rs2071068       rs2071069       rs3174612       rs3182461       rs4334119       rs7977645       rs11064434       rs11447131       rs11548737       rs11548744       rs12302749       rs17851580       rs60115912       rs60219247       rs61747602       rs72661105       rs72661107       rs72661109       rs73260840       rs78059433       rs78922406       rs79239224       rs111817525       rs113502733       rs115061797       rs121964845       rs121964846       rs121964848       rs138131191       rs138858865       rs139532537       rs139592683       rs140575874       rs141765645       rs141972556       rs142385593       rs142476239       rs143000041       rs143305139       rs145623271       rs147386979       rs148609987       rs149190846       rs149291504       rs149531901       rs150585849       rs151294895       rs181882616       rs188138723       rs199634350       rs199765467       rs199881593       rs199997096       rs200230028       rs200692430       rs201185301       rs201432576       rs202136630       rs367659240       rs367933825       rs367943206       rs368392340       rs368437920       rs368497510       rs369077745       rs369241009       rs369600918       rs369693539       rs369720680       rs369734826       rs370795160       rs370863694       rs370910772       rs371216138       rs371951126       rs372525956       rs372736626       rs372777292       rs373087863       rs373282561       rs373452929       rs374074904       rs374331353       rs374785767       rs374913421       rs375230418       rs375321131       rs375712848       rs376401954       rs377304798       rs377417359       rs530718769       rs531909445       rs531936696       rs540692865       rs553657239       rs750321511       rs756085366       rs781787665       rs781795779       rs781799706       rs781815674       rs781822291       rs781825619       rs781833277       rs781835924       rs781843297       rs781843757       rs781847631       rs781855208       rs781855597       rs781857059       rs781862806       rs781864765       rs781865717       rs781876052       rs781876590       rs781878443       rs781883266       rs781886049       rs781891192       rs781891571       rs781891860       rs781893698       rs781900442       rs781906708       rs781911173       rs781916273       rs781933652       rs781936323       rs781936880       rs781938767       rs781944509       rs781944856       rs781949460       rs781952795       rs781954607       rs781958622       rs781965806       rs781975436       rs781985611       rs781990734       rs781995747       rs782011090       rs782014411       rs782018940       rs782032967       rs782035473       rs782039652       rs782042516       rs782045283       rs782049114       rs782053705       rs782054747       rs782063657       rs782077862       rs782091883       rs782099400       rs782101903       rs782104397       rs782108587       rs782109366       rs782118432       rs782119804       rs782123152       rs782129667       rs782131436       rs782131797       rs782151989       rs782153172       rs782153322       rs782155888       rs782157169       rs782165630       rs782166025       rs782167291       rs782174861       rs782180796       rs782181569       rs782182078       rs782190000       rs782193329       rs782199292       rs782200689       rs782201182       rs782210903       rs782211851       rs782212846       rs782221774       rs782225455       rs782228552       rs782231885       rs782236879       rs782238701       rs782244635       rs782254346       rs782260176       rs782267337       rs782274007       rs782290345       rs782290899       rs782292188       rs782306307       rs782307766       rs782311093       rs782316890       rs782326997       rs782339549       rs782349793       rs782356307       rs782359362       rs782360081       rs782377031       rs782382390       rs782386647       rs782390162       rs782390600       rs782391534       rs782393784       rs782410070       rs782415919       rs782417309       rs782418475       rs782419508       rs782421589       rs782429740       rs782439716       rs782442019       rs782447279       rs782449445       rs782462272       rs782463337       rs782466281       rs782468096       rs782469528       rs782470616       rs782473639       rs782474342       rs782476724       rs782478123       rs782478879       rs782482721       rs782509336       rs782523416       rs782526244       rs782535920       rs782539657       rs782542150       rs782543276       rs782547955       rs782561391       rs782562374       rs782568441       rs782569395       rs782580053       rs782582302       rs782583048       rs782584234       rs782592225       rs782594721       rs782602536       rs782615896       rs782617398       rs782618474       rs782622700       rs782626649       rs782637300       rs782639875       rs782651515       rs782654635       rs782657528       rs782663828       rs782668491       rs782668684       rs782672720       rs782680636       rs782680893       rs782689272       rs782698449       rs782703710       rs782704781       rs782705224       rs782707197       rs782715413       rs782716538       rs782720685       rs782725599       rs782728250       rs782729595       rs782733136       rs782734263       rs782738548       rs782753293       rs782755026       rs782757472       rs782758079       rs782758624       rs782759986       rs782768995       rs782772941       rs782774337       rs782778927       rs782789697       rs782796123       rs782801396       rs782808812       rs782809470       rs782812310       rs782814216       rs782816823       rs782819118      

基因表达

基因表达

TPI1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CATGATCAAAGACTGCGGA
57
CCCAATCAGCTCATCTGAC
58
TGGCATGATCAAAGACTGC
59
CCCAATCAGCTCATCTGAC
58
TTTATGGAGGCTCTGTGACTG
60
GATGATGTCCACGAATTCGG
59
TTATGGAGGCTCTGTGACTG
59
GATGATGTCCACGAATTCGG
59
GGAGAAGCTAGATGAAAGGG
58
TTCACGTTATCTGCGATGAC
59
AGATAACGTGAAGGACTGGA
58
AGAACAAGAAGCTGTTGGG
58
TTATGGAGGCTCTGTGACTG
59
GATGATGTCCACGAATTCGG
59
TTTATGGAGGCTCTGTGACTG
60
GATGATGTCCACGAATTCGG
59
ATTTATGGAGGCTCTGTGAC
57
ATGATGTCCACGAATTCGG
58
TTTATGGAGGCTCTGTGACTG
60
GATGATGTCCACGAATTCGG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

