TNFRSF10C(tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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8p22-p21
基因染色体位置图

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质是TNF受体超家族的成员。该受体包含胞外TRAIL结合结构域和跨膜结构域,但没有胞质死亡域。该受体是不能够诱导细胞凋亡的,并且被认为充当保护细胞免于TRAIL诱导的细胞凋亡的拮抗受体。该基因被认为是一个p53-调节的DNA损伤 - 诱导型基因。在许多正常组织中检测到该基因的表达,但在大多数肿瘤细胞系,这可以解释癌细胞的具体灵敏度对TRAIL的细胞凋亡诱导活性。 [由RefSeq的,2008年7月提供]

TNFRSF10C基因的碱基序列:[NCBI]
TNFRSF10C基因的碱基突变:           显示全部snp
rs4383965       rs6557616       rs7813716       rs10107826       rs10107827       rs10109912       rs11780032       rs12544760       rs12547716       rs12549481       rs12681513       rs35426677       rs41308116       rs41308120       rs41308122       rs41308124       rs56019891       rs56382118       rs60368371       rs73546635       rs73546636       rs73546638       rs73546640       rs74916009       rs79217773       rs79927591       rs114604664       rs114834960       rs114840021       rs115448886       rs115509505       rs116626968       rs138054216       rs138717492       rs139576559       rs142703178       rs144215650      
rs145907450       rs146654287       rs146758263       rs147339954       rs147367612       rs149504662       rs150354487       rs150688546       rs181222180       rs181454750       rs182224673       rs183847532       rs184319455       rs187592509       rs188421864       rs189060592       rs189304439       rs191930177       rs192021142       rs192812148       rs200834372       rs201043843       rs202073599       rs373433521       rs374416537       rs375556643       rs376883302       rs527671396       rs528245200       rs529446081       rs530485709       rs530524743       rs532123835       rs533553048       rs534592616       rs534839554       rs535601755       rs536129795       rs538021948       rs538336536       rs538418731       rs538586586       rs538748280       rs538796411       rs539153596       rs540183283       rs541183896       rs541373219       rs543343178       rs543379283       rs543523607       rs543949739       rs545281155       rs545391984       rs545833059       rs546655349       rs547667296       rs548064428       rs548099663       rs549123394       rs549923517       rs550361737       rs550472638       rs550602437       rs550790268       rs551130645       rs552639242       rs553195395       rs553308115       rs553394924       rs555388756       rs555446469       rs555485906       rs557477628       rs557531710       rs559652453       rs560860754       rs561532456       rs562376584       rs563836455       rs563981381       rs564617471       rs564714227       rs567337146       rs567484610       rs568308163       rs568355848       rs569630835       rs570159653       rs571389726       rs571419160       rs571548402       rs571706385       rs572751286       rs573070936       rs573675786       rs575888581       rs576013604       rs576204716       rs576365592       rs578016948       rs745871048       rs746296794       rs746828488       rs747998096       rs748771783       rs749131720       rs749350165       rs749401672       rs749917314       rs749970368       rs750985941       rs751517273       rs751935806       rs753358905       rs754785831       rs755715841       rs755767093       rs756251277       rs758367362       rs761318825       rs761836338       rs761937814       rs762545901       rs763298362       rs763782406       rs764957375       rs765008503       rs765750513       rs765919077       rs766403456       rs766893658       rs767839866       rs767975049       rs768889759       rs769829841       rs770068358       rs770863626       rs772651288       rs773054150       rs773227509       rs774975007       rs775672929       rs775855323       rs775931934       rs776763718       rs777280278       rs778899171       rs779941521       rs780177028       rs780792551       rs4077341       rs4242389       rs4620285       rs4871847       rs4871848       rs4871849       rs4872053       rs4872054       rs5890089       rs6983837       rs9314261       rs9644063       rs9918919       rs10081590       rs10081591       rs10086343       rs10103755       rs10111172       rs10111196       rs10113463       rs11135698       rs11135699       rs11135700       rs11776990       rs11779793       rs11780493       rs11780526       rs11785284       rs11786012       rs11987606       rs11994916       rs12115044       rs12545386       rs12546235       rs12546238       rs12547853       rs12550101       rs12550596       rs12550612       rs12550828       rs12679877       rs12681965       rs13256465       rs28507466       rs28622898       rs28626664       rs28653731       rs34115251       rs35714727       rs41308126       rs55670810       rs56263402       rs57028664       rs57125788       rs57655930       rs58181527       rs59583145       rs61736402       rs61736404       rs61736405       rs61736406       rs61756239       rs62501086       rs71546848       rs71546849       rs72577335       rs73222544       rs73222547       rs73222549       rs73222550       rs73546646       rs73546658       rs73546661       rs73546663       rs73671011       rs73671012       rs74480765       rs74519278       rs74766964       rs76077650       rs76324416       rs76364171       rs76666473       rs76870796       rs77395967       rs77550204       rs77797208       rs78394038       rs78780090       rs78875129       rs78985372       rs79063284       rs79221634       rs79792455       rs80118912       rs80132458       rs111238248       rs111461453       rs111474434       rs113644198       rs113806746       rs114029126       rs114123389       rs114139410       rs114291970       rs114358398       rs114703383       rs115512541       rs115810970       rs116036441       rs116371039       rs117020629       rs117325737       rs117919015       rs118099793       rs137941902       rs138041234       rs138474473       rs138726730       rs138827637       rs138944302       rs139562092       rs139634817       rs139657865       rs139720010       rs140224404       rs140743989       rs140895906       rs141199756       rs141315739       rs141950188       rs142209925       rs142214995       rs142225105       rs142274840       rs142617596       rs143037062       rs143453524       rs143618503       rs143879407       rs144307894       rs144392720       rs144414753       rs144435131       rs144550442       rs144796506       rs144951380       rs145102032       rs145913186       rs145921851       rs146356614       rs146389675       rs146592155       rs146676402       rs146934663       rs147815085       rs147844220       rs148006286       rs148373527       rs148394266       rs148732955       rs149046307       rs149134833       rs149237649       rs149451229       rs149479140       rs149927848       rs150076395       rs150233483       rs150502977       rs150817007       rs151009631       rs151183242       rs151239314       rs180786997       rs180844548       rs181112688       rs181323638       rs181484998       rs181817578       rs181921509       rs181953454       rs182167961       rs182209132       rs182522627       rs182744474       rs182795828       rs183098469       rs183117128       rs183117770       rs183881733       rs184025419       rs184085152       rs184517096       rs184766318       rs184776790       rs184947953       rs185011294       rs185317419       rs185606887       rs185688640       rs185889948       rs185909703       rs185966247       rs186114162       rs186171107       rs186386083       rs186423769       rs186450845       rs186489589       rs186778674       rs187243695       rs187352299       rs187650002       rs188158526       rs188200254       rs188359528       rs188420928       rs188525097       rs189018956       rs189028473       rs189050090       rs189227243       rs189425384       rs189841694       rs190049388       rs190053767       rs190368663       rs190621071       rs190637563       rs190808715       rs190910587       rs190914562       rs190923800       rs191427555       rs191458527       rs191690027       rs191734702       rs191735809       rs192032612       rs192254979       rs192519985       rs192543050       rs192946577       rs192981914       rs193078640       rs193110500       rs199708872       rs200178922       rs200276762       rs201292747       rs201593663       rs201656774       rs367585898       rs367722416       rs367809672       rs368040657       rs368157714       rs368955267       rs369052302       rs369615757       rs370285957       rs370518771       rs370555266       rs370853616       rs371065044       rs371351067       rs371508678       rs371608492       rs371758644       rs372298232       rs372467352       rs372724289       rs373458956       rs373741720       rs374294925       rs374335215       rs374621465       rs374765880       rs375141728       rs375147425       rs375148091       rs375435737       rs375537118       rs375799203       rs376263371       rs376360379       rs376900291       rs376981315       rs377096070       rs397762355       rs398007232       rs527895504       rs527956714       rs528019858       rs528224937       rs528425627       rs528448424       rs528832119       rs529037304       rs529548156       rs529840739       rs529927863       rs529965984       rs529986814       rs530080726       rs530184217       rs530196821       rs530243846       rs530338838       rs530505889       rs530651358       rs531419135       rs532064786       rs532255696       rs532315923       rs532542707       rs532632780       rs533102458       rs533293214       rs533496789       rs533512788       rs533523075       rs534486840       rs534542696       rs534645921       rs534790502       rs535057107       rs535177267       rs535208267       rs535432431       rs535511451       rs535806622       