TPI1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

TPI1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0004807
P60174(UniProtKB)
TAS
GO:0004807
P60174(UniProtKB)
NAS
GO:0004807
P60174(UniProtKB)
EXP
GO:0005515
P60174(UniProtKB)
IPI
GO:0005515
P60174(UniProtKB)
IPI
GO:0005615
P60174(UniProtKB)
IDA
GO:0005615
P60174(UniProtKB)
IDA
GO:0005615
P60174(UniProtKB)
IDA
GO:0005634
P60174(UniProtKB)
IDA
GO:0005829
P60174(UniProtKB)
IBA
GO:0005829
P60174(UniProtKB)
TAS
GO:0005829
P60174(UniProtKB)
TAS
GO:0006094
P60174(UniProtKB)
IBA
GO:0006094
P60174(UniProtKB)
IEA
GO:0006094
P60174(UniProtKB)
TAS
GO:0006096
P60174(UniProtKB)
IBA
GO:0006098
P60174(UniProtKB)
IEA
GO:0007275
P60174(UniProtKB)
IEA
GO:0019563
P60174(UniProtKB)
IBA
GO:0031625
P60174(UniProtKB)
IPI
GO:0046166
P60174(UniProtKB)
IBA
GO:0061621
P60174(UniProtKB)
TAS
GO:0070062
P60174(UniProtKB)
IDA
GO:0070062
P60174(UniProtKB)
IDA
GO:0070062
P60174(UniProtKB)
IDA
GO:0004807
U3KPS5(UniProtKB)
IEA
GO:0006094
U3KPS5(UniProtKB)
IEA
GO:0006096
U3KPS5(UniProtKB)
IEA
GO:0006098
U3KPS5(UniProtKB)
IEA
GO:0004807
U3KPZ0(UniProtKB)
IEA
GO:0006094
U3KPZ0(UniProtKB)
IEA
GO:0006096
U3KPZ0(UniProtKB)
IEA
GO:0006098
U3KPZ0(UniProtKB)
IEA
GO:0004807
U3KQF3(UniProtKB)
IEA
GO:0006094
U3KQF3(UniProtKB)
IEA
GO:0006096
U3KQF3(UniProtKB)
IEA
GO:0006098
U3KQF3(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控TPI1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Triosephosphate Isomerase Deficiency 0.24 3 8 CLINVAR_UNIPROT
Anemia, Hemolytic 0.121628651 7 0 BeFree_CTD_human
Triose phosphate isomerase deficiency 0.120542884 2 0 BeFree_ORPHANET
Alzheimer's Disease 0.12 1 0 CTD_human
Anemia, Hemolytic, Congenital Nonspherocytic 0.12 1 0 CTD_human
Squamous cell carcinoma 0.12 1 0 CTD_human
Inborn Errors of Metabolism 0.12 2 0 CTD_human
Mouth Neoplasms 0.12 1 0 CTD_human
Neuromuscular Diseases 0.12 1 0 CTD_human
Osteoporosis 0.12 1 0 CTD_human
Squamous cell carcinoma of esophagus 0.12 1 0 CTD_human
Neuromuscular Manifestations 0.12 2 0 CTD_human
Giardiasis 0.004614512 17 0 BeFree
melanoma 0.003267234 2 0 BeFree_LHGDN
Degenerative polyarthritis 0.002995792 1 0 BeFree_LHGDN
Multiple Sclerosis 0.00272435 1 0 LHGDN
Malaria 0.002367032 1 0 GAD
Asthma 0.002171535 8 0 BeFree
Cyst 0.001085767 4 0 BeFree
nervous system disorder 0.001085767 4 0 BeFree
Lupus Erythematosus, Systemic 0.000814326 3 0 BeFree
Neurologic Symptoms 0.000814326 3 0 BeFree
Enzymopathy 0.000814326 3 0 BeFree
Adenocarcinoma 0.000542884 2 0 BeFree
Colorectal Carcinoma 0.000542884 2 0 BeFree
Glioma 0.000542884 2 0 BeFree
Metabolic Diseases 0.000542884 2 0 BeFree
Neoplasm Metastasis 0.000542884 2 0 BeFree
Chagas Disease 0.000542884 2 0 BeFree
Malnutrition 0.000542884 2 0 BeFree
Coinfection 0.000542884 2 0 BeFree
Multisystem disorder 0.000542884 2 0 BeFree
Mammary Neoplasms 0.000542884 2 0 BeFree
Colorectal Cancer 0.000542884 2 0 BeFree
Anemia, Hemolytic, Congenital 0.000271442 1 0 BeFree
Autoimmune Diseases 0.000271442 1 0 BeFree
Dyskinetic syndrome 0.000271442 1 0 BeFree
Myeloid Leukemia, Chronic 0.000271442 1 0 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
Obesity 0.000271442 1 0 BeFree
Pseudorabies 0.000271442 1 0 BeFree
Schizophrenia 0.000271442 1 0 BeFree
Tumor Progression 0.000271442 1 0 BeFree
Uveal melanoma 0.000271442 1 0 BeFree
Psychiatric symptom 0.000271442 1 0 BeFree
Abnormal involuntary movement 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
MOHR-TRANEBJAERG SYNDROME 0.000271442 1 0 BeFree
Tumor Immunity 0.000271442 1 0 BeFree
Liver carcinoma 0.000271442 1 0 BeFree
Allergic disposition 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

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