rs535836626       rs536420142       rs537005361       rs537195628       rs537222381       rs537354620       rs537552985       rs537563838       rs538140263       rs538177309       rs538577963       rs539190617       rs539348727       rs539417566       rs539521002       rs539775397       rs539932508       rs540068665       rs540565862       rs540661682       rs541316377       rs541380419       rs541714802       rs541817913       rs541912418       rs541962744       rs542096893       rs542347675       rs543509981       rs543655241       rs543716456       rs543757352       rs544113540       rs544167911       rs544172271       rs544402235       rs544654656       rs544742809       rs545147253       rs545732132       rs545998659       rs546020941       rs546020992       rs546115188       rs546125824       rs546257009       rs546447341       rs546583393       rs546710297       rs547073184       rs547194572       rs547261171       rs547473407       rs548683983       rs548881444       rs549304275       rs549391638       rs549472786       rs549625116       rs549799768       rs550086162       rs550423624       rs551082774       rs551119605       rs551244834       rs551270102       rs551457137       rs551618727       rs551651079       rs551804659       rs552167044       rs552472843       rs552537157       rs553553731       rs553558286       rs553589568       rs553676578       rs553728402       rs553795958       rs553991461       rs554080631       rs554312098       rs554531839       rs554580958       rs554997310       rs555157240       rs555268318       rs555308479       rs555411439       rs555533716       rs555588566       rs555662355       rs555787091       rs555793210       rs556929475       rs556937662       rs557323677       rs557660768       rs557692765       rs557697792       rs557780053       rs557841353       rs558033673       rs558057961       rs558950928       rs560324206       rs560324770       rs560337942       rs560529897       rs560713846       rs560792212       rs561350670       rs562215578       rs562339066       rs562902278       rs563306996       rs563339509       rs564216865       rs564293884       rs564376234       rs564378451       rs564589384       rs564767321       rs565256301       rs565318014       rs565457360       rs565554302       rs565736756       rs565868783       rs565906367       rs565998080       rs566155267       rs566858560       rs567052207       rs567068485       rs567344015       rs567366262       rs567432443       rs567689148       rs567735348       rs567787323       rs568095673       rs568183505       rs568369095       rs568475644       rs569331394       rs569479790       rs569490134       rs569734366       rs569858474       rs569870682       rs569943519       rs569965085       rs570105244       rs570115749       rs570241629       rs570692586       rs570707458       rs571171663       rs571650738       rs571859708       rs571891814       rs572007407       rs572098079       rs572319629       rs572372428       rs572629963       rs572737157       rs572820719       rs573287754       rs574024461       rs574073873       rs574113971       rs574141200       rs574153058       rs574234429       rs574325035       rs574460616       rs574506655       rs574595619       rs574691767       rs574762885       rs574824749       rs574923948       rs575216067       rs575315585       rs576010346       rs576172369       rs576248058       rs576435133       rs576559270       rs576642743       rs576698572       rs576746725       rs576793487       rs577124879       rs577343178       rs577728452       rs578206717       rs578256896       rs745327005       rs745598625       rs745623851       rs745676763       rs745711773       rs746229328       rs746450836       rs746539479       rs746578253       rs747121963       rs747257276       rs747339712       rs747394784       rs747582356       rs748176331       rs748188644       rs748242070       rs748753752       rs748768602       rs748874087       rs749028641       rs749250247       rs749334327       rs749935385       rs750441460       rs750495872       rs750542227       rs750595163       rs751283485       rs751335392       rs751449517       rs751669654       rs751720849       rs752180102       rs752275283       rs752403697       rs752739418       rs752809788       rs753364935       rs753614644       rs753669696       rs753811488       rs753883363       rs754257856       rs754615566       rs754666961       rs755135173       rs755286713       rs755521340       rs755530473       rs755953492       rs756368482       rs756413549       rs756572473       rs756775757       rs756783539       rs756963326       rs757263611       rs757298267       rs757301163       rs757414723       rs757511052       rs757516121       rs758206099       rs758400646       rs758548166       rs758954700       rs758980677       rs759007730       rs759567056       rs759894144       rs760291565       rs760412502       rs760461365       rs760463641       rs760628420       rs761322514       rs762137895       rs762380926       rs762479117       rs762616454       rs762635342       rs763257054       rs763286890       rs763312157       rs763811896       rs763993562       rs764310730       rs764474080       rs765149128       rs765274335       rs765340449       rs765395631       rs765412277       rs765704626       rs766286657       rs766540863       rs766646337       rs766720181       rs766998424       rs767213244       rs767359470       rs767521985       rs768091764       rs768309368       rs768607487       rs768688303       rs769431508       rs769594904       rs769703217       rs769802766       rs770468681       rs770540760       rs770729106       rs770739192       rs770782171       rs770978278       rs771207106       rs771444221       rs771607229       rs772398109       rs772423882       rs772468769       rs772582578       rs772871441       rs772943623       rs773599759       rs773652777       rs773950868       rs774005282       rs774281296       rs774856690       rs775326199       rs775676498       rs775815172       rs776117539       rs776274310       rs777138418       rs777347835       rs777523887       rs777769881       rs777959460       rs778256901       rs778804388       rs778899323       rs779159813       rs779287560       rs779689658       rs779898868       rs780432942       rs780610147       rs780656224       rs780785336       rs781215745       rs781428318       rs781658815       rs781724230       rs781750714      

TNFRSF10C基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GACCCTAAAGTTCGTCGTC
58
GTTCTGATCTATGAGATCTGGC
58
TAACCTGTGATTCCTGGCT
58
CCAATGAGCTTCCAACTCC
58
TTCTTGCTTCCCATGTACAG
57
TGTGTCTCTGGTCATGGTG
59
GAGTGTCCAGCAGGATCTC
59
GGAAGCGTTGGTGTAATCC
58
TTAACCTGTGATTCCTGGCT
59
CAATGAGCTTCCAACTCCC
58
GAGTGTCCAGCAGGATCTC
59
GAAGCGTTGGTGTAATCCAC
59
CCCAAGACCCTAAAGTTCG
57
GATCTATGAGATCTGGCAGC
57
TCTTGCTTCCCATGTACAG
57
CTGTGTCTCTGGTCATGGT
59
GAGTGTCCAGCAGGATCTC
59
ATTGTTGGAAGCGTTGGTG
59
TTCTTGCTTCCCATGTACAG
57
CTGTGTCTCTGGTCATGGT
59
      尚未收录相关数据

TNFRSF10C基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

TNFRSF10C基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004888
O14798(UniProtKB)
TAS
GO:0005031
O14798(UniProtKB)
IBA
GO:0005886
O14798(UniProtKB)
TAS
GO:0005887
O14798(UniProtKB)
TAS
GO:0006954
O14798(UniProtKB)
IBA
GO:0006955
O14798(UniProtKB)
IBA
GO:0007165
O14798(UniProtKB)
TAS
GO:0007275
O14798(UniProtKB)
IBA
GO:0008625
O14798(UniProtKB)
IBA
GO:0031225
O14798(UniProtKB)
IEA
GO:0032496
O14798(UniProtKB)
IBA
GO:0033209
O14798(UniProtKB)
IEA
GO:0042127
O14798(UniProtKB)
IBA
GO:0042981
O14798(UniProtKB)
IBA
GO:0042981
O14798(UniProtKB)
TAS
GO:0045569
O14798(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控TNFRSF10C基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Juvenile arthritis 0.12 1 0 CTD_human
Prostatic Neoplasms 0.005720142 2 0 BeFree_LHGDN
Churg-Strauss Syndrome 0.002995792 1 0 BeFree_LHGDN
Eosinophilia 0.002995792 1 0 BeFree_LHGDN
Leukemia, Myelocytic, Acute 0.002995792 1 0 BeFree_LHGDN
Mammary Neoplasms 0.002995792 2 0 BeFree_LHGDN
Pancreatitis, Chronic 0.00272435 1 0 LHGDN
Malignant neoplasm of breast 0.002638474 2 0 BeFree_GAD
Multiple Myeloma 0.002367032 1 0 GAD
Down Syndrome 0.000814326 3 0 BeFree
Glioma 0.000814326 3 0 BeFree
melanoma 0.000814326 3 0 BeFree
Malignant neoplasm of prostate 0.000814326 3 0 BeFree
Malignant tumor of colon 0.000542884 2 0 BeFree
Mental Retardation 0.000542884 2 0 BeFree
Neuroblastoma 0.000542884 2 0 BeFree
Pancreatic carcinoma 0.000542884 2 0 BeFree
Malignant neoplasm of pancreas 0.000542884 2 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Colon Carcinoma 0.000542884 2 0 BeFree
Central neuroblastoma 0.000542884 2 0 BeFree
Liver carcinoma 0.000542884 2 0 BeFree
Adenocarcinoma 0.000271442 1 0 BeFree
Cystadenoma 0.000271442 1 0 BeFree
Hypercholesterolemia, Familial 0.000271442 1 0 BeFree
Acute Promyelocytic Leukemia 0.000271442 1 0 BeFree
Leukopenia 0.000271442 1 0 BeFree
Lupus Erythematosus, Systemic 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Neutropenia 0.000271442 1 0 BeFree
Malignant neoplasm of mouth 0.000271442 1 0 BeFree
Cholangiocarcinoma 0.000271442 1 0 BeFree
Lip and Oral Cavity Carcinoma 0.000271442 1 0 BeFree
Dysmorphic features 0.000271442 1 0 BeFree
Secondary malignant neoplasm of liver 0.000271442 1 0 BeFree
Epithelial ovarian cancer 0.000271442 1 0 BeFree
ovarian neoplasm 0.000271442 1 0 BeFree
Partial Trisomy 0.000271442 1 0 BeFree
Eosinophilic disorder 0.000271442 1 0 BeFree
Disorder characterized by eosinophilia 0.000271442 1 0 BeFree
DOWN SYNDROME CRITICAL REGION 0.000271442 1 0 BeFree
Experimental Organism Basal Cell Carcinoma 0.000271442 1 0 BeFree